| Full name: potassium voltage-gated channel modifier subfamily G member 3 | Alias Symbol: Kv6.3 | ||
| Type: protein-coding gene | Cytoband: 2p21 | ||
| Entrez ID: 170850 | HGNC ID: HGNC:18306 | Ensembl Gene: ENSG00000171126 | OMIM ID: 606767 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNG3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNG3 | 170850 | 1552897_a_at | 1.3670 | 0.0792 | |
| GSE26886 | KCNG3 | 170850 | 1552898_a_at | 0.1383 | 0.3126 | |
| GSE45670 | KCNG3 | 170850 | 1552897_a_at | 0.4406 | 0.1348 | |
| GSE53622 | KCNG3 | 170850 | 89672 | 1.7132 | 0.0000 | |
| GSE53624 | KCNG3 | 170850 | 89672 | 2.3534 | 0.0000 | |
| GSE63941 | KCNG3 | 170850 | 1552897_a_at | 1.0489 | 0.2216 | |
| GSE77861 | KCNG3 | 170850 | 1552898_a_at | -0.0229 | 0.8014 | |
| TCGA | KCNG3 | 170850 | RNAseq | 2.6807 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by KCNG3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCNG3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNG3 | 170850 | 12 | 1 | 17 | |
| GSE20123 | KCNG3 | 170850 | 11 | 1 | 18 | |
| GSE43470 | KCNG3 | 170850 | 3 | 0 | 40 | |
| GSE46452 | KCNG3 | 170850 | 1 | 4 | 54 | |
| GSE47630 | KCNG3 | 170850 | 7 | 0 | 33 | |
| GSE54993 | KCNG3 | 170850 | 0 | 5 | 65 | |
| GSE54994 | KCNG3 | 170850 | 10 | 2 | 41 | |
| GSE60625 | KCNG3 | 170850 | 0 | 3 | 8 | |
| GSE74703 | KCNG3 | 170850 | 3 | 0 | 33 | |
| GSE74704 | KCNG3 | 170850 | 10 | 1 | 9 | |
| TCGA | KCNG3 | 170850 | 35 | 2 | 59 |
Total number of gains: 92; Total number of losses: 19; Total Number of normals: 377.
Somatic mutations of KCNG3:
Generating mutation plots.
Highly correlated genes for KCNG3:
Showing top 20/113 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNG3 | JPH1 | 0.694967 | 3 | 0 | 3 |
| KCNG3 | RBFOX1 | 0.687248 | 3 | 0 | 3 |
| KCNG3 | BIRC7 | 0.674771 | 3 | 0 | 3 |
| KCNG3 | HOXD13 | 0.642287 | 4 | 0 | 4 |
| KCNG3 | TFRC | 0.638262 | 4 | 0 | 4 |
| KCNG3 | ERF | 0.628442 | 3 | 0 | 3 |
| KCNG3 | ZIC5 | 0.615482 | 3 | 0 | 3 |
| KCNG3 | LINGO1 | 0.614736 | 3 | 0 | 3 |
| KCNG3 | DESI2 | 0.609181 | 4 | 0 | 4 |
| KCNG3 | PFN2 | 0.608374 | 4 | 0 | 4 |
| KCNG3 | POLR2H | 0.606414 | 5 | 0 | 3 |
| KCNG3 | C10orf91 | 0.604922 | 3 | 0 | 3 |
| KCNG3 | LIMK1 | 0.60359 | 4 | 0 | 3 |
| KCNG3 | GMPS | 0.600573 | 5 | 0 | 5 |
| KCNG3 | CCDC114 | 0.599223 | 3 | 0 | 3 |
| KCNG3 | TMEM52 | 0.598107 | 3 | 0 | 3 |
| KCNG3 | PTDSS1 | 0.59575 | 4 | 0 | 4 |
| KCNG3 | CLCN2 | 0.594788 | 7 | 0 | 6 |
| KCNG3 | LRP12 | 0.591257 | 4 | 0 | 4 |
| KCNG3 | HEY1 | 0.591044 | 3 | 0 | 3 |
For details and further investigation, click here
