| Full name: ADP ribosylation factor 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q32.1 | ||
| Entrez ID: 381 | HGNC ID: HGNC:658 | Ensembl Gene: ENSG00000004059 | OMIM ID: 103188 |
| Drug and gene relationship at DGIdb | |||
Expression of ARF5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARF5 | 381 | 201526_at | -0.1052 | 0.8880 | |
| GSE20347 | ARF5 | 381 | 201526_at | -0.6829 | 0.0000 | |
| GSE23400 | ARF5 | 381 | 201526_at | -0.1399 | 0.0612 | |
| GSE26886 | ARF5 | 381 | 201526_at | -1.3014 | 0.0000 | |
| GSE29001 | ARF5 | 381 | 201526_at | -0.6206 | 0.0165 | |
| GSE38129 | ARF5 | 381 | 201526_at | -0.2547 | 0.0717 | |
| GSE45670 | ARF5 | 381 | 201526_at | -0.1511 | 0.2219 | |
| GSE53622 | ARF5 | 381 | 12226 | -0.6971 | 0.0000 | |
| GSE53624 | ARF5 | 381 | 12226 | -0.5219 | 0.0000 | |
| GSE63941 | ARF5 | 381 | 201526_at | -0.1976 | 0.5676 | |
| GSE77861 | ARF5 | 381 | 201526_at | -0.1607 | 0.4752 | |
| GSE97050 | ARF5 | 381 | A_33_P3260777 | -0.3290 | 0.2144 | |
| SRP007169 | ARF5 | 381 | RNAseq | -1.4581 | 0.0001 | |
| SRP008496 | ARF5 | 381 | RNAseq | -1.1969 | 0.0000 | |
| SRP064894 | ARF5 | 381 | RNAseq | 0.0561 | 0.8540 | |
| SRP133303 | ARF5 | 381 | RNAseq | -0.3202 | 0.0719 | |
| SRP159526 | ARF5 | 381 | RNAseq | -0.4587 | 0.0197 | |
| SRP193095 | ARF5 | 381 | RNAseq | -0.8288 | 0.0000 | |
| SRP219564 | ARF5 | 381 | RNAseq | -0.6412 | 0.0245 | |
| TCGA | ARF5 | 381 | RNAseq | 0.0994 | 0.0675 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ARF5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARF5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARF5 | 381 | 7 | 1 | 22 | |
| GSE20123 | ARF5 | 381 | 7 | 2 | 21 | |
| GSE43470 | ARF5 | 381 | 2 | 3 | 38 | |
| GSE46452 | ARF5 | 381 | 7 | 2 | 50 | |
| GSE47630 | ARF5 | 381 | 7 | 4 | 29 | |
| GSE54993 | ARF5 | 381 | 3 | 5 | 62 | |
| GSE54994 | ARF5 | 381 | 9 | 7 | 37 | |
| GSE60625 | ARF5 | 381 | 0 | 0 | 11 | |
| GSE74703 | ARF5 | 381 | 2 | 3 | 31 | |
| GSE74704 | ARF5 | 381 | 3 | 2 | 15 | |
| TCGA | ARF5 | 381 | 27 | 22 | 47 |
Total number of gains: 74; Total number of losses: 51; Total Number of normals: 363.
Somatic mutations of ARF5:
Generating mutation plots.
Highly correlated genes for ARF5:
Showing top 20/1230 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARF5 | AKT1S1 | 0.759026 | 4 | 0 | 4 |
| ARF5 | ROR1 | 0.7457 | 3 | 0 | 3 |
| ARF5 | HMGCS1 | 0.741043 | 3 | 0 | 3 |
| ARF5 | PCNT | 0.740372 | 3 | 0 | 3 |
| ARF5 | RNF207 | 0.740246 | 3 | 0 | 3 |
| ARF5 | PRPF38A | 0.719525 | 3 | 0 | 3 |
| ARF5 | KDM4A | 0.719403 | 3 | 0 | 3 |
| ARF5 | TMEM120A | 0.718418 | 6 | 0 | 5 |
| ARF5 | TMEM218 | 0.706692 | 3 | 0 | 3 |
| ARF5 | CCIN | 0.706062 | 3 | 0 | 3 |
| ARF5 | CAPN14 | 0.705996 | 3 | 0 | 3 |
| ARF5 | DDI2 | 0.705797 | 3 | 0 | 3 |
| ARF5 | PRELID1 | 0.702693 | 3 | 0 | 3 |
| ARF5 | BRWD3 | 0.702276 | 3 | 0 | 3 |
| ARF5 | STRN | 0.702138 | 4 | 0 | 4 |
| ARF5 | MPZL3 | 0.702132 | 5 | 0 | 5 |
| ARF5 | EBPL | 0.701061 | 4 | 0 | 3 |
| ARF5 | CCNDBP1 | 0.7006 | 3 | 0 | 3 |
| ARF5 | MRPL27 | 0.695907 | 3 | 0 | 3 |
| ARF5 | NIPAL1 | 0.694428 | 3 | 0 | 3 |
For details and further investigation, click here
