| Full name: transmembrane p24 trafficking protein 3 | Alias Symbol: p24B|p24gamma4|p24g4 | ||
| Type: protein-coding gene | Cytoband: 15q25.1 | ||
| Entrez ID: 23423 | HGNC ID: HGNC:28889 | Ensembl Gene: ENSG00000166557 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMED3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMED3 | 23423 | 208837_at | -0.4695 | 0.4825 | |
| GSE20347 | TMED3 | 23423 | 208837_at | -1.2129 | 0.0000 | |
| GSE23400 | TMED3 | 23423 | 208837_at | -0.7334 | 0.0000 | |
| GSE26886 | TMED3 | 23423 | 208837_at | -0.9576 | 0.0000 | |
| GSE29001 | TMED3 | 23423 | 208837_at | -1.0867 | 0.0005 | |
| GSE38129 | TMED3 | 23423 | 208837_at | -0.5482 | 0.0197 | |
| GSE45670 | TMED3 | 23423 | 208837_at | -0.4765 | 0.0118 | |
| GSE53622 | TMED3 | 23423 | 75110 | -0.6882 | 0.0000 | |
| GSE53624 | TMED3 | 23423 | 75110 | -1.0237 | 0.0000 | |
| GSE63941 | TMED3 | 23423 | 208837_at | -1.0383 | 0.0471 | |
| GSE77861 | TMED3 | 23423 | 208837_at | -1.0109 | 0.0011 | |
| GSE97050 | TMED3 | 23423 | A_23_P26173 | 0.2503 | 0.6629 | |
| SRP007169 | TMED3 | 23423 | RNAseq | -1.6815 | 0.0000 | |
| SRP008496 | TMED3 | 23423 | RNAseq | -1.2067 | 0.0002 | |
| SRP064894 | TMED3 | 23423 | RNAseq | -0.9740 | 0.0045 | |
| SRP133303 | TMED3 | 23423 | RNAseq | -0.8798 | 0.0000 | |
| SRP159526 | TMED3 | 23423 | RNAseq | -1.2040 | 0.0000 | |
| SRP193095 | TMED3 | 23423 | RNAseq | -1.2244 | 0.0000 | |
| SRP219564 | TMED3 | 23423 | RNAseq | -0.7952 | 0.1314 | |
| TCGA | TMED3 | 23423 | RNAseq | -0.1002 | 0.0964 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by TMED3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMED3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMED3 | 23423 | 7 | 1 | 22 | |
| GSE20123 | TMED3 | 23423 | 7 | 1 | 22 | |
| GSE43470 | TMED3 | 23423 | 4 | 5 | 34 | |
| GSE46452 | TMED3 | 23423 | 3 | 7 | 49 | |
| GSE47630 | TMED3 | 23423 | 8 | 10 | 22 | |
| GSE54993 | TMED3 | 23423 | 5 | 6 | 59 | |
| GSE54994 | TMED3 | 23423 | 5 | 6 | 42 | |
| GSE60625 | TMED3 | 23423 | 4 | 0 | 7 | |
| GSE74703 | TMED3 | 23423 | 4 | 3 | 29 | |
| GSE74704 | TMED3 | 23423 | 3 | 1 | 16 | |
| TCGA | TMED3 | 23423 | 14 | 15 | 67 |
Total number of gains: 64; Total number of losses: 55; Total Number of normals: 369.
Somatic mutations of TMED3:
Generating mutation plots.
Highly correlated genes for TMED3:
Showing top 20/1077 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMED3 | ULK3 | 0.813438 | 6 | 0 | 6 |
| TMED3 | S100A16 | 0.802821 | 7 | 0 | 7 |
| TMED3 | CCNYL1 | 0.802693 | 4 | 0 | 4 |
| TMED3 | IL18 | 0.78649 | 11 | 0 | 11 |
| TMED3 | CHP1 | 0.7853 | 10 | 0 | 10 |
| TMED3 | MFSD5 | 0.784504 | 11 | 0 | 11 |
| TMED3 | ANKRD22 | 0.784432 | 4 | 0 | 4 |
| TMED3 | SMAGP | 0.782776 | 11 | 0 | 11 |
| TMED3 | TP53I3 | 0.781298 | 12 | 0 | 12 |
| TMED3 | CYSRT1 | 0.779151 | 6 | 0 | 6 |
| TMED3 | PDCD6IP | 0.776507 | 9 | 0 | 9 |
| TMED3 | MCEE | 0.77641 | 6 | 0 | 6 |
| TMED3 | CAPN14 | 0.775658 | 6 | 0 | 6 |
| TMED3 | TSPO | 0.772017 | 10 | 0 | 10 |
| TMED3 | KRT78 | 0.770095 | 6 | 0 | 6 |
| TMED3 | CXCR2 | 0.765548 | 10 | 0 | 10 |
| TMED3 | SFTA2 | 0.764943 | 4 | 0 | 4 |
| TMED3 | RAB11A | 0.764222 | 10 | 0 | 10 |
| TMED3 | NAGK | 0.763921 | 11 | 0 | 10 |
| TMED3 | EHD3 | 0.761911 | 11 | 0 | 11 |
For details and further investigation, click here
