| Full name: AT-rich interaction domain 4A | Alias Symbol: RBP1|RBP-1 | ||
| Type: protein-coding gene | Cytoband: 14q23.1 | ||
| Entrez ID: 5926 | HGNC ID: HGNC:9885 | Ensembl Gene: ENSG00000032219 | OMIM ID: 180201 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ARID4A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARID4A | 5926 | 205062_x_at | -0.1764 | 0.5086 | |
| GSE20347 | ARID4A | 5926 | 205062_x_at | -0.1699 | 0.1690 | |
| GSE23400 | ARID4A | 5926 | 205062_x_at | -0.1007 | 0.0427 | |
| GSE26886 | ARID4A | 5926 | 205062_x_at | -0.6465 | 0.0007 | |
| GSE29001 | ARID4A | 5926 | 205062_x_at | -0.2768 | 0.2165 | |
| GSE38129 | ARID4A | 5926 | 205062_x_at | -0.3151 | 0.0027 | |
| GSE45670 | ARID4A | 5926 | 205062_x_at | -0.4233 | 0.0000 | |
| GSE53622 | ARID4A | 5926 | 73310 | -1.3858 | 0.0000 | |
| GSE53624 | ARID4A | 5926 | 73310 | -2.0117 | 0.0000 | |
| GSE63941 | ARID4A | 5926 | 205062_x_at | -0.4951 | 0.2003 | |
| GSE77861 | ARID4A | 5926 | 205062_x_at | -0.1185 | 0.6795 | |
| GSE97050 | ARID4A | 5926 | A_23_P117515 | -0.4921 | 0.1505 | |
| SRP007169 | ARID4A | 5926 | RNAseq | -0.4499 | 0.2812 | |
| SRP008496 | ARID4A | 5926 | RNAseq | -0.3630 | 0.1722 | |
| SRP064894 | ARID4A | 5926 | RNAseq | -0.5644 | 0.0214 | |
| SRP133303 | ARID4A | 5926 | RNAseq | -0.3564 | 0.0569 | |
| SRP159526 | ARID4A | 5926 | RNAseq | -0.7369 | 0.0000 | |
| SRP193095 | ARID4A | 5926 | RNAseq | -0.4207 | 0.0026 | |
| SRP219564 | ARID4A | 5926 | RNAseq | -0.3924 | 0.3109 | |
| TCGA | ARID4A | 5926 | RNAseq | -0.2653 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ARID4A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARID4A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARID4A | 5926 | 8 | 3 | 19 | |
| GSE20123 | ARID4A | 5926 | 7 | 3 | 20 | |
| GSE43470 | ARID4A | 5926 | 8 | 2 | 33 | |
| GSE46452 | ARID4A | 5926 | 16 | 3 | 40 | |
| GSE47630 | ARID4A | 5926 | 11 | 10 | 19 | |
| GSE54993 | ARID4A | 5926 | 3 | 8 | 59 | |
| GSE54994 | ARID4A | 5926 | 19 | 4 | 30 | |
| GSE60625 | ARID4A | 5926 | 0 | 2 | 9 | |
| GSE74703 | ARID4A | 5926 | 7 | 2 | 27 | |
| GSE74704 | ARID4A | 5926 | 3 | 2 | 15 | |
| TCGA | ARID4A | 5926 | 32 | 14 | 50 |
Total number of gains: 114; Total number of losses: 53; Total Number of normals: 321.
Somatic mutations of ARID4A:
Generating mutation plots.
Highly correlated genes for ARID4A:
Showing top 20/607 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARID4A | KMT2D | 0.67908 | 3 | 0 | 3 |
| ARID4A | NMU | 0.675935 | 5 | 0 | 5 |
| ARID4A | MAPK14 | 0.674102 | 3 | 0 | 3 |
| ARID4A | ANKRD13A | 0.66258 | 4 | 0 | 4 |
| ARID4A | PCP4 | 0.660977 | 4 | 0 | 4 |
| ARID4A | YY1AP1 | 0.660657 | 6 | 0 | 5 |
| ARID4A | TBCA | 0.656239 | 3 | 0 | 3 |
| ARID4A | MAST4 | 0.654851 | 4 | 0 | 4 |
| ARID4A | KRTAP5-10 | 0.653241 | 3 | 0 | 3 |
| ARID4A | NDUFC1 | 0.651581 | 3 | 0 | 3 |
| ARID4A | SERPINB13 | 0.651505 | 3 | 0 | 3 |
| ARID4A | LNX1 | 0.649226 | 5 | 0 | 4 |
| ARID4A | CIPC | 0.644768 | 6 | 0 | 5 |
| ARID4A | SPRR2B | 0.640934 | 3 | 0 | 3 |
| ARID4A | SH3BGRL2 | 0.637354 | 5 | 0 | 4 |
| ARID4A | TMEM45B | 0.637038 | 3 | 0 | 3 |
| ARID4A | HECTD1 | 0.634798 | 6 | 0 | 5 |
| ARID4A | KRT78 | 0.633232 | 5 | 0 | 4 |
| ARID4A | FAM214A | 0.630324 | 4 | 0 | 3 |
| ARID4A | SMIM14 | 0.628315 | 4 | 0 | 4 |
For details and further investigation, click here
