| Full name: tripartite motif containing 37 | Alias Symbol: KIAA0898|POB1|TEF3 | ||
| Type: protein-coding gene | Cytoband: 17q22 | ||
| Entrez ID: 4591 | HGNC ID: HGNC:7523 | Ensembl Gene: ENSG00000108395 | OMIM ID: 605073 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TRIM37:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIM37 | 4591 | 213009_s_at | 0.4162 | 0.2275 | |
| GSE20347 | TRIM37 | 4591 | 213009_s_at | 0.6594 | 0.0001 | |
| GSE23400 | TRIM37 | 4591 | 213009_s_at | 0.6267 | 0.0000 | |
| GSE26886 | TRIM37 | 4591 | 213009_s_at | 0.0363 | 0.8354 | |
| GSE29001 | TRIM37 | 4591 | 213009_s_at | 0.7152 | 0.0031 | |
| GSE38129 | TRIM37 | 4591 | 213009_s_at | 0.6183 | 0.0000 | |
| GSE45670 | TRIM37 | 4591 | 213009_s_at | 0.0893 | 0.6300 | |
| GSE53622 | TRIM37 | 4591 | 26768 | 0.4359 | 0.0000 | |
| GSE53624 | TRIM37 | 4591 | 26768 | 0.4697 | 0.0000 | |
| GSE63941 | TRIM37 | 4591 | 213009_s_at | 0.0680 | 0.8784 | |
| GSE77861 | TRIM37 | 4591 | 213009_s_at | 0.5001 | 0.0403 | |
| GSE97050 | TRIM37 | 4591 | A_23_P21230 | 0.4185 | 0.2992 | |
| SRP007169 | TRIM37 | 4591 | RNAseq | 0.9170 | 0.0204 | |
| SRP008496 | TRIM37 | 4591 | RNAseq | 0.9588 | 0.0000 | |
| SRP064894 | TRIM37 | 4591 | RNAseq | 0.4813 | 0.0030 | |
| SRP133303 | TRIM37 | 4591 | RNAseq | 0.6510 | 0.0000 | |
| SRP159526 | TRIM37 | 4591 | RNAseq | 0.5036 | 0.0237 | |
| SRP193095 | TRIM37 | 4591 | RNAseq | 0.3797 | 0.0000 | |
| SRP219564 | TRIM37 | 4591 | RNAseq | 0.0668 | 0.8189 | |
| TCGA | TRIM37 | 4591 | RNAseq | 0.1316 | 0.0124 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRIM37 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIM37:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIM37 | 4591 | 6 | 1 | 23 | |
| GSE20123 | TRIM37 | 4591 | 6 | 1 | 23 | |
| GSE43470 | TRIM37 | 4591 | 3 | 0 | 40 | |
| GSE46452 | TRIM37 | 4591 | 32 | 0 | 27 | |
| GSE47630 | TRIM37 | 4591 | 7 | 1 | 32 | |
| GSE54993 | TRIM37 | 4591 | 2 | 5 | 63 | |
| GSE54994 | TRIM37 | 4591 | 8 | 6 | 39 | |
| GSE60625 | TRIM37 | 4591 | 4 | 0 | 7 | |
| GSE74703 | TRIM37 | 4591 | 3 | 0 | 33 | |
| GSE74704 | TRIM37 | 4591 | 5 | 1 | 14 | |
| TCGA | TRIM37 | 4591 | 26 | 7 | 63 |
Total number of gains: 102; Total number of losses: 22; Total Number of normals: 364.
Somatic mutations of TRIM37:
Generating mutation plots.
Highly correlated genes for TRIM37:
Showing top 20/1524 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIM37 | NF1 | 0.75438 | 3 | 0 | 3 |
| TRIM37 | MAD2L2 | 0.730644 | 4 | 0 | 3 |
| TRIM37 | LRP6 | 0.730054 | 4 | 0 | 4 |
| TRIM37 | ASB7 | 0.727494 | 3 | 0 | 3 |
| TRIM37 | GNG10 | 0.714907 | 3 | 0 | 3 |
| TRIM37 | CEP41 | 0.713269 | 4 | 0 | 4 |
| TRIM37 | BRCA1 | 0.698547 | 9 | 0 | 9 |
| TRIM37 | SYS1 | 0.696151 | 3 | 0 | 3 |
| TRIM37 | PPT1 | 0.694631 | 9 | 0 | 8 |
| TRIM37 | TTI2 | 0.692349 | 4 | 0 | 3 |
| TRIM37 | AQP9 | 0.691917 | 3 | 0 | 3 |
| TRIM37 | RHEB | 0.689341 | 10 | 0 | 10 |
| TRIM37 | ARL13B | 0.685257 | 5 | 0 | 4 |
| TRIM37 | CBX1 | 0.683684 | 10 | 0 | 9 |
| TRIM37 | HTRA2 | 0.682597 | 10 | 0 | 8 |
| TRIM37 | ADSL | 0.681202 | 10 | 0 | 10 |
| TRIM37 | PHB | 0.681169 | 9 | 0 | 8 |
| TRIM37 | CDK2AP2 | 0.678524 | 3 | 0 | 3 |
| TRIM37 | LMBR1 | 0.678339 | 5 | 0 | 5 |
| TRIM37 | MSH6 | 0.677877 | 11 | 0 | 9 |
For details and further investigation, click here
