| Full name: adenosine deaminase RNA specific B2 (inactive) | Alias Symbol: RED2|hRED2|ADAR3 | ||
| Type: protein-coding gene | Cytoband: 10p15.3 | ||
| Entrez ID: 105 | HGNC ID: HGNC:227 | Ensembl Gene: ENSG00000185736 | OMIM ID: 602065 |
| Drug and gene relationship at DGIdb | |||
Expression of ADARB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADARB2 | 105 | 237437_s_at | -0.1374 | 0.6084 | |
| GSE20347 | ADARB2 | 105 | 220648_at | -0.1009 | 0.1635 | |
| GSE23400 | ADARB2 | 105 | 220648_at | -0.0690 | 0.0015 | |
| GSE26886 | ADARB2 | 105 | 237437_s_at | 0.1372 | 0.1683 | |
| GSE29001 | ADARB2 | 105 | 220648_at | -0.0487 | 0.7126 | |
| GSE38129 | ADARB2 | 105 | 220648_at | -0.0749 | 0.2746 | |
| GSE45670 | ADARB2 | 105 | 237437_s_at | 0.0692 | 0.5145 | |
| GSE53622 | ADARB2 | 105 | 44583 | -0.8346 | 0.0004 | |
| GSE53624 | ADARB2 | 105 | 65824 | -0.4729 | 0.0006 | |
| GSE63941 | ADARB2 | 105 | 237437_s_at | 0.2052 | 0.3082 | |
| GSE77861 | ADARB2 | 105 | 237437_s_at | -0.0972 | 0.4736 | |
| SRP064894 | ADARB2 | 105 | RNAseq | -1.3185 | 0.0001 | |
| SRP133303 | ADARB2 | 105 | RNAseq | -1.2198 | 0.0001 | |
| SRP159526 | ADARB2 | 105 | RNAseq | -0.2458 | 0.7380 | |
| SRP193095 | ADARB2 | 105 | RNAseq | -0.0289 | 0.9091 | |
| SRP219564 | ADARB2 | 105 | RNAseq | 0.4328 | 0.6107 | |
| TCGA | ADARB2 | 105 | RNAseq | 0.2256 | 0.6403 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ADARB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADARB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADARB2 | 105 | 4 | 10 | 16 | |
| GSE20123 | ADARB2 | 105 | 5 | 10 | 15 | |
| GSE43470 | ADARB2 | 105 | 3 | 8 | 32 | |
| GSE46452 | ADARB2 | 105 | 2 | 14 | 43 | |
| GSE47630 | ADARB2 | 105 | 5 | 15 | 20 | |
| GSE54993 | ADARB2 | 105 | 11 | 0 | 59 | |
| GSE54994 | ADARB2 | 105 | 4 | 10 | 39 | |
| GSE60625 | ADARB2 | 105 | 0 | 0 | 11 | |
| GSE74703 | ADARB2 | 105 | 2 | 5 | 29 | |
| GSE74704 | ADARB2 | 105 | 1 | 9 | 10 | |
| TCGA | ADARB2 | 105 | 19 | 26 | 51 |
Total number of gains: 56; Total number of losses: 107; Total Number of normals: 325.
Somatic mutations of ADARB2:
Generating mutation plots.
Highly correlated genes for ADARB2:
Showing top 20/514 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADARB2 | IGSF9B | 0.684568 | 3 | 0 | 3 |
| ADARB2 | PNPLA7 | 0.681875 | 3 | 0 | 3 |
| ADARB2 | NOXA1 | 0.674084 | 3 | 0 | 3 |
| ADARB2 | HTR1D | 0.673947 | 3 | 0 | 3 |
| ADARB2 | IFNA4 | 0.669702 | 3 | 0 | 3 |
| ADARB2 | PDE3B | 0.667229 | 3 | 0 | 3 |
| ADARB2 | SLC1A6 | 0.667098 | 3 | 0 | 3 |
| ADARB2 | LZTS1 | 0.666209 | 4 | 0 | 4 |
| ADARB2 | LMAN1L | 0.665194 | 4 | 0 | 4 |
| ADARB2 | IL25 | 0.664573 | 3 | 0 | 3 |
| ADARB2 | SLC5A4 | 0.657105 | 3 | 0 | 3 |
| ADARB2 | CHRD | 0.656719 | 3 | 0 | 3 |
| ADARB2 | AQP8 | 0.652429 | 3 | 0 | 3 |
| ADARB2 | OVOL3 | 0.651099 | 4 | 0 | 4 |
| ADARB2 | IL17A | 0.648915 | 3 | 0 | 3 |
| ADARB2 | ARR3 | 0.648209 | 4 | 0 | 4 |
| ADARB2 | ZNF574 | 0.643392 | 3 | 0 | 3 |
| ADARB2 | OR2S2 | 0.641743 | 5 | 0 | 5 |
| ADARB2 | GABRR2 | 0.641465 | 3 | 0 | 3 |
| ADARB2 | KCNE1 | 0.641446 | 4 | 0 | 3 |
For details and further investigation, click here
