| Full name: annexin A2 | Alias Symbol: LIP2 | ||
| Type: protein-coding gene | Cytoband: 15q22.2 | ||
| Entrez ID: 302 | HGNC ID: HGNC:537 | Ensembl Gene: ENSG00000182718 | OMIM ID: 151740 |
| Drug and gene relationship at DGIdb | |||
Expression of ANXA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANXA2 | 302 | 201590_x_at | -0.2964 | 0.5925 | |
| GSE20347 | ANXA2 | 302 | 201590_x_at | -0.6496 | 0.0000 | |
| GSE23400 | ANXA2 | 302 | 210427_x_at | -0.4337 | 0.0000 | |
| GSE26886 | ANXA2 | 302 | 213503_x_at | -0.3072 | 0.0254 | |
| GSE29001 | ANXA2 | 302 | 213503_x_at | -0.7800 | 0.0141 | |
| GSE38129 | ANXA2 | 302 | 210427_x_at | -0.1761 | 0.3896 | |
| GSE45670 | ANXA2 | 302 | 210427_x_at | -0.1437 | 0.1531 | |
| GSE53622 | ANXA2 | 302 | 85558 | -0.3421 | 0.0201 | |
| GSE53624 | ANXA2 | 302 | 85558 | -0.5688 | 0.0000 | |
| GSE63941 | ANXA2 | 302 | 201590_x_at | -0.0470 | 0.8889 | |
| GSE77861 | ANXA2 | 302 | 210427_x_at | -0.2038 | 0.0262 | |
| GSE97050 | ANXA2 | 302 | A_23_P146644 | 0.6448 | 0.3865 | |
| SRP007169 | ANXA2 | 302 | RNAseq | -2.1753 | 0.0000 | |
| SRP008496 | ANXA2 | 302 | RNAseq | -2.1658 | 0.0000 | |
| SRP064894 | ANXA2 | 302 | RNAseq | -0.9124 | 0.0000 | |
| SRP133303 | ANXA2 | 302 | RNAseq | -0.3876 | 0.1494 | |
| SRP159526 | ANXA2 | 302 | RNAseq | -1.2118 | 0.0103 | |
| SRP193095 | ANXA2 | 302 | RNAseq | -0.8232 | 0.0002 | |
| SRP219564 | ANXA2 | 302 | RNAseq | -0.9004 | 0.1423 | |
| TCGA | ANXA2 | 302 | RNAseq | 0.2876 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ANXA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANXA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANXA2 | 302 | 6 | 4 | 20 | |
| GSE20123 | ANXA2 | 302 | 6 | 3 | 21 | |
| GSE43470 | ANXA2 | 302 | 4 | 6 | 33 | |
| GSE46452 | ANXA2 | 302 | 3 | 7 | 49 | |
| GSE47630 | ANXA2 | 302 | 8 | 10 | 22 | |
| GSE54993 | ANXA2 | 302 | 5 | 6 | 59 | |
| GSE54994 | ANXA2 | 302 | 6 | 8 | 39 | |
| GSE60625 | ANXA2 | 302 | 4 | 0 | 7 | |
| GSE74703 | ANXA2 | 302 | 4 | 3 | 29 | |
| GSE74704 | ANXA2 | 302 | 2 | 3 | 15 | |
| TCGA | ANXA2 | 302 | 10 | 16 | 70 |
Total number of gains: 58; Total number of losses: 66; Total Number of normals: 364.
Somatic mutations of ANXA2:
Generating mutation plots.
Highly correlated genes for ANXA2:
Showing top 20/751 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANXA2 | S100A10 | 0.765779 | 13 | 0 | 12 |
| ANXA2 | KRT6C | 0.731981 | 4 | 0 | 3 |
| ANXA2 | GNA15 | 0.72636 | 12 | 0 | 11 |
| ANXA2 | DSG3 | 0.725053 | 10 | 0 | 10 |
| ANXA2 | BTBD11 | 0.713016 | 7 | 0 | 7 |
| ANXA2 | S100A2 | 0.7042 | 9 | 0 | 9 |
| ANXA2 | TMED3 | 0.701275 | 11 | 0 | 8 |
| ANXA2 | PTK6 | 0.70014 | 11 | 0 | 11 |
| ANXA2 | LPAR5 | 0.699721 | 5 | 0 | 5 |
| ANXA2 | SERPINB5 | 0.697382 | 10 | 0 | 10 |
| ANXA2 | FAM83C | 0.689676 | 4 | 0 | 3 |
| ANXA2 | ORMDL2 | 0.688092 | 8 | 0 | 7 |
| ANXA2 | S100A11 | 0.68795 | 11 | 0 | 9 |
| ANXA2 | TMEM154 | 0.687019 | 8 | 0 | 7 |
| ANXA2 | KRT6A | 0.686189 | 10 | 0 | 10 |
| ANXA2 | S100A16 | 0.680541 | 8 | 0 | 7 |
| ANXA2 | SLC37A2 | 0.679644 | 4 | 0 | 4 |
| ANXA2 | C6orf132 | 0.675701 | 7 | 0 | 7 |
| ANXA2 | ANXA1 | 0.675062 | 12 | 0 | 10 |
| ANXA2 | PKP3 | 0.67413 | 12 | 0 | 10 |
For details and further investigation, click here
