| Full name: adaptor related protein complex 5 subunit mu 1 | Alias Symbol: FLJ10813|MuD|mu5 | ||
| Type: protein-coding gene | Cytoband: 14q22.3 | ||
| Entrez ID: 55745 | HGNC ID: HGNC:20192 | Ensembl Gene: ENSG00000053770 | OMIM ID: 614368 |
| Drug and gene relationship at DGIdb | |||
Expression of AP5M1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AP5M1 | 55745 | 218139_s_at | -0.1333 | 0.8371 | |
| GSE20347 | AP5M1 | 55745 | 218139_s_at | -0.3352 | 0.0702 | |
| GSE23400 | AP5M1 | 55745 | 218139_s_at | 0.1633 | 0.1024 | |
| GSE26886 | AP5M1 | 55745 | 218139_s_at | -0.5340 | 0.0366 | |
| GSE29001 | AP5M1 | 55745 | 218139_s_at | 0.0405 | 0.9090 | |
| GSE38129 | AP5M1 | 55745 | 218139_s_at | -0.2024 | 0.1478 | |
| GSE45670 | AP5M1 | 55745 | 218139_s_at | -0.0587 | 0.7414 | |
| GSE53622 | AP5M1 | 55745 | 82433 | 0.0761 | 0.3041 | |
| GSE53624 | AP5M1 | 55745 | 71227 | -0.1107 | 0.0880 | |
| GSE63941 | AP5M1 | 55745 | 218139_s_at | -0.0347 | 0.9436 | |
| GSE77861 | AP5M1 | 55745 | 222531_s_at | -0.1832 | 0.7197 | |
| SRP007169 | AP5M1 | 55745 | RNAseq | 0.0222 | 0.9542 | |
| SRP008496 | AP5M1 | 55745 | RNAseq | 0.2413 | 0.2407 | |
| SRP064894 | AP5M1 | 55745 | RNAseq | -0.0006 | 0.9975 | |
| SRP133303 | AP5M1 | 55745 | RNAseq | 0.1094 | 0.5243 | |
| SRP159526 | AP5M1 | 55745 | RNAseq | -0.3105 | 0.1887 | |
| SRP193095 | AP5M1 | 55745 | RNAseq | -0.2936 | 0.0106 | |
| SRP219564 | AP5M1 | 55745 | RNAseq | -0.0559 | 0.8264 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AP5M1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of AP5M1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AP5M1 | 55745 | 8 | 3 | 19 | |
| GSE20123 | AP5M1 | 55745 | 8 | 3 | 19 | |
| GSE43470 | AP5M1 | 55745 | 8 | 2 | 33 | |
| GSE46452 | AP5M1 | 55745 | 16 | 3 | 40 | |
| GSE47630 | AP5M1 | 55745 | 11 | 10 | 19 | |
| GSE54993 | AP5M1 | 55745 | 3 | 8 | 59 | |
| GSE54994 | AP5M1 | 55745 | 19 | 4 | 30 | |
| GSE60625 | AP5M1 | 55745 | 0 | 2 | 9 | |
| GSE74703 | AP5M1 | 55745 | 7 | 2 | 27 | |
| GSE74704 | AP5M1 | 55745 | 3 | 2 | 15 | |
| TCGA | AP5M1 | 55745 | 32 | 14 | 50 |
Total number of gains: 115; Total number of losses: 53; Total Number of normals: 320.
Somatic mutations of AP5M1:
Generating mutation plots.
Highly correlated genes for AP5M1:
Showing top 20/148 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AP5M1 | ATAD1 | 0.72732 | 3 | 0 | 3 |
| AP5M1 | NDUFA12 | 0.723415 | 3 | 0 | 3 |
| AP5M1 | PRPF38A | 0.706044 | 3 | 0 | 3 |
| AP5M1 | SHOC2 | 0.703804 | 3 | 0 | 3 |
| AP5M1 | VPS26A | 0.690179 | 4 | 0 | 3 |
| AP5M1 | ARHGAP5 | 0.681662 | 5 | 0 | 5 |
| AP5M1 | GLUD2 | 0.675818 | 3 | 0 | 3 |
| AP5M1 | SNX4 | 0.653032 | 3 | 0 | 3 |
| AP5M1 | TRAPPC6B | 0.642149 | 5 | 0 | 4 |
| AP5M1 | CHCHD1 | 0.641562 | 3 | 0 | 3 |
| AP5M1 | ZNF543 | 0.639094 | 3 | 0 | 3 |
| AP5M1 | SPTBN2 | 0.638384 | 3 | 0 | 3 |
| AP5M1 | EGLN1 | 0.626008 | 3 | 0 | 3 |
| AP5M1 | ITGA2 | 0.614261 | 3 | 0 | 3 |
| AP5M1 | SNX13 | 0.611969 | 4 | 0 | 3 |
| AP5M1 | USP16 | 0.610598 | 4 | 0 | 3 |
| AP5M1 | PIK3CB | 0.610433 | 4 | 0 | 3 |
| AP5M1 | MRPL39 | 0.607115 | 4 | 0 | 3 |
| AP5M1 | GRSF1 | 0.606447 | 3 | 0 | 3 |
| AP5M1 | SLC25A3 | 0.604245 | 4 | 0 | 3 |
For details and further investigation, click here
