| Full name: parkin coregulated | Alias Symbol: PARK2CRG|FLJ32724|Glup|HAK005771 | ||
| Type: protein-coding gene | Cytoband: 6q26 | ||
| Entrez ID: 135138 | HGNC ID: HGNC:19152 | Ensembl Gene: ENSG00000112530 | OMIM ID: 608427 |
| Drug and gene relationship at DGIdb | |||
Expression of PACRG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PACRG | 135138 | 215472_at | -0.1407 | 0.5123 | |
| GSE20347 | PACRG | 135138 | 215472_at | -0.0517 | 0.5222 | |
| GSE23400 | PACRG | 135138 | 215472_at | -0.1371 | 0.0000 | |
| GSE26886 | PACRG | 135138 | 215472_at | 0.0158 | 0.9207 | |
| GSE29001 | PACRG | 135138 | 214204_at | -0.2462 | 0.2138 | |
| GSE38129 | PACRG | 135138 | 214204_at | 0.0212 | 0.8833 | |
| GSE45670 | PACRG | 135138 | 215472_at | -0.1288 | 0.2468 | |
| GSE53622 | PACRG | 135138 | 17757 | -0.7239 | 0.0000 | |
| GSE53624 | PACRG | 135138 | 17757 | -1.5008 | 0.0000 | |
| GSE63941 | PACRG | 135138 | 215472_at | 0.2420 | 0.1145 | |
| GSE77861 | PACRG | 135138 | 215472_at | -0.0704 | 0.4530 | |
| GSE97050 | PACRG | 135138 | A_23_P170901 | -0.1582 | 0.5498 | |
| SRP133303 | PACRG | 135138 | RNAseq | 0.2846 | 0.4622 | |
| SRP159526 | PACRG | 135138 | RNAseq | -0.2719 | 0.6555 | |
| SRP193095 | PACRG | 135138 | RNAseq | -0.3879 | 0.0211 | |
| SRP219564 | PACRG | 135138 | RNAseq | -1.0920 | 0.0064 | |
| TCGA | PACRG | 135138 | RNAseq | -1.8029 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by PACRG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PACRG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PACRG | 135138 | 3 | 5 | 22 | |
| GSE20123 | PACRG | 135138 | 3 | 4 | 23 | |
| GSE43470 | PACRG | 135138 | 3 | 1 | 39 | |
| GSE46452 | PACRG | 135138 | 3 | 10 | 46 | |
| GSE47630 | PACRG | 135138 | 8 | 5 | 27 | |
| GSE54993 | PACRG | 135138 | 4 | 4 | 62 | |
| GSE54994 | PACRG | 135138 | 8 | 9 | 36 | |
| GSE60625 | PACRG | 135138 | 1 | 1 | 9 | |
| GSE74703 | PACRG | 135138 | 3 | 1 | 32 | |
| GSE74704 | PACRG | 135138 | 2 | 2 | 16 | |
| TCGA | PACRG | 135138 | 14 | 24 | 58 |
Total number of gains: 52; Total number of losses: 66; Total Number of normals: 370.
Somatic mutations of PACRG:
Generating mutation plots.
Highly correlated genes for PACRG:
Showing top 20/194 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PACRG | ADAL | 0.740556 | 3 | 0 | 3 |
| PACRG | GIPC3 | 0.647743 | 4 | 0 | 3 |
| PACRG | PRSS33 | 0.63052 | 3 | 0 | 3 |
| PACRG | PPM1M | 0.628395 | 3 | 0 | 3 |
| PACRG | ZMAT4 | 0.627088 | 5 | 0 | 4 |
| PACRG | CACNA1G-AS1 | 0.622454 | 3 | 0 | 3 |
| PACRG | SOX10 | 0.621424 | 7 | 0 | 5 |
| PACRG | FAM135B | 0.618445 | 3 | 0 | 3 |
| PACRG | EGFLAM-AS2 | 0.608423 | 4 | 0 | 4 |
| PACRG | EPHA7 | 0.60371 | 3 | 0 | 3 |
| PACRG | LINC01210 | 0.603598 | 4 | 0 | 3 |
| PACRG | FBP2 | 0.602859 | 4 | 0 | 3 |
| PACRG | KLHL41 | 0.602191 | 3 | 0 | 3 |
| PACRG | NPTXR | 0.59718 | 5 | 0 | 3 |
| PACRG | KIAA0408 | 0.595482 | 5 | 0 | 3 |
| PACRG | OR4D2 | 0.592016 | 4 | 0 | 3 |
| PACRG | VIT | 0.591095 | 4 | 0 | 3 |
| PACRG | CSN2 | 0.590286 | 5 | 0 | 4 |
| PACRG | SPATA6 | 0.588793 | 6 | 0 | 5 |
| PACRG | SLC1A7 | 0.58836 | 4 | 0 | 3 |
For details and further investigation, click here
