KRT17

 

Full name: keratin 17 Alias Symbol: 
Type: protein-coding gene Cytoband: 17q21.2
Entrez ID: 3872 HGNC ID: HGNC:6427 Ensembl Gene: ENSG00000128422 OMIM ID: 148069
Drug and gene relationship at DGIdb

 

Expression of KRT17:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 KRT17 3872 20389 1.7468 0.0000
GSE53624 KRT17 3872 20389 1.2558 0.0000
GSE97050 KRT17 3872 A_23_P96158 3.4608 0.0750
SRP007169 KRT17 3872 RNAseq 2.6568 0.0005
SRP008496 KRT17 3872 RNAseq 2.7139 0.0000
SRP064894 KRT17 3872 RNAseq 3.0050 0.0000
SRP133303 KRT17 3872 RNAseq 4.4698 0.0000
SRP159526 KRT17 3872 RNAseq 4.2259 0.0000
SRP219564 KRT17 3872 RNAseq 4.1898 0.0001
TCGA KRT17 3872 RNAseq 1.7256 0.0000

Upregulated datasets: 9; Downregulated datasets: 0.  

 

Survival by KRT17 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KRT17:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KRT17 3872 6 2 22
GSE20123 KRT17 3872 6 2 22
GSE43470 KRT17 3872 1 2 40
GSE46452 KRT17 3872 34 0 25
GSE47630 KRT17 3872 8 1 31
GSE54993 KRT17 3872 3 4 63
GSE54994 KRT17 3872 8 5 40
GSE60625 KRT17 3872 4 0 7
GSE74703 KRT17 3872 1 1 34
GSE74704 KRT17 3872 4 1 15
TCGA KRT17 3872 23 7 66

Total number of gains: 98; Total number of losses: 25; Total Number of normals: 365.  

 

Somatic mutations of KRT17:

 

Generating mutation plots.

 

Highly correlated genes for KRT17:

 

Showing top 20/87 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KRT17KRT140.828874404
KRT17WNT7B0.806774303
KRT17KRT160.789004404
KRT17SLC2A10.768215404
KRT17TP630.752087403
KRT17COL7A10.735002303
KRT17FERMT10.730992303
KRT17KRT6A0.725599404
KRT17PTHLH0.701509404
KRT17BNC10.691235403
KRT17FSCN10.688428403
KRT17ATP1B30.680241303
KRT17S100A20.675529404
KRT17PPP1R14B0.674913303
KRT17FOXE10.671408303
KRT17LAMC20.6701403
KRT17NDRG10.668135404
KRT17PPIA0.662968303
KRT17ADAM120.658988303
KRT17DSC30.657625403

For details and further investigation, click here