| Full name: TARBP2 subunit of RISC loading complex | Alias Symbol: Trbp | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 6895 | HGNC ID: HGNC:11569 | Ensembl Gene: ENSG00000139546 | OMIM ID: 605053 |
| Drug and gene relationship at DGIdb | |||
Expression of TARBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TARBP2 | 6895 | 203677_s_at | 0.4988 | 0.2249 | |
| GSE20347 | TARBP2 | 6895 | 203677_s_at | 0.2586 | 0.0037 | |
| GSE23400 | TARBP2 | 6895 | 203677_s_at | 0.1842 | 0.0000 | |
| GSE26886 | TARBP2 | 6895 | 203677_s_at | 0.0343 | 0.8472 | |
| GSE29001 | TARBP2 | 6895 | 203677_s_at | 0.2882 | 0.1033 | |
| GSE38129 | TARBP2 | 6895 | 203677_s_at | 0.4178 | 0.0000 | |
| GSE45670 | TARBP2 | 6895 | 203677_s_at | 0.5149 | 0.0000 | |
| GSE53622 | TARBP2 | 6895 | 86428 | 0.5174 | 0.0000 | |
| GSE53624 | TARBP2 | 6895 | 86428 | 0.6079 | 0.0000 | |
| GSE63941 | TARBP2 | 6895 | 203677_s_at | 0.3974 | 0.1252 | |
| GSE77861 | TARBP2 | 6895 | 203677_s_at | 0.1681 | 0.1750 | |
| GSE97050 | TARBP2 | 6895 | A_23_P87603 | 0.5026 | 0.1931 | |
| SRP007169 | TARBP2 | 6895 | RNAseq | -0.1048 | 0.7903 | |
| SRP008496 | TARBP2 | 6895 | RNAseq | 0.0852 | 0.7231 | |
| SRP064894 | TARBP2 | 6895 | RNAseq | 0.7267 | 0.0017 | |
| SRP133303 | TARBP2 | 6895 | RNAseq | 0.4706 | 0.0236 | |
| SRP159526 | TARBP2 | 6895 | RNAseq | 0.3312 | 0.1408 | |
| SRP193095 | TARBP2 | 6895 | RNAseq | 0.3032 | 0.0006 | |
| SRP219564 | TARBP2 | 6895 | RNAseq | 0.7627 | 0.0316 | |
| TCGA | TARBP2 | 6895 | RNAseq | 0.1693 | 0.0083 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TARBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TARBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TARBP2 | 6895 | 7 | 1 | 22 | |
| GSE20123 | TARBP2 | 6895 | 7 | 1 | 22 | |
| GSE43470 | TARBP2 | 6895 | 3 | 0 | 40 | |
| GSE46452 | TARBP2 | 6895 | 7 | 1 | 51 | |
| GSE47630 | TARBP2 | 6895 | 10 | 2 | 28 | |
| GSE54993 | TARBP2 | 6895 | 0 | 5 | 65 | |
| GSE54994 | TARBP2 | 6895 | 4 | 1 | 48 | |
| GSE60625 | TARBP2 | 6895 | 0 | 0 | 11 | |
| GSE74703 | TARBP2 | 6895 | 3 | 0 | 33 | |
| GSE74704 | TARBP2 | 6895 | 5 | 1 | 14 | |
| TCGA | TARBP2 | 6895 | 14 | 11 | 71 |
Total number of gains: 60; Total number of losses: 23; Total Number of normals: 405.
Somatic mutations of TARBP2:
Generating mutation plots.
Highly correlated genes for TARBP2:
Showing top 20/767 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TARBP2 | C19orf48 | 0.773173 | 3 | 0 | 3 |
| TARBP2 | BOP1 | 0.760116 | 3 | 0 | 3 |
| TARBP2 | ARHGAP23 | 0.743825 | 3 | 0 | 3 |
| TARBP2 | ZDHHC16 | 0.710409 | 4 | 0 | 4 |
| TARBP2 | MRPL4 | 0.702069 | 5 | 0 | 5 |
| TARBP2 | ANKRD52 | 0.690828 | 4 | 0 | 4 |
| TARBP2 | GRK6 | 0.687448 | 4 | 0 | 3 |
| TARBP2 | E2F7 | 0.680644 | 5 | 0 | 5 |
| TARBP2 | HAUS8 | 0.680408 | 6 | 0 | 5 |
| TARBP2 | BEND3 | 0.673273 | 6 | 0 | 6 |
| TARBP2 | MCM2 | 0.668824 | 11 | 0 | 10 |
| TARBP2 | PAFAH1B3 | 0.666488 | 9 | 0 | 8 |
| TARBP2 | C4orf46 | 0.6663 | 4 | 0 | 4 |
| TARBP2 | ZNF678 | 0.664061 | 3 | 0 | 3 |
| TARBP2 | CDCA8 | 0.661946 | 11 | 0 | 8 |
| TARBP2 | EFTUD2 | 0.661306 | 5 | 0 | 5 |
| TARBP2 | ALDH16A1 | 0.658543 | 6 | 0 | 6 |
| TARBP2 | LRRC45 | 0.653865 | 5 | 0 | 5 |
| TARBP2 | EDARADD | 0.653479 | 5 | 0 | 4 |
| TARBP2 | ASF1B | 0.653276 | 10 | 0 | 8 |
For details and further investigation, click here
