ATAD2B

 

Full name: ATPase family AAA domain containing 2B Alias Symbol: KIAA1240
Type: protein-coding gene Cytoband: 2p24.1-p23.3
Entrez ID: 54454 HGNC ID: HGNC:29230 Ensembl Gene: ENSG00000119778 OMIM ID: 615347
Drug and gene relationship at DGIdb

 

Expression of ATAD2B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ATAD2B 54454 213387_at 0.0594 0.9366
GSE20347 ATAD2B 54454 213387_at -0.0873 0.6451
GSE23400 ATAD2B 54454 213387_at 0.0793 0.4578
GSE26886 ATAD2B 54454 213387_at -0.4423 0.0481
GSE29001 ATAD2B 54454 213387_at 0.1638 0.4653
GSE38129 ATAD2B 54454 213387_at 0.2226 0.2675
GSE45670 ATAD2B 54454 213387_at 0.0351 0.8686
GSE53622 ATAD2B 54454 4382 -0.0554 0.5723
GSE53624 ATAD2B 54454 4382 -0.1721 0.0757
GSE63941 ATAD2B 54454 213387_at -0.5417 0.3698
GSE77861 ATAD2B 54454 213387_at -0.0945 0.7699
GSE97050 ATAD2B 54454 A_32_P191004 0.2154 0.3192
SRP007169 ATAD2B 54454 RNAseq -0.2663 0.3997
SRP008496 ATAD2B 54454 RNAseq -0.1014 0.5910
SRP064894 ATAD2B 54454 RNAseq -0.5680 0.0286
SRP133303 ATAD2B 54454 RNAseq -0.0467 0.7221
SRP159526 ATAD2B 54454 RNAseq -0.1357 0.5914
SRP193095 ATAD2B 54454 RNAseq -0.1930 0.0878
SRP219564 ATAD2B 54454 RNAseq -0.2323 0.5616
TCGA ATAD2B 54454 RNAseq 0.1020 0.0682

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by ATAD2B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ATAD2B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ATAD2B 54454 10 2 18
GSE20123 ATAD2B 54454 10 2 18
GSE43470 ATAD2B 54454 2 1 40
GSE46452 ATAD2B 54454 3 4 52
GSE47630 ATAD2B 54454 8 0 32
GSE54993 ATAD2B 54454 0 7 63
GSE54994 ATAD2B 54454 10 0 43
GSE60625 ATAD2B 54454 0 3 8
GSE74703 ATAD2B 54454 2 0 34
GSE74704 ATAD2B 54454 9 1 10
TCGA ATAD2B 54454 35 5 56

Total number of gains: 89; Total number of losses: 25; Total Number of normals: 374.  


 

Somatic mutations of ATAD2B:

 

Generating mutation plots.

 

Highly correlated genes for ATAD2B:

 

Showing top 20/104 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ATAD2BMAP3K40.699892303
ATAD2BUNC5CL0.646928303
ATAD2BRCAN30.638367303
ATAD2BC3orf380.623668303
ATAD2BTFAP2A0.617117403
ATAD2BMARS20.604454403
ATAD2BNAA200.604045505
ATAD2BALG60.599784504
ATAD2BEXOSC30.599137303
ATAD2BBROX0.598288303
ATAD2BFASTKD50.597897403
ATAD2BSUCLG10.593982303
ATAD2BMETAP10.58823504
ATAD2BMOSPD20.588189404
ATAD2BCYP4F30.587345303
ATAD2BBDH10.585097403
ATAD2BCXADR0.576264303
ATAD2BZNF7700.575572403
ATAD2BGGCT0.575175303
ATAD2BNOL60.572385303

For details and further investigation, click here