| Full name: bradykinin receptor B2 | Alias Symbol: BK-2 | ||
| Type: protein-coding gene | Cytoband: 14q32.2 | ||
| Entrez ID: 624 | HGNC ID: HGNC:1030 | Ensembl Gene: ENSG00000168398 | OMIM ID: 113503 |
| Drug and gene relationship at DGIdb | |||
BDKRB2 involved pathways:
Expression of BDKRB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BDKRB2 | 624 | 205870_at | -0.2987 | 0.6391 | |
| GSE20347 | BDKRB2 | 624 | 205870_at | -0.8228 | 0.0009 | |
| GSE23400 | BDKRB2 | 624 | 205870_at | -0.6212 | 0.0000 | |
| GSE26886 | BDKRB2 | 624 | 205870_at | -1.1551 | 0.0124 | |
| GSE29001 | BDKRB2 | 624 | 205870_at | -1.0688 | 0.0052 | |
| GSE38129 | BDKRB2 | 624 | 205870_at | -0.7827 | 0.0007 | |
| GSE45670 | BDKRB2 | 624 | 205870_at | 0.0222 | 0.9253 | |
| GSE53622 | BDKRB2 | 624 | 93849 | -0.8718 | 0.0000 | |
| GSE53624 | BDKRB2 | 624 | 93849 | -0.9778 | 0.0000 | |
| GSE63941 | BDKRB2 | 624 | 205870_at | -4.5740 | 0.0000 | |
| GSE77861 | BDKRB2 | 624 | 205870_at | -0.5842 | 0.1159 | |
| GSE97050 | BDKRB2 | 624 | A_23_P304897 | 0.0620 | 0.8576 | |
| SRP007169 | BDKRB2 | 624 | RNAseq | -0.9731 | 0.1656 | |
| SRP008496 | BDKRB2 | 624 | RNAseq | -0.5511 | 0.4580 | |
| SRP064894 | BDKRB2 | 624 | RNAseq | -0.6565 | 0.0045 | |
| SRP133303 | BDKRB2 | 624 | RNAseq | -0.5696 | 0.0383 | |
| SRP159526 | BDKRB2 | 624 | RNAseq | -1.7639 | 0.0000 | |
| SRP193095 | BDKRB2 | 624 | RNAseq | -0.2765 | 0.2616 | |
| SRP219564 | BDKRB2 | 624 | RNAseq | -0.8406 | 0.1348 | |
| TCGA | BDKRB2 | 624 | RNAseq | -0.0641 | 0.6011 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by BDKRB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BDKRB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BDKRB2 | 624 | 10 | 4 | 16 | |
| GSE20123 | BDKRB2 | 624 | 10 | 3 | 17 | |
| GSE43470 | BDKRB2 | 624 | 8 | 3 | 32 | |
| GSE46452 | BDKRB2 | 624 | 16 | 3 | 40 | |
| GSE47630 | BDKRB2 | 624 | 11 | 8 | 21 | |
| GSE54993 | BDKRB2 | 624 | 3 | 8 | 59 | |
| GSE54994 | BDKRB2 | 624 | 21 | 4 | 28 | |
| GSE60625 | BDKRB2 | 624 | 0 | 2 | 9 | |
| GSE74703 | BDKRB2 | 624 | 6 | 3 | 27 | |
| GSE74704 | BDKRB2 | 624 | 6 | 3 | 11 | |
| TCGA | BDKRB2 | 624 | 30 | 19 | 47 |
Total number of gains: 121; Total number of losses: 60; Total Number of normals: 307.
Somatic mutations of BDKRB2:
Generating mutation plots.
Highly correlated genes for BDKRB2:
Showing top 20/942 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BDKRB2 | BDKRB1 | 0.801428 | 13 | 0 | 13 |
| BDKRB2 | BTBD1 | 0.779595 | 3 | 0 | 3 |
| BDKRB2 | SWAP70 | 0.747325 | 3 | 0 | 3 |
| BDKRB2 | PAPPA | 0.738862 | 3 | 0 | 3 |
| BDKRB2 | GTF3C6 | 0.737332 | 3 | 0 | 3 |
| BDKRB2 | AKIP1 | 0.732435 | 3 | 0 | 3 |
| BDKRB2 | RBX1 | 0.728154 | 3 | 0 | 3 |
| BDKRB2 | AGPAT4 | 0.709506 | 3 | 0 | 3 |
| BDKRB2 | MOB3C | 0.707008 | 3 | 0 | 3 |
| BDKRB2 | ACSL3 | 0.705199 | 4 | 0 | 4 |
| BDKRB2 | TK2 | 0.703146 | 4 | 0 | 3 |
| BDKRB2 | TRIB3 | 0.69802 | 3 | 0 | 3 |
| BDKRB2 | CD109 | 0.695358 | 3 | 0 | 3 |
| BDKRB2 | LACTB | 0.694583 | 4 | 0 | 3 |
| BDKRB2 | PRDX5 | 0.693886 | 5 | 0 | 5 |
| BDKRB2 | ACBD3 | 0.693351 | 4 | 0 | 3 |
| BDKRB2 | PDLIM2 | 0.692249 | 9 | 0 | 8 |
| BDKRB2 | ELOVL1 | 0.690937 | 3 | 0 | 3 |
| BDKRB2 | MAP4 | 0.690147 | 4 | 0 | 3 |
| BDKRB2 | EBPL | 0.689393 | 4 | 0 | 4 |
For details and further investigation, click here
