| Full name: alkB homolog 1, histone H2A dioxygenase | Alias Symbol: hABH|alkB|ABH | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 8846 | HGNC ID: HGNC:17911 | Ensembl Gene: ENSG00000100601 | OMIM ID: 605345 |
Expression of ALKBH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALKBH1 | 8846 | 205621_at | 0.0887 | 0.7346 | |
| GSE20347 | ALKBH1 | 8846 | 205621_at | 0.3263 | 0.0120 | |
| GSE23400 | ALKBH1 | 8846 | 205621_at | 0.4079 | 0.0000 | |
| GSE26886 | ALKBH1 | 8846 | 205621_at | 0.1905 | 0.3133 | |
| GSE29001 | ALKBH1 | 8846 | 205621_at | 0.4054 | 0.0030 | |
| GSE38129 | ALKBH1 | 8846 | 205621_at | 0.2507 | 0.0041 | |
| GSE45670 | ALKBH1 | 8846 | 205621_at | 0.2439 | 0.0824 | |
| GSE53622 | ALKBH1 | 8846 | 64284 | 0.8270 | 0.0000 | |
| GSE53624 | ALKBH1 | 8846 | 64284 | 0.7295 | 0.0000 | |
| GSE63941 | ALKBH1 | 8846 | 205621_at | 0.9121 | 0.0078 | |
| GSE77861 | ALKBH1 | 8846 | 205621_at | 0.3841 | 0.3204 | |
| GSE97050 | ALKBH1 | 8846 | A_23_P14543 | 0.5217 | 0.1584 | |
| SRP007169 | ALKBH1 | 8846 | RNAseq | 0.8594 | 0.0448 | |
| SRP008496 | ALKBH1 | 8846 | RNAseq | 0.6146 | 0.0539 | |
| SRP064894 | ALKBH1 | 8846 | RNAseq | 0.5671 | 0.0002 | |
| SRP133303 | ALKBH1 | 8846 | RNAseq | 0.5669 | 0.0002 | |
| SRP159526 | ALKBH1 | 8846 | RNAseq | 0.5676 | 0.1516 | |
| SRP193095 | ALKBH1 | 8846 | RNAseq | 0.3137 | 0.0041 | |
| SRP219564 | ALKBH1 | 8846 | RNAseq | 0.1699 | 0.5796 | |
| TCGA | ALKBH1 | 8846 | RNAseq | -0.0252 | 0.6748 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ALKBH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALKBH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALKBH1 | 8846 | 8 | 3 | 19 | |
| GSE20123 | ALKBH1 | 8846 | 8 | 3 | 19 | |
| GSE43470 | ALKBH1 | 8846 | 8 | 3 | 32 | |
| GSE46452 | ALKBH1 | 8846 | 16 | 3 | 40 | |
| GSE47630 | ALKBH1 | 8846 | 11 | 8 | 21 | |
| GSE54993 | ALKBH1 | 8846 | 3 | 8 | 59 | |
| GSE54994 | ALKBH1 | 8846 | 19 | 4 | 30 | |
| GSE60625 | ALKBH1 | 8846 | 0 | 2 | 9 | |
| GSE74703 | ALKBH1 | 8846 | 7 | 3 | 26 | |
| GSE74704 | ALKBH1 | 8846 | 3 | 3 | 14 | |
| TCGA | ALKBH1 | 8846 | 31 | 16 | 49 |
Total number of gains: 114; Total number of losses: 56; Total Number of normals: 318.
Somatic mutations of ALKBH1:
Generating mutation plots.
Highly correlated genes for ALKBH1:
Showing top 20/1068 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALKBH1 | SNW1 | 0.737351 | 12 | 0 | 11 |
| ALKBH1 | JKAMP | 0.734979 | 6 | 0 | 6 |
| ALKBH1 | ISCA2 | 0.724098 | 7 | 0 | 7 |
| ALKBH1 | DNASE2 | 0.721513 | 3 | 0 | 3 |
| ALKBH1 | CDK5RAP2 | 0.71357 | 4 | 0 | 4 |
| ALKBH1 | ZFP90 | 0.712186 | 4 | 0 | 3 |
| ALKBH1 | LEMD2 | 0.709141 | 3 | 0 | 3 |
| ALKBH1 | KTI12 | 0.707815 | 3 | 0 | 3 |
| ALKBH1 | CNOT10 | 0.705643 | 3 | 0 | 3 |
| ALKBH1 | ZNF707 | 0.700451 | 3 | 0 | 3 |
| ALKBH1 | GLRX5 | 0.693885 | 12 | 0 | 11 |
| ALKBH1 | LRRC8C | 0.691421 | 3 | 0 | 3 |
| ALKBH1 | COX16 | 0.68879 | 4 | 0 | 4 |
| ALKBH1 | TMX1 | 0.681539 | 9 | 0 | 9 |
| ALKBH1 | LIN52 | 0.681008 | 8 | 0 | 7 |
| ALKBH1 | USP40 | 0.678038 | 3 | 0 | 3 |
| ALKBH1 | SLC35B2 | 0.677321 | 3 | 0 | 3 |
| ALKBH1 | EIF2S1 | 0.676924 | 9 | 0 | 7 |
| ALKBH1 | TDP1 | 0.674972 | 10 | 0 | 8 |
| ALKBH1 | TADA1 | 0.674706 | 3 | 0 | 3 |
For details and further investigation, click here
