| Full name: COMM domain containing 10 | Alias Symbol: PTD002 | ||
| Type: protein-coding gene | Cytoband: 5q23.1 | ||
| Entrez ID: 51397 | HGNC ID: HGNC:30201 | Ensembl Gene: ENSG00000145781 | OMIM ID: 616704 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COMMD10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COMMD10 | 51397 | 218439_s_at | -0.2512 | 0.6752 | |
| GSE20347 | COMMD10 | 51397 | 218439_s_at | -0.2226 | 0.2489 | |
| GSE23400 | COMMD10 | 51397 | 218439_s_at | -0.0359 | 0.6258 | |
| GSE26886 | COMMD10 | 51397 | 222637_at | -0.4988 | 0.0817 | |
| GSE29001 | COMMD10 | 51397 | 218439_s_at | 0.1209 | 0.6875 | |
| GSE38129 | COMMD10 | 51397 | 218439_s_at | -0.0873 | 0.6671 | |
| GSE45670 | COMMD10 | 51397 | 218439_s_at | -0.3820 | 0.0149 | |
| GSE53622 | COMMD10 | 51397 | 91861 | -0.2146 | 0.0101 | |
| GSE53624 | COMMD10 | 51397 | 91861 | -0.3187 | 0.0018 | |
| GSE63941 | COMMD10 | 51397 | 218439_s_at | 0.7619 | 0.1478 | |
| GSE77861 | COMMD10 | 51397 | 218439_s_at | -0.5157 | 0.1031 | |
| GSE97050 | COMMD10 | 51397 | A_23_P252403 | -0.1574 | 0.5613 | |
| SRP007169 | COMMD10 | 51397 | RNAseq | -1.6827 | 0.0001 | |
| SRP008496 | COMMD10 | 51397 | RNAseq | -1.4310 | 0.0000 | |
| SRP064894 | COMMD10 | 51397 | RNAseq | -0.3629 | 0.0302 | |
| SRP133303 | COMMD10 | 51397 | RNAseq | 0.1771 | 0.2350 | |
| SRP159526 | COMMD10 | 51397 | RNAseq | -0.3790 | 0.3778 | |
| SRP193095 | COMMD10 | 51397 | RNAseq | -0.5594 | 0.0000 | |
| SRP219564 | COMMD10 | 51397 | RNAseq | -0.3846 | 0.2836 | |
| TCGA | COMMD10 | 51397 | RNAseq | -0.1877 | 0.0021 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by COMMD10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COMMD10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COMMD10 | 51397 | 1 | 13 | 16 | |
| GSE20123 | COMMD10 | 51397 | 1 | 13 | 16 | |
| GSE43470 | COMMD10 | 51397 | 3 | 8 | 32 | |
| GSE46452 | COMMD10 | 51397 | 0 | 28 | 31 | |
| GSE47630 | COMMD10 | 51397 | 0 | 21 | 19 | |
| GSE54993 | COMMD10 | 51397 | 9 | 1 | 60 | |
| GSE54994 | COMMD10 | 51397 | 1 | 16 | 36 | |
| GSE60625 | COMMD10 | 51397 | 0 | 0 | 11 | |
| GSE74703 | COMMD10 | 51397 | 2 | 6 | 28 | |
| GSE74704 | COMMD10 | 51397 | 1 | 7 | 12 | |
| TCGA | COMMD10 | 51397 | 2 | 43 | 51 |
Total number of gains: 20; Total number of losses: 156; Total Number of normals: 312.
Somatic mutations of COMMD10:
Generating mutation plots.
Highly correlated genes for COMMD10:
Showing top 20/432 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COMMD10 | TRIM61 | 0.819744 | 3 | 0 | 3 |
| COMMD10 | RAB18 | 0.818581 | 3 | 0 | 3 |
| COMMD10 | LEPROT | 0.773975 | 5 | 0 | 5 |
| COMMD10 | KBTBD4 | 0.730908 | 3 | 0 | 3 |
| COMMD10 | PPP4R1 | 0.729639 | 4 | 0 | 4 |
| COMMD10 | ARL4A | 0.727819 | 3 | 0 | 3 |
| COMMD10 | ST13 | 0.726502 | 4 | 0 | 4 |
| COMMD10 | RIOK2 | 0.720484 | 5 | 0 | 5 |
| COMMD10 | IQGAP1 | 0.717318 | 3 | 0 | 3 |
| COMMD10 | TRERF1 | 0.715373 | 3 | 0 | 3 |
| COMMD10 | E2F8 | 0.713473 | 3 | 0 | 3 |
| COMMD10 | JMJD1C | 0.713256 | 3 | 0 | 3 |
| COMMD10 | FPGT | 0.712217 | 3 | 0 | 3 |
| COMMD10 | PDZD11 | 0.710067 | 4 | 0 | 3 |
| COMMD10 | C11orf54 | 0.702629 | 4 | 0 | 3 |
| COMMD10 | ARPC5 | 0.701567 | 3 | 0 | 3 |
| COMMD10 | IRAK2 | 0.700383 | 3 | 0 | 3 |
| COMMD10 | IFNGR2 | 0.696012 | 3 | 0 | 3 |
| COMMD10 | NSMCE4A | 0.692567 | 3 | 0 | 3 |
| COMMD10 | COG5 | 0.691845 | 4 | 0 | 4 |
For details and further investigation, click here
