| Full name: regulator of G protein signaling 17 | Alias Symbol: RGSZ2|RGS-17 | ||
| Type: protein-coding gene | Cytoband: 6q25.2 | ||
| Entrez ID: 26575 | HGNC ID: HGNC:14088 | Ensembl Gene: ENSG00000091844 | OMIM ID: 607191 |
Expression of RGS17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RGS17 | 26575 | 220334_at | -0.3658 | 0.5965 | |
| GSE20347 | RGS17 | 26575 | 220334_at | -0.3278 | 0.0685 | |
| GSE23400 | RGS17 | 26575 | 220334_at | -0.1971 | 0.0000 | |
| GSE26886 | RGS17 | 26575 | 220334_at | -2.4000 | 0.0001 | |
| GSE29001 | RGS17 | 26575 | 220334_at | -1.0628 | 0.0034 | |
| GSE38129 | RGS17 | 26575 | 220334_at | -0.2718 | 0.2352 | |
| GSE45670 | RGS17 | 26575 | 220334_at | -0.0304 | 0.9585 | |
| GSE53622 | RGS17 | 26575 | 43358 | -1.0720 | 0.0000 | |
| GSE53624 | RGS17 | 26575 | 43358 | -1.6684 | 0.0000 | |
| GSE63941 | RGS17 | 26575 | 220334_at | -1.3775 | 0.1201 | |
| GSE77861 | RGS17 | 26575 | 220334_at | -0.1115 | 0.7876 | |
| SRP007169 | RGS17 | 26575 | RNAseq | -1.8364 | 0.0003 | |
| SRP064894 | RGS17 | 26575 | RNAseq | -0.8550 | 0.0023 | |
| SRP133303 | RGS17 | 26575 | RNAseq | -0.1934 | 0.4329 | |
| SRP159526 | RGS17 | 26575 | RNAseq | -0.8231 | 0.0157 | |
| SRP193095 | RGS17 | 26575 | RNAseq | -0.7063 | 0.0000 | |
| SRP219564 | RGS17 | 26575 | RNAseq | -0.3974 | 0.5537 | |
| TCGA | RGS17 | 26575 | RNAseq | 0.0260 | 0.9357 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by RGS17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RGS17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RGS17 | 26575 | 1 | 4 | 25 | |
| GSE20123 | RGS17 | 26575 | 1 | 3 | 26 | |
| GSE43470 | RGS17 | 26575 | 4 | 0 | 39 | |
| GSE46452 | RGS17 | 26575 | 3 | 10 | 46 | |
| GSE47630 | RGS17 | 26575 | 9 | 4 | 27 | |
| GSE54993 | RGS17 | 26575 | 3 | 2 | 65 | |
| GSE54994 | RGS17 | 26575 | 8 | 8 | 37 | |
| GSE60625 | RGS17 | 26575 | 0 | 1 | 10 | |
| GSE74703 | RGS17 | 26575 | 4 | 0 | 32 | |
| GSE74704 | RGS17 | 26575 | 0 | 1 | 19 | |
| TCGA | RGS17 | 26575 | 13 | 20 | 63 |
Total number of gains: 46; Total number of losses: 53; Total Number of normals: 389.
Somatic mutations of RGS17:
Generating mutation plots.
Highly correlated genes for RGS17:
Showing top 20/430 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RGS17 | AGA | 0.638678 | 3 | 0 | 3 |
| RGS17 | SLC46A2 | 0.633109 | 5 | 0 | 4 |
| RGS17 | PPP4R1 | 0.631984 | 4 | 0 | 4 |
| RGS17 | LINC01214 | 0.631766 | 5 | 0 | 4 |
| RGS17 | ORMDL2 | 0.625651 | 3 | 0 | 3 |
| RGS17 | GSKIP | 0.623056 | 4 | 0 | 4 |
| RGS17 | SPTLC1 | 0.618118 | 6 | 0 | 5 |
| RGS17 | SH3PXD2A-AS1 | 0.616848 | 3 | 0 | 3 |
| RGS17 | SESN2 | 0.615117 | 5 | 0 | 3 |
| RGS17 | SPINK7 | 0.610998 | 6 | 0 | 6 |
| RGS17 | RAB10 | 0.607872 | 5 | 0 | 5 |
| RGS17 | LYSMD3 | 0.60755 | 4 | 0 | 4 |
| RGS17 | ETHE1 | 0.606977 | 6 | 0 | 5 |
| RGS17 | SPNS2 | 0.605981 | 4 | 0 | 3 |
| RGS17 | UPRT | 0.6051 | 4 | 0 | 3 |
| RGS17 | SRPX2 | 0.603673 | 7 | 0 | 5 |
| RGS17 | GYS2 | 0.60316 | 9 | 0 | 6 |
| RGS17 | SIAE | 0.602315 | 4 | 0 | 4 |
| RGS17 | CNGA1 | 0.600512 | 6 | 0 | 4 |
| RGS17 | HCG22 | 0.599396 | 5 | 0 | 3 |
For details and further investigation, click here
