| Full name: aryl hydrocarbon receptor interacting protein like 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 23746 | HGNC ID: HGNC:359 | Ensembl Gene: ENSG00000129221 | OMIM ID: 604392 |
| Drug and gene relationship at DGIdb | |||
Expression of AIPL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AIPL1 | 23746 | 235731_at | -0.0002 | 0.9994 | |
| GSE20347 | AIPL1 | 23746 | 219977_at | 0.0360 | 0.5491 | |
| GSE23400 | AIPL1 | 23746 | 219977_at | -0.0314 | 0.4437 | |
| GSE26886 | AIPL1 | 23746 | 235731_at | -0.0557 | 0.6482 | |
| GSE29001 | AIPL1 | 23746 | 219977_at | -0.0415 | 0.8737 | |
| GSE38129 | AIPL1 | 23746 | 219977_at | -0.0097 | 0.8756 | |
| GSE45670 | AIPL1 | 23746 | 235731_at | -0.0940 | 0.2470 | |
| GSE53622 | AIPL1 | 23746 | 13395 | 0.4828 | 0.0002 | |
| GSE53624 | AIPL1 | 23746 | 13395 | 0.2807 | 0.0223 | |
| GSE63941 | AIPL1 | 23746 | 235731_at | 0.1410 | 0.4214 | |
| GSE77861 | AIPL1 | 23746 | 235731_at | -0.1412 | 0.3595 | |
| SRP133303 | AIPL1 | 23746 | RNAseq | 0.7379 | 0.0207 | |
| SRP159526 | AIPL1 | 23746 | RNAseq | -0.5522 | 0.3059 | |
| SRP193095 | AIPL1 | 23746 | RNAseq | 0.2685 | 0.1611 | |
| SRP219564 | AIPL1 | 23746 | RNAseq | 0.8476 | 0.3634 | |
| TCGA | AIPL1 | 23746 | RNAseq | 3.3619 | 0.0038 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by AIPL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AIPL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AIPL1 | 23746 | 4 | 2 | 24 | |
| GSE20123 | AIPL1 | 23746 | 4 | 3 | 23 | |
| GSE43470 | AIPL1 | 23746 | 1 | 6 | 36 | |
| GSE46452 | AIPL1 | 23746 | 34 | 1 | 24 | |
| GSE47630 | AIPL1 | 23746 | 7 | 1 | 32 | |
| GSE54993 | AIPL1 | 23746 | 4 | 3 | 63 | |
| GSE54994 | AIPL1 | 23746 | 5 | 8 | 40 | |
| GSE60625 | AIPL1 | 23746 | 4 | 0 | 7 | |
| GSE74703 | AIPL1 | 23746 | 1 | 3 | 32 | |
| GSE74704 | AIPL1 | 23746 | 2 | 1 | 17 | |
| TCGA | AIPL1 | 23746 | 18 | 20 | 58 |
Total number of gains: 84; Total number of losses: 48; Total Number of normals: 356.
Somatic mutations of AIPL1:
Generating mutation plots.
Highly correlated genes for AIPL1:
Showing top 20/357 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AIPL1 | LINC00545 | 0.683218 | 4 | 0 | 4 |
| AIPL1 | CD4 | 0.67478 | 3 | 0 | 3 |
| AIPL1 | PRR34 | 0.674733 | 5 | 0 | 5 |
| AIPL1 | DAB1 | 0.652994 | 4 | 0 | 4 |
| AIPL1 | RFPL3 | 0.647645 | 4 | 0 | 4 |
| AIPL1 | PLCB2 | 0.647413 | 4 | 0 | 4 |
| AIPL1 | KCNJ10 | 0.6424 | 4 | 0 | 4 |
| AIPL1 | CHRD | 0.636892 | 4 | 0 | 3 |
| AIPL1 | SLC34A1 | 0.636393 | 4 | 0 | 3 |
| AIPL1 | ARHGEF38 | 0.635877 | 7 | 0 | 6 |
| AIPL1 | FGB | 0.634955 | 5 | 0 | 3 |
| AIPL1 | EPX | 0.634473 | 5 | 0 | 4 |
| AIPL1 | NHLH1 | 0.633057 | 4 | 0 | 3 |
| AIPL1 | TRAPPC9 | 0.629564 | 4 | 0 | 3 |
| AIPL1 | ZNF446 | 0.629443 | 5 | 0 | 4 |
| AIPL1 | CTAGE1 | 0.625048 | 4 | 0 | 3 |
| AIPL1 | MXD3 | 0.62158 | 4 | 0 | 3 |
| AIPL1 | SLC6A12 | 0.620703 | 4 | 0 | 3 |
| AIPL1 | TMPRSS5 | 0.618988 | 5 | 0 | 3 |
| AIPL1 | ODF1 | 0.618838 | 5 | 0 | 4 |
For details and further investigation, click here
