| Full name: keratin 14 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 3861 | HGNC ID: HGNC:6416 | Ensembl Gene: ENSG00000186847 | OMIM ID: 148066 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT14 | 3861 | 209351_at | 0.7022 | 0.5609 | |
| GSE20347 | KRT14 | 3861 | 209351_at | 0.6148 | 0.4116 | |
| GSE23400 | KRT14 | 3861 | 209351_at | 1.2728 | 0.0002 | |
| GSE26886 | KRT14 | 3861 | 209351_at | 0.5742 | 0.5242 | |
| GSE29001 | KRT14 | 3861 | 209351_at | 1.0033 | 0.3694 | |
| GSE38129 | KRT14 | 3861 | 209351_at | 1.8748 | 0.0133 | |
| GSE45670 | KRT14 | 3861 | 209351_at | 2.7263 | 0.0000 | |
| GSE53622 | KRT14 | 3861 | 43893 | 1.0859 | 0.0001 | |
| GSE53624 | KRT14 | 3861 | 43893 | 0.4330 | 0.0006 | |
| GSE63941 | KRT14 | 3861 | 209351_at | 3.2927 | 0.2278 | |
| GSE77861 | KRT14 | 3861 | 209351_at | 1.1719 | 0.0398 | |
| GSE97050 | KRT14 | 3861 | A_33_P3345534 | 2.7504 | 0.1557 | |
| SRP007169 | KRT14 | 3861 | RNAseq | 2.3042 | 0.0000 | |
| SRP008496 | KRT14 | 3861 | RNAseq | 1.8480 | 0.0004 | |
| SRP064894 | KRT14 | 3861 | RNAseq | 2.7329 | 0.0000 | |
| SRP133303 | KRT14 | 3861 | RNAseq | 3.6938 | 0.0000 | |
| SRP159526 | KRT14 | 3861 | RNAseq | 1.9387 | 0.0115 | |
| TCGA | KRT14 | 3861 | RNAseq | 1.4634 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by KRT14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT14 | 3861 | 6 | 2 | 22 | |
| GSE20123 | KRT14 | 3861 | 6 | 2 | 22 | |
| GSE43470 | KRT14 | 3861 | 1 | 2 | 40 | |
| GSE46452 | KRT14 | 3861 | 34 | 0 | 25 | |
| GSE47630 | KRT14 | 3861 | 8 | 1 | 31 | |
| GSE54993 | KRT14 | 3861 | 3 | 4 | 63 | |
| GSE54994 | KRT14 | 3861 | 8 | 5 | 40 | |
| GSE60625 | KRT14 | 3861 | 4 | 0 | 7 | |
| GSE74703 | KRT14 | 3861 | 1 | 1 | 34 | |
| GSE74704 | KRT14 | 3861 | 4 | 1 | 15 | |
| TCGA | KRT14 | 3861 | 23 | 7 | 66 |
Total number of gains: 98; Total number of losses: 25; Total Number of normals: 365.
Somatic mutations of KRT14:
Generating mutation plots.
Highly correlated genes for KRT14:
Showing top 20/436 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT14 | KRT17 | 0.828874 | 4 | 0 | 4 |
| KRT14 | KRT16 | 0.736959 | 13 | 0 | 12 |
| KRT14 | KRT6C | 0.712783 | 4 | 0 | 4 |
| KRT14 | KRT5 | 0.704521 | 10 | 0 | 9 |
| KRT14 | BNC1 | 0.701506 | 13 | 0 | 13 |
| KRT14 | TENM2 | 0.697254 | 5 | 0 | 4 |
| KRT14 | WDR54 | 0.690773 | 3 | 0 | 3 |
| KRT14 | KRT6A | 0.679899 | 11 | 0 | 9 |
| KRT14 | CDH3 | 0.678107 | 10 | 0 | 8 |
| KRT14 | BLACAT1 | 0.663102 | 3 | 0 | 3 |
| KRT14 | RCC2 | 0.662145 | 4 | 0 | 3 |
| KRT14 | MZB1 | 0.65748 | 3 | 0 | 3 |
| KRT14 | WNT7B | 0.650611 | 8 | 0 | 6 |
| KRT14 | TP63 | 0.650153 | 10 | 0 | 9 |
| KRT14 | STARD4 | 0.648863 | 4 | 0 | 3 |
| KRT14 | SLC2A1 | 0.648161 | 12 | 0 | 10 |
| KRT14 | PPP1R14C | 0.646467 | 8 | 0 | 6 |
| KRT14 | SLC7A5 | 0.645846 | 10 | 0 | 9 |
| KRT14 | NIPAL4 | 0.631067 | 5 | 0 | 5 |
| KRT14 | DCBLD1 | 0.630334 | 6 | 0 | 4 |
For details and further investigation, click here
