| Full name: family with sequence similarity 83 member C | Alias Symbol: dJ614O4.7 | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 128876 | HGNC ID: HGNC:16121 | Ensembl Gene: ENSG00000125998 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM83C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM83C | 128876 | 1556793_a_at | 0.5323 | 0.7201 | |
| GSE26886 | FAM83C | 128876 | 1556793_a_at | -3.0274 | 0.0003 | |
| GSE45670 | FAM83C | 128876 | 1556793_a_at | 0.1173 | 0.8040 | |
| GSE53622 | FAM83C | 128876 | 94983 | -0.4664 | 0.2417 | |
| GSE53624 | FAM83C | 128876 | 94983 | -1.0246 | 0.0000 | |
| GSE63941 | FAM83C | 128876 | 1563805_a_at | 0.0196 | 0.9330 | |
| GSE77861 | FAM83C | 128876 | 1556793_a_at | -0.5254 | 0.4814 | |
| GSE97050 | FAM83C | 128876 | A_23_P409888 | 1.7048 | 0.2882 | |
| SRP007169 | FAM83C | 128876 | RNAseq | -1.4325 | 0.0069 | |
| SRP008496 | FAM83C | 128876 | RNAseq | -1.2731 | 0.1120 | |
| SRP064894 | FAM83C | 128876 | RNAseq | -0.2272 | 0.7087 | |
| SRP133303 | FAM83C | 128876 | RNAseq | -0.9926 | 0.0138 | |
| SRP159526 | FAM83C | 128876 | RNAseq | -1.5913 | 0.0879 | |
| SRP219564 | FAM83C | 128876 | RNAseq | -3.0770 | 0.0062 | |
| TCGA | FAM83C | 128876 | RNAseq | 1.4585 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by FAM83C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM83C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM83C | 128876 | 16 | 0 | 14 | |
| GSE20123 | FAM83C | 128876 | 16 | 0 | 14 | |
| GSE43470 | FAM83C | 128876 | 13 | 0 | 30 | |
| GSE46452 | FAM83C | 128876 | 29 | 0 | 30 | |
| GSE47630 | FAM83C | 128876 | 25 | 0 | 15 | |
| GSE54993 | FAM83C | 128876 | 0 | 17 | 53 | |
| GSE54994 | FAM83C | 128876 | 24 | 0 | 29 | |
| GSE60625 | FAM83C | 128876 | 0 | 0 | 11 | |
| GSE74703 | FAM83C | 128876 | 11 | 0 | 25 | |
| GSE74704 | FAM83C | 128876 | 11 | 0 | 9 | |
| TCGA | FAM83C | 128876 | 49 | 3 | 44 |
Total number of gains: 194; Total number of losses: 20; Total Number of normals: 274.
Somatic mutations of FAM83C:
Generating mutation plots.
Highly correlated genes for FAM83C:
Showing top 20/389 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM83C | KRT75 | 0.764381 | 3 | 0 | 3 |
| FAM83C | PRRG4 | 0.737523 | 5 | 0 | 4 |
| FAM83C | DSC2 | 0.735899 | 6 | 0 | 5 |
| FAM83C | BTBD11 | 0.72871 | 5 | 0 | 5 |
| FAM83C | SERPINB5 | 0.724306 | 6 | 0 | 5 |
| FAM83C | GJB5 | 0.712809 | 5 | 0 | 4 |
| FAM83C | SNORD89 | 0.70988 | 3 | 0 | 3 |
| FAM83C | KRT6A | 0.706206 | 6 | 0 | 4 |
| FAM83C | SPRR1B | 0.706004 | 7 | 0 | 6 |
| FAM83C | SH3RF2 | 0.704959 | 5 | 0 | 5 |
| FAM83C | VDR | 0.703186 | 5 | 0 | 5 |
| FAM83C | FGFR3 | 0.702519 | 5 | 0 | 5 |
| FAM83C | KRT6C | 0.701621 | 4 | 0 | 3 |
| FAM83C | KRT83 | 0.696785 | 3 | 0 | 3 |
| FAM83C | DMKN | 0.695546 | 5 | 0 | 5 |
| FAM83C | SDC1 | 0.695296 | 5 | 0 | 4 |
| FAM83C | DSG3 | 0.691796 | 7 | 0 | 5 |
| FAM83C | ANXA2 | 0.689676 | 4 | 0 | 3 |
| FAM83C | IL20RB | 0.688192 | 5 | 0 | 5 |
| FAM83C | EVPL | 0.685813 | 5 | 0 | 5 |
For details and further investigation, click here
