IFI35

 

Full name: interferon induced protein 35 Alias Symbol: IFP35
Type: protein-coding gene Cytoband: 17q21.31
Entrez ID: 3430 HGNC ID: HGNC:5399 Ensembl Gene: ENSG00000068079 OMIM ID: 600735
Drug and gene relationship at DGIdb

 

Expression of IFI35:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 IFI35 3430 209417_s_at 0.7333 0.3926
GSE20347 IFI35 3430 209417_s_at 1.3562 0.0000
GSE23400 IFI35 3430 209417_s_at 1.0856 0.0000
GSE26886 IFI35 3430 209417_s_at 1.3756 0.0017
GSE29001 IFI35 3430 209417_s_at 1.7020 0.0001
GSE38129 IFI35 3430 209417_s_at 1.0909 0.0002
GSE45670 IFI35 3430 209417_s_at 1.2769 0.0005
GSE53622 IFI35 3430 9775 1.2412 0.0000
GSE53624 IFI35 3430 9775 1.5496 0.0000
GSE63941 IFI35 3430 209417_s_at 0.6007 0.4788
GSE77861 IFI35 3430 209417_s_at 0.6222 0.0160
GSE97050 IFI35 3430 A_23_P152782 0.5157 0.2537
SRP007169 IFI35 3430 RNAseq 2.5388 0.0000
SRP008496 IFI35 3430 RNAseq 3.2355 0.0000
SRP064894 IFI35 3430 RNAseq 2.0254 0.0000
SRP133303 IFI35 3430 RNAseq 1.2785 0.0000
SRP159526 IFI35 3430 RNAseq 0.5561 0.2921
SRP193095 IFI35 3430 RNAseq 1.1115 0.0001
SRP219564 IFI35 3430 RNAseq 1.4841 0.0338
TCGA IFI35 3430 RNAseq 0.3878 0.0005

Upregulated datasets: 14; Downregulated datasets: 0.  

 

Survival by IFI35 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of IFI35:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 IFI35 3430 6 2 22
GSE20123 IFI35 3430 6 2 22
GSE43470 IFI35 3430 1 2 40
GSE46452 IFI35 3430 34 0 25
GSE47630 IFI35 3430 8 1 31
GSE54993 IFI35 3430 3 4 63
GSE54994 IFI35 3430 8 5 40
GSE60625 IFI35 3430 4 0 7
GSE74703 IFI35 3430 1 1 34
GSE74704 IFI35 3430 4 1 15
TCGA IFI35 3430 22 7 67

Total number of gains: 97; Total number of losses: 25; Total Number of normals: 366.  

 

Somatic mutations of IFI35:

 

Generating mutation plots.

 

Highly correlated genes for IFI35:

 

Showing top 20/1484 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
IFI35IFITM10.80753610010
IFI35IFI60.80561813013
IFI35UBE2L60.80250913013
IFI35USP410.801041303
IFI35IFI440.7874713013
IFI35DDX600.7854413013
IFI35IFI44L0.77664513013
IFI35CMPK20.775834807
IFI35ISG150.76776513012
IFI35HERC50.76726913012
IFI35IFIT10.76365513013
IFI35IFIT30.76235113012
IFI35ARPC1B0.75871311010
IFI35FCGR3A0.753378303
IFI35USP180.74074413013
IFI35IFITM30.73924313013
IFI35RSAD20.73882213012
IFI35EPSTI10.737406808
IFI35PSMB90.73528912011
IFI35HLA-F0.73471113013

For details and further investigation, click here