| Full name: 1-acylglycerol-3-phosphate O-acyltransferase 4 | Alias Symbol: LPAAT-delta|dJ473J16.2 | ||
| Type: protein-coding gene | Cytoband: 6q26 | ||
| Entrez ID: 56895 | HGNC ID: HGNC:20885 | Ensembl Gene: ENSG00000026652 | OMIM ID: 614795 |
| Drug and gene relationship at DGIdb | |||
Expression of AGPAT4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGPAT4 | 56895 | 219693_at | 0.1035 | 0.8964 | |
| GSE20347 | AGPAT4 | 56895 | 219693_at | -0.0990 | 0.6047 | |
| GSE23400 | AGPAT4 | 56895 | 219693_at | 0.0050 | 0.9353 | |
| GSE26886 | AGPAT4 | 56895 | 228667_at | 0.5939 | 0.1199 | |
| GSE29001 | AGPAT4 | 56895 | 219693_at | -0.0697 | 0.7709 | |
| GSE38129 | AGPAT4 | 56895 | 219693_at | 0.0498 | 0.7837 | |
| GSE45670 | AGPAT4 | 56895 | 219693_at | 1.2956 | 0.0000 | |
| GSE53622 | AGPAT4 | 56895 | 71538 | -0.1459 | 0.1969 | |
| GSE53624 | AGPAT4 | 56895 | 71538 | 0.2826 | 0.0010 | |
| GSE63941 | AGPAT4 | 56895 | 219693_at | -1.4087 | 0.0044 | |
| GSE77861 | AGPAT4 | 56895 | 219693_at | 0.2423 | 0.4251 | |
| GSE97050 | AGPAT4 | 56895 | A_32_P141768 | -0.4796 | 0.1242 | |
| SRP007169 | AGPAT4 | 56895 | RNAseq | 0.2214 | 0.6433 | |
| SRP008496 | AGPAT4 | 56895 | RNAseq | -0.0571 | 0.8815 | |
| SRP064894 | AGPAT4 | 56895 | RNAseq | 1.0276 | 0.0000 | |
| SRP133303 | AGPAT4 | 56895 | RNAseq | 0.4406 | 0.0120 | |
| SRP159526 | AGPAT4 | 56895 | RNAseq | -0.1415 | 0.7095 | |
| SRP193095 | AGPAT4 | 56895 | RNAseq | 0.7722 | 0.0005 | |
| SRP219564 | AGPAT4 | 56895 | RNAseq | 0.0447 | 0.9212 | |
| TCGA | AGPAT4 | 56895 | RNAseq | 0.1567 | 0.1610 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by AGPAT4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AGPAT4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AGPAT4 | 56895 | 1 | 5 | 24 | |
| GSE20123 | AGPAT4 | 56895 | 1 | 4 | 25 | |
| GSE43470 | AGPAT4 | 56895 | 3 | 0 | 40 | |
| GSE46452 | AGPAT4 | 56895 | 3 | 10 | 46 | |
| GSE47630 | AGPAT4 | 56895 | 9 | 4 | 27 | |
| GSE54993 | AGPAT4 | 56895 | 4 | 4 | 62 | |
| GSE54994 | AGPAT4 | 56895 | 8 | 9 | 36 | |
| GSE60625 | AGPAT4 | 56895 | 0 | 1 | 10 | |
| GSE74703 | AGPAT4 | 56895 | 3 | 0 | 33 | |
| GSE74704 | AGPAT4 | 56895 | 0 | 2 | 18 | |
| TCGA | AGPAT4 | 56895 | 13 | 22 | 61 |
Total number of gains: 45; Total number of losses: 61; Total Number of normals: 382.
Somatic mutations of AGPAT4:
Generating mutation plots.
Highly correlated genes for AGPAT4:
Showing top 20/201 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGPAT4 | PUM1 | 0.845204 | 3 | 0 | 3 |
| AGPAT4 | GET4 | 0.814685 | 3 | 0 | 3 |
| AGPAT4 | FUBP3 | 0.791187 | 3 | 0 | 3 |
| AGPAT4 | LZIC | 0.750483 | 3 | 0 | 3 |
| AGPAT4 | RAB22A | 0.744779 | 4 | 0 | 4 |
| AGPAT4 | TPD52L2 | 0.739162 | 3 | 0 | 3 |
| AGPAT4 | TTC26 | 0.730706 | 3 | 0 | 3 |
| AGPAT4 | USP14 | 0.728427 | 3 | 0 | 3 |
| AGPAT4 | MLLT1 | 0.71265 | 3 | 0 | 3 |
| AGPAT4 | C9orf85 | 0.710939 | 3 | 0 | 3 |
| AGPAT4 | BDKRB2 | 0.709506 | 3 | 0 | 3 |
| AGPAT4 | KIF3C | 0.707773 | 3 | 0 | 3 |
| AGPAT4 | ANKRD50 | 0.702221 | 3 | 0 | 3 |
| AGPAT4 | CHST2 | 0.695025 | 4 | 0 | 4 |
| AGPAT4 | RRM2B | 0.693163 | 3 | 0 | 3 |
| AGPAT4 | ELOF1 | 0.692974 | 3 | 0 | 3 |
| AGPAT4 | BDNF | 0.692557 | 3 | 0 | 3 |
| AGPAT4 | MAPK6 | 0.686792 | 4 | 0 | 3 |
| AGPAT4 | SLC10A7 | 0.684388 | 3 | 0 | 3 |
| AGPAT4 | SPATA5 | 0.683472 | 3 | 0 | 3 |
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