| Full name: actin related protein T3 | Alias Symbol: ARPM1 | ||
| Type: protein-coding gene | Cytoband: 3q26.2 | ||
| Entrez ID: 84517 | HGNC ID: HGNC:24022 | Ensembl Gene: ENSG00000184378 | OMIM ID: 608534 |
| Drug and gene relationship at DGIdb | |||
Expression of ACTRT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACTRT3 | 84517 | 223665_at | 0.6812 | 0.2928 | |
| GSE26886 | ACTRT3 | 84517 | 223665_at | 0.0027 | 0.9899 | |
| GSE45670 | ACTRT3 | 84517 | 223665_at | 0.6717 | 0.0134 | |
| GSE53622 | ACTRT3 | 84517 | 153926 | 0.2784 | 0.0000 | |
| GSE53624 | ACTRT3 | 84517 | 153926 | 0.5309 | 0.0000 | |
| GSE63941 | ACTRT3 | 84517 | 223665_at | -1.3434 | 0.0634 | |
| GSE77861 | ACTRT3 | 84517 | 223665_at | 0.1186 | 0.3345 | |
| SRP064894 | ACTRT3 | 84517 | RNAseq | 0.6349 | 0.0147 | |
| SRP133303 | ACTRT3 | 84517 | RNAseq | 0.5948 | 0.0747 | |
| SRP159526 | ACTRT3 | 84517 | RNAseq | 0.9268 | 0.0063 | |
| SRP219564 | ACTRT3 | 84517 | RNAseq | 0.6819 | 0.3417 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ACTRT3 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ACTRT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACTRT3 | 84517 | 22 | 0 | 8 | |
| GSE20123 | ACTRT3 | 84517 | 22 | 0 | 8 | |
| GSE43470 | ACTRT3 | 84517 | 24 | 0 | 19 | |
| GSE46452 | ACTRT3 | 84517 | 19 | 1 | 39 | |
| GSE47630 | ACTRT3 | 84517 | 27 | 2 | 11 | |
| GSE54993 | ACTRT3 | 84517 | 1 | 14 | 55 | |
| GSE54994 | ACTRT3 | 84517 | 41 | 0 | 12 | |
| GSE60625 | ACTRT3 | 84517 | 0 | 6 | 5 | |
| GSE74703 | ACTRT3 | 84517 | 20 | 0 | 16 | |
| GSE74704 | ACTRT3 | 84517 | 14 | 0 | 6 | |
| TCGA | ACTRT3 | 84517 | 80 | 0 | 16 |
Total number of gains: 270; Total number of losses: 23; Total Number of normals: 195.
Somatic mutations of ACTRT3:
Generating mutation plots.
Highly correlated genes for ACTRT3:
Showing top 20/68 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACTRT3 | TPR | 0.731544 | 3 | 0 | 3 |
| ACTRT3 | EXOC8 | 0.656015 | 3 | 0 | 3 |
| ACTRT3 | TFDP1 | 0.635937 | 3 | 0 | 3 |
| ACTRT3 | UXS1 | 0.620636 | 3 | 0 | 3 |
| ACTRT3 | FZD6 | 0.618187 | 3 | 0 | 3 |
| ACTRT3 | HSPH1 | 0.6098 | 5 | 0 | 3 |
| ACTRT3 | ATF2 | 0.609184 | 3 | 0 | 3 |
| ACTRT3 | SLC33A1 | 0.606634 | 5 | 0 | 5 |
| ACTRT3 | PRRC2C | 0.605675 | 4 | 0 | 4 |
| ACTRT3 | GRK4 | 0.602733 | 3 | 0 | 3 |
| ACTRT3 | TEX10 | 0.59438 | 3 | 0 | 3 |
| ACTRT3 | CEP19 | 0.587572 | 3 | 0 | 3 |
| ACTRT3 | CYB561A3 | 0.586195 | 3 | 0 | 3 |
| ACTRT3 | TMEM138 | 0.581349 | 5 | 0 | 4 |
| ACTRT3 | MLEC | 0.573117 | 4 | 0 | 3 |
| ACTRT3 | TIMM17A | 0.571278 | 6 | 0 | 5 |
| ACTRT3 | TAF1A | 0.570041 | 4 | 0 | 4 |
| ACTRT3 | PUS1 | 0.569764 | 4 | 0 | 3 |
| ACTRT3 | MTDH | 0.568539 | 5 | 0 | 3 |
| ACTRT3 | RRP15 | 0.565941 | 4 | 0 | 3 |
For details and further investigation, click here
