| Full name: receptor accessory protein 1 | Alias Symbol: FLJ13110|SPG31|Yip2a | ||
| Type: protein-coding gene | Cytoband: 2p11.2 | ||
| Entrez ID: 65055 | HGNC ID: HGNC:25786 | Ensembl Gene: ENSG00000068615 | OMIM ID: 609139 |
| Drug and gene relationship at DGIdb | |||
Expression of REEP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | REEP1 | 65055 | 204364_s_at | -1.7961 | 0.3321 | |
| GSE20347 | REEP1 | 65055 | 204364_s_at | -0.3804 | 0.4372 | |
| GSE23400 | REEP1 | 65055 | 204365_s_at | -0.4780 | 0.0001 | |
| GSE26886 | REEP1 | 65055 | 204364_s_at | 0.4568 | 0.4028 | |
| GSE29001 | REEP1 | 65055 | 204365_s_at | -0.0075 | 0.9832 | |
| GSE38129 | REEP1 | 65055 | 204364_s_at | -1.0359 | 0.0104 | |
| GSE45670 | REEP1 | 65055 | 204365_s_at | -1.8093 | 0.0003 | |
| GSE53622 | REEP1 | 65055 | 41127 | -1.8424 | 0.0000 | |
| GSE53624 | REEP1 | 65055 | 41127 | -1.4497 | 0.0000 | |
| GSE63941 | REEP1 | 65055 | 204364_s_at | 2.3349 | 0.1291 | |
| GSE77861 | REEP1 | 65055 | 204365_s_at | 0.3151 | 0.3637 | |
| GSE97050 | REEP1 | 65055 | A_23_P96285 | -1.4706 | 0.1399 | |
| SRP007169 | REEP1 | 65055 | RNAseq | 3.4359 | 0.0002 | |
| SRP064894 | REEP1 | 65055 | RNAseq | -0.9534 | 0.0356 | |
| SRP133303 | REEP1 | 65055 | RNAseq | -1.7558 | 0.0000 | |
| SRP159526 | REEP1 | 65055 | RNAseq | -1.1668 | 0.0199 | |
| SRP193095 | REEP1 | 65055 | RNAseq | 0.5373 | 0.0629 | |
| SRP219564 | REEP1 | 65055 | RNAseq | -1.3210 | 0.2444 | |
| TCGA | REEP1 | 65055 | RNAseq | -1.0063 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 7.
Survival by REEP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of REEP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | REEP1 | 65055 | 9 | 2 | 19 | |
| GSE20123 | REEP1 | 65055 | 9 | 2 | 19 | |
| GSE43470 | REEP1 | 65055 | 4 | 2 | 37 | |
| GSE46452 | REEP1 | 65055 | 2 | 3 | 54 | |
| GSE47630 | REEP1 | 65055 | 7 | 0 | 33 | |
| GSE54993 | REEP1 | 65055 | 0 | 6 | 64 | |
| GSE54994 | REEP1 | 65055 | 10 | 0 | 43 | |
| GSE60625 | REEP1 | 65055 | 0 | 3 | 8 | |
| GSE74703 | REEP1 | 65055 | 4 | 1 | 31 | |
| GSE74704 | REEP1 | 65055 | 7 | 0 | 13 | |
| TCGA | REEP1 | 65055 | 35 | 4 | 57 |
Total number of gains: 87; Total number of losses: 23; Total Number of normals: 378.
Somatic mutations of REEP1:
Generating mutation plots.
Highly correlated genes for REEP1:
Showing top 20/599 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| REEP1 | CYP21A2 | 0.755321 | 3 | 0 | 3 |
| REEP1 | ASB5 | 0.742172 | 6 | 0 | 6 |
| REEP1 | ANKS1B | 0.731606 | 3 | 0 | 3 |
| REEP1 | NACC2 | 0.730419 | 7 | 0 | 7 |
| REEP1 | CLEC3B | 0.729973 | 3 | 0 | 3 |
| REEP1 | PGR | 0.729964 | 5 | 0 | 5 |
| REEP1 | XKR4 | 0.72837 | 5 | 0 | 5 |
| REEP1 | SLITRK3 | 0.728296 | 7 | 0 | 7 |
| REEP1 | SMOC2 | 0.726019 | 7 | 0 | 7 |
| REEP1 | PGM5 | 0.717988 | 8 | 0 | 7 |
| REEP1 | RNF150 | 0.71703 | 5 | 0 | 5 |
| REEP1 | CASQ2 | 0.715624 | 10 | 0 | 9 |
| REEP1 | WEE1 | 0.709423 | 3 | 0 | 3 |
| REEP1 | ATP1A2 | 0.70933 | 9 | 0 | 8 |
| REEP1 | PYGM | 0.70762 | 9 | 0 | 8 |
| REEP1 | ANO5 | 0.70748 | 6 | 0 | 5 |
| REEP1 | PTCHD1 | 0.70729 | 6 | 0 | 5 |
| REEP1 | PI16 | 0.705043 | 4 | 0 | 4 |
| REEP1 | TACR2 | 0.699335 | 9 | 0 | 8 |
| REEP1 | INPP5A | 0.699328 | 8 | 0 | 7 |
For details and further investigation, click here
