TRIP13

 

Full name: thyroid hormone receptor interactor 13 Alias Symbol: 16E1BP
Type: protein-coding gene Cytoband: 5p15.33
Entrez ID: 9319 HGNC ID: HGNC:12307 Ensembl Gene: ENSG00000071539 OMIM ID: 604507
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of TRIP13:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TRIP13 9319 204033_at 1.6787 0.0072
GSE20347 TRIP13 9319 204033_at 1.9698 0.0000
GSE23400 TRIP13 9319 204033_at 1.3015 0.0000
GSE26886 TRIP13 9319 204033_at 1.5348 0.0002
GSE29001 TRIP13 9319 204033_at 1.6262 0.0001
GSE38129 TRIP13 9319 204033_at 2.3382 0.0000
GSE45670 TRIP13 9319 204033_at 1.8092 0.0000
GSE53622 TRIP13 9319 62283 2.2454 0.0000
GSE53624 TRIP13 9319 151375 2.0603 0.0000
GSE63941 TRIP13 9319 204033_at 2.8286 0.0003
GSE77861 TRIP13 9319 204033_at 1.4754 0.0096
GSE97050 TRIP13 9319 A_33_P3407256 2.4221 0.1297
SRP007169 TRIP13 9319 RNAseq 2.1787 0.0000
SRP008496 TRIP13 9319 RNAseq 2.0427 0.0000
SRP064894 TRIP13 9319 RNAseq 1.4025 0.0000
SRP133303 TRIP13 9319 RNAseq 1.9524 0.0000
SRP159526 TRIP13 9319 RNAseq 2.1668 0.0000
SRP193095 TRIP13 9319 RNAseq 1.5067 0.0000
SRP219564 TRIP13 9319 RNAseq 2.2867 0.0043
TCGA TRIP13 9319 RNAseq 1.2085 0.0000

Upregulated datasets: 19; Downregulated datasets: 0.  

 

Survival by TRIP13 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TRIP13:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TRIP13 9319 13 1 16
GSE20123 TRIP13 9319 13 1 16
GSE43470 TRIP13 9319 17 1 25
GSE46452 TRIP13 9319 6 22 31
GSE47630 TRIP13 9319 8 11 21
GSE54993 TRIP13 9319 5 6 59
GSE54994 TRIP13 9319 29 1 23
GSE60625 TRIP13 9319 0 0 11
GSE74703 TRIP13 9319 14 0 22
GSE74704 TRIP13 9319 11 0 9
TCGA TRIP13 9319 60 4 32

Total number of gains: 176; Total number of losses: 47; Total Number of normals: 265.  

 

Somatic mutations of TRIP13:

 

Generating mutation plots.

 

Highly correlated genes for TRIP13:

 

Showing top 20/1975 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TRIP13CENPF0.85420512012
TRIP13NCAPH0.847199909
TRIP13UBE2C0.83667513012
TRIP13KIF140.83549413013
TRIP13AURKB0.83511913012
TRIP13ECT20.83428712012
TRIP13NEK20.83406713012
TRIP13KIF4A0.83344512011
TRIP13KNSTRN0.832307707
TRIP13RAD510.82989111011
TRIP13TPX20.82951613012
TRIP13CDC60.829184909
TRIP13CDKN30.82809112012
TRIP13CDK10.82798512012
TRIP13MTFR20.827383707
TRIP13MYBL20.82634512012
TRIP13CDC450.82482412012
TRIP13MCM40.82390713013
TRIP13KIF2C0.82324113012
TRIP13GINS10.82265712012

For details and further investigation, click here