GLB1L

 

Full name: galactosidase beta 1 like Alias Symbol: MGC10771
Type: protein-coding gene Cytoband: 2q35
Entrez ID: 79411 HGNC ID: HGNC:28129 Ensembl Gene: ENSG00000163521 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of GLB1L:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GLB1L 79411 206540_at 0.1454 0.6541
GSE20347 GLB1L 79411 206540_at 0.1734 0.0765
GSE23400 GLB1L 79411 206540_at 0.0147 0.6146
GSE26886 GLB1L 79411 206540_at 0.4049 0.0190
GSE29001 GLB1L 79411 206540_at 0.1155 0.5578
GSE38129 GLB1L 79411 206540_at -0.0443 0.7056
GSE45670 GLB1L 79411 206540_at -0.0201 0.9324
GSE53622 GLB1L 79411 119029 0.4099 0.0060
GSE53624 GLB1L 79411 119029 0.4782 0.0004
GSE63941 GLB1L 79411 206540_at -1.8822 0.0000
GSE77861 GLB1L 79411 206540_at -0.0082 0.9575
GSE97050 GLB1L 79411 A_23_P218579 0.0880 0.6716
SRP007169 GLB1L 79411 RNAseq 2.4832 0.0014
SRP008496 GLB1L 79411 RNAseq 2.5240 0.0000
SRP064894 GLB1L 79411 RNAseq 0.8501 0.0005
SRP133303 GLB1L 79411 RNAseq 0.4977 0.0134
SRP159526 GLB1L 79411 RNAseq 1.2462 0.0044
SRP193095 GLB1L 79411 RNAseq 0.3878 0.0175
SRP219564 GLB1L 79411 RNAseq 0.3798 0.3742
TCGA GLB1L 79411 RNAseq -0.0848 0.5360

Upregulated datasets: 3; Downregulated datasets: 1.  


 

Survival by GLB1L expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GLB1L:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GLB1L 79411 2 14 14
GSE20123 GLB1L 79411 2 13 15
GSE43470 GLB1L 79411 1 7 35
GSE46452 GLB1L 79411 0 5 54
GSE47630 GLB1L 79411 4 5 31
GSE54993 GLB1L 79411 1 2 67
GSE54994 GLB1L 79411 8 9 36
GSE60625 GLB1L 79411 0 3 8
GSE74703 GLB1L 79411 1 5 30
GSE74704 GLB1L 79411 2 7 11
TCGA GLB1L 79411 12 26 58

Total number of gains: 33; Total number of losses: 96; Total Number of normals: 359.  


 

Somatic mutations of GLB1L:

 

Generating mutation plots.

 

Highly correlated genes for GLB1L:

 

Showing top 20/352 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GLB1LFARS20.758251303
GLB1LRILP0.722822303
GLB1LARHGAP170.720219303
GLB1LRRAGB0.71321303
GLB1LPOLR2G0.709676303
GLB1LPDGFRB0.706356404
GLB1LCD163L10.70397303
GLB1LCYP27C10.703113303
GLB1LSLC43A20.702303404
GLB1LPLBD20.693176303
GLB1LTLR10.691629303
GLB1LICAM10.686401303
GLB1LTNFAIP30.684689303
GLB1LLACTB0.682611303
GLB1LPLIN20.679554403
GLB1LIFI27L20.677266303
GLB1LCYP4V20.674325303
GLB1LPSMC3IP0.673753303
GLB1LSEMA6A0.673492504
GLB1LCD1630.67187404

For details and further investigation, click here