BTN3A3

 

Full name: butyrophilin subfamily 3 member A3 Alias Symbol: BTF3|BTN3.3
Type: protein-coding gene Cytoband: 6p22.2
Entrez ID: 10384 HGNC ID: HGNC:1140 Ensembl Gene: ENSG00000111801 OMIM ID: 613595
Drug and gene relationship at DGIdb

 

Expression of BTN3A3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BTN3A3 10384 204821_at 0.4646 0.6391
GSE20347 BTN3A3 10384 204821_at 0.4582 0.1561
GSE23400 BTN3A3 10384 204821_at 0.4074 0.0000
GSE26886 BTN3A3 10384 204821_at 0.3529 0.4875
GSE29001 BTN3A3 10384 204821_at 0.7356 0.0126
GSE38129 BTN3A3 10384 204821_at 0.2732 0.3514
GSE45670 BTN3A3 10384 204821_at 0.6800 0.0770
GSE63941 BTN3A3 10384 204821_at -1.3214 0.2407
GSE77861 BTN3A3 10384 204821_at -0.1668 0.5130
SRP007169 BTN3A3 10384 RNAseq 0.2676 0.6139
SRP008496 BTN3A3 10384 RNAseq 0.3155 0.3915
SRP064894 BTN3A3 10384 RNAseq 0.6088 0.0062
SRP133303 BTN3A3 10384 RNAseq 0.3390 0.1603
SRP159526 BTN3A3 10384 RNAseq -0.0196 0.9645
SRP193095 BTN3A3 10384 RNAseq 0.1141 0.5979
SRP219564 BTN3A3 10384 RNAseq 1.1439 0.0152
TCGA BTN3A3 10384 RNAseq 0.1907 0.1033

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by BTN3A3 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of BTN3A3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BTN3A3 10384 4 2 24
GSE20123 BTN3A3 10384 4 2 24
GSE43470 BTN3A3 10384 5 0 38
GSE46452 BTN3A3 10384 1 9 49
GSE47630 BTN3A3 10384 8 5 27
GSE54993 BTN3A3 10384 1 1 68
GSE54994 BTN3A3 10384 10 4 39
GSE60625 BTN3A3 10384 0 1 10
GSE74703 BTN3A3 10384 5 0 31
GSE74704 BTN3A3 10384 0 1 19
TCGA BTN3A3 10384 15 21 60

Total number of gains: 53; Total number of losses: 46; Total Number of normals: 389.  


 

Somatic mutations of BTN3A3:

 

Generating mutation plots.

 

Highly correlated genes for BTN3A3:

 

Showing top 20/219 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BTN3A3BTN3A20.78625810010
BTN3A3PSMB90.76465410010
BTN3A3BTN3A10.7555261009
BTN3A3HLA-F0.735412908
BTN3A3PSMB80.73369710010
BTN3A3PSMB8-AS10.700029404
BTN3A3HLA-B0.6947421009
BTN3A3HLA-A0.693867908
BTN3A3TAP10.6830791009
BTN3A3NMI0.66940210010
BTN3A3PSMB100.66504908
BTN3A3EPSTI10.65862403
BTN3A3HLA-C0.6575771008
BTN3A3BTN2A10.653923908
BTN3A3PARP140.652982504
BTN3A3ANKFY10.652218303
BTN3A3IFIT20.649284504
BTN3A3GBP10.646029908
BTN3A3HLA-G0.644245906
BTN3A3PARP90.63943606

For details and further investigation, click here