| Full name: aspartylglucosaminidase | Alias Symbol: ASRG | ||
| Type: protein-coding gene | Cytoband: 4q34.3 | ||
| Entrez ID: 175 | HGNC ID: HGNC:318 | Ensembl Gene: ENSG00000038002 | OMIM ID: 613228 |
| Drug and gene relationship at DGIdb | |||
Expression of AGA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGA | 175 | 204332_s_at | -0.4245 | 0.6130 | |
| GSE20347 | AGA | 175 | 204332_s_at | -0.9857 | 0.0000 | |
| GSE23400 | AGA | 175 | 204332_s_at | -0.3326 | 0.0004 | |
| GSE26886 | AGA | 175 | 204332_s_at | -0.6516 | 0.0073 | |
| GSE29001 | AGA | 175 | 204332_s_at | -0.6109 | 0.0403 | |
| GSE38129 | AGA | 175 | 204332_s_at | -0.4417 | 0.0752 | |
| GSE45670 | AGA | 175 | 204332_s_at | -0.3233 | 0.1774 | |
| GSE53622 | AGA | 175 | 134 | -0.5232 | 0.0000 | |
| GSE53624 | AGA | 175 | 134 | -0.9488 | 0.0000 | |
| GSE63941 | AGA | 175 | 204332_s_at | -0.0379 | 0.9731 | |
| GSE77861 | AGA | 175 | 204332_s_at | -0.7668 | 0.1297 | |
| GSE97050 | AGA | 175 | A_23_P7099 | 0.3244 | 0.3624 | |
| SRP007169 | AGA | 175 | RNAseq | -2.3883 | 0.0000 | |
| SRP008496 | AGA | 175 | RNAseq | -1.8909 | 0.0000 | |
| SRP064894 | AGA | 175 | RNAseq | -0.6522 | 0.0006 | |
| SRP133303 | AGA | 175 | RNAseq | -0.0260 | 0.9301 | |
| SRP159526 | AGA | 175 | RNAseq | -0.5099 | 0.1997 | |
| SRP193095 | AGA | 175 | RNAseq | -1.2112 | 0.0000 | |
| SRP219564 | AGA | 175 | RNAseq | -1.0996 | 0.0164 | |
| TCGA | AGA | 175 | RNAseq | 0.1033 | 0.1381 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by AGA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AGA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AGA | 175 | 1 | 10 | 19 | |
| GSE20123 | AGA | 175 | 1 | 10 | 19 | |
| GSE43470 | AGA | 175 | 0 | 14 | 29 | |
| GSE46452 | AGA | 175 | 1 | 36 | 22 | |
| GSE47630 | AGA | 175 | 0 | 22 | 18 | |
| GSE54993 | AGA | 175 | 10 | 0 | 60 | |
| GSE54994 | AGA | 175 | 2 | 12 | 39 | |
| GSE60625 | AGA | 175 | 0 | 0 | 11 | |
| GSE74703 | AGA | 175 | 0 | 12 | 24 | |
| GSE74704 | AGA | 175 | 0 | 5 | 15 | |
| TCGA | AGA | 175 | 10 | 35 | 51 |
Total number of gains: 25; Total number of losses: 156; Total Number of normals: 307.
Somatic mutations of AGA:
Generating mutation plots.
Highly correlated genes for AGA:
Showing top 20/814 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGA | ZNF215 | 0.699143 | 3 | 0 | 3 |
| AGA | CDC42SE1 | 0.689517 | 3 | 0 | 3 |
| AGA | TYSND1 | 0.685497 | 3 | 0 | 3 |
| AGA | STK38 | 0.678393 | 3 | 0 | 3 |
| AGA | MYL12B | 0.678204 | 3 | 0 | 3 |
| AGA | C15orf48 | 0.667604 | 5 | 0 | 5 |
| AGA | ECHDC1 | 0.661383 | 3 | 0 | 3 |
| AGA | OR7E24 | 0.654282 | 3 | 0 | 3 |
| AGA | SLC25A39 | 0.651438 | 3 | 0 | 3 |
| AGA | SLC35B3 | 0.650546 | 3 | 0 | 3 |
| AGA | PGM3 | 0.648953 | 3 | 0 | 3 |
| AGA | TLE4 | 0.646015 | 3 | 0 | 3 |
| AGA | HSD17B4 | 0.645522 | 11 | 0 | 9 |
| AGA | ARPC3 | 0.645091 | 10 | 0 | 8 |
| AGA | IRAK2 | 0.642646 | 6 | 0 | 5 |
| AGA | GIMAP8 | 0.64149 | 4 | 0 | 3 |
| AGA | ARF5 | 0.639426 | 5 | 0 | 5 |
| AGA | RGS17 | 0.638678 | 3 | 0 | 3 |
| AGA | MS4A6A | 0.638029 | 3 | 0 | 3 |
| AGA | TPD52L2 | 0.635816 | 3 | 0 | 3 |
For details and further investigation, click here
