SLC2A1

 

Full name: solute carrier family 2 member 1 Alias Symbol: DYT18|DYT9
Type: protein-coding gene Cytoband: 1p34.2
Entrez ID: 6513 HGNC ID: HGNC:11005 Ensembl Gene: ENSG00000117394 OMIM ID: 138140
Drug and gene relationship at DGIdb
Screen Evidence:

 

SLC2A1 involved pathways:

KEGG pathway Description View
hsa04066HIF-1 signaling pathway
hsa04919Thyroid hormone signaling pathway
hsa04920Adipocytokine signaling pathway
hsa05166HTLV-I infection
hsa05200Pathways in cancer
hsa05211Renal cell carcinoma

 

Expression of SLC2A1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SLC2A1 6513 201250_s_at 1.1362 0.1341
GSE20347 SLC2A1 6513 201250_s_at 1.3456 0.0000
GSE23400 SLC2A1 6513 201250_s_at 1.1639 0.0000
GSE26886 SLC2A1 6513 201250_s_at 1.6695 0.0000
GSE29001 SLC2A1 6513 201250_s_at 1.0830 0.0350
GSE38129 SLC2A1 6513 201250_s_at 1.9158 0.0000
GSE45670 SLC2A1 6513 201250_s_at 1.7543 0.0001
GSE53622 SLC2A1 6513 94318 1.6455 0.0000
GSE53624 SLC2A1 6513 94318 1.6704 0.0000
GSE63941 SLC2A1 6513 201250_s_at 0.9371 0.1720
GSE77861 SLC2A1 6513 201250_s_at 1.2649 0.0624
GSE97050 SLC2A1 6513 A_23_P571 1.6337 0.0959
SRP007169 SLC2A1 6513 RNAseq 2.0487 0.0000
SRP008496 SLC2A1 6513 RNAseq 1.9941 0.0000
SRP064894 SLC2A1 6513 RNAseq 1.2846 0.0044
SRP133303 SLC2A1 6513 RNAseq 2.0848 0.0000
SRP159526 SLC2A1 6513 RNAseq 0.9304 0.1161
SRP193095 SLC2A1 6513 RNAseq 1.9209 0.0000
SRP219564 SLC2A1 6513 RNAseq 0.5525 0.5673
TCGA SLC2A1 6513 RNAseq 0.7899 0.0000

Upregulated datasets: 13; Downregulated datasets: 0.  

 

Survival by SLC2A1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SLC2A1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLC2A1 6513 4 3 23
GSE20123 SLC2A1 6513 4 2 24
GSE43470 SLC2A1 6513 7 2 34
GSE46452 SLC2A1 6513 3 1 55
GSE47630 SLC2A1 6513 9 2 29
GSE54993 SLC2A1 6513 0 2 68
GSE54994 SLC2A1 6513 14 2 37
GSE60625 SLC2A1 6513 0 0 11
GSE74703 SLC2A1 6513 6 1 29
GSE74704 SLC2A1 6513 2 0 18
TCGA SLC2A1 6513 13 16 67

Total number of gains: 62; Total number of losses: 31; Total Number of normals: 395.  

 

Somatic mutations of SLC2A1:

 

Generating mutation plots.

 

Highly correlated genes for SLC2A1:

 

Showing top 20/1281 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLC2A1KRT170.768215404
SLC2A1CDH30.7404910010
SLC2A1PTHLH0.73085712012
SLC2A1CYP27C10.728514504
SLC2A1PPIA0.725532303
SLC2A1ZNF1140.725116403
SLC2A1SLC7A50.723332909
SLC2A1HPRT10.72125909
SLC2A1XPR10.717586606
SLC2A1COL7A10.71682311010
SLC2A1LAMC20.70615112011
SLC2A1WDR660.705294807
SLC2A1NEK60.702759303
SLC2A1NDRG10.70190612012
SLC2A1MSRB10.697864403
SLC2A1BNC10.69711412012
SLC2A1MMP10.69664511011
SLC2A1BOP10.696468303
SLC2A1FSCN10.69570613010
SLC2A1TRIP130.6954851009

For details and further investigation, click here