| Full name: leukocyte associated immunoglobulin like receptor 2 | Alias Symbol: CD306 | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 3904 | HGNC ID: HGNC:6478 | Ensembl Gene: ENSG00000167618 | OMIM ID: 602993 |
| Drug and gene relationship at DGIdb | |||
Expression of LAIR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LAIR2 | 3904 | 207509_s_at | 0.5933 | 0.5202 | |
| GSE20347 | LAIR2 | 3904 | 207509_s_at | 0.3831 | 0.0003 | |
| GSE23400 | LAIR2 | 3904 | 207509_s_at | 0.1011 | 0.0292 | |
| GSE26886 | LAIR2 | 3904 | 207509_s_at | 0.3008 | 0.1483 | |
| GSE29001 | LAIR2 | 3904 | 207509_s_at | 0.2083 | 0.3152 | |
| GSE38129 | LAIR2 | 3904 | 207509_s_at | 0.5357 | 0.0002 | |
| GSE45670 | LAIR2 | 3904 | 207509_s_at | 0.6391 | 0.0038 | |
| GSE53622 | LAIR2 | 3904 | 78868 | 0.7444 | 0.0000 | |
| GSE53624 | LAIR2 | 3904 | 155095 | 1.5543 | 0.0000 | |
| GSE63941 | LAIR2 | 3904 | 207509_s_at | 0.4100 | 0.0838 | |
| GSE77861 | LAIR2 | 3904 | 207509_s_at | 0.0347 | 0.8508 | |
| GSE97050 | LAIR2 | 3904 | A_23_P209129 | 0.2696 | 0.2569 | |
| SRP133303 | LAIR2 | 3904 | RNAseq | 1.3364 | 0.0018 | |
| SRP219564 | LAIR2 | 3904 | RNAseq | 2.9143 | 0.0000 | |
| TCGA | LAIR2 | 3904 | RNAseq | 3.1920 | 0.0003 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by LAIR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LAIR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LAIR2 | 3904 | 3 | 4 | 23 | |
| GSE20123 | LAIR2 | 3904 | 3 | 3 | 24 | |
| GSE43470 | LAIR2 | 3904 | 2 | 11 | 30 | |
| GSE46452 | LAIR2 | 3904 | 45 | 1 | 13 | |
| GSE47630 | LAIR2 | 3904 | 8 | 6 | 26 | |
| GSE54993 | LAIR2 | 3904 | 17 | 4 | 49 | |
| GSE54994 | LAIR2 | 3904 | 4 | 13 | 36 | |
| GSE60625 | LAIR2 | 3904 | 9 | 0 | 2 | |
| GSE74703 | LAIR2 | 3904 | 2 | 7 | 27 | |
| GSE74704 | LAIR2 | 3904 | 3 | 1 | 16 | |
| TCGA | LAIR2 | 3904 | 19 | 14 | 63 |
Total number of gains: 115; Total number of losses: 64; Total Number of normals: 309.
Somatic mutations of LAIR2:
Generating mutation plots.
Highly correlated genes for LAIR2:
Showing top 20/213 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LAIR2 | PIK3AP1 | 0.738173 | 3 | 0 | 3 |
| LAIR2 | MS4A4E | 0.730341 | 3 | 0 | 3 |
| LAIR2 | SLC8A3 | 0.708878 | 4 | 0 | 4 |
| LAIR2 | PNPLA2 | 0.70748 | 4 | 0 | 4 |
| LAIR2 | CABP4 | 0.696649 | 4 | 0 | 4 |
| LAIR2 | ATP6V0D2 | 0.695867 | 3 | 0 | 3 |
| LAIR2 | PHGR1 | 0.688725 | 3 | 0 | 3 |
| LAIR2 | GLB1 | 0.667848 | 3 | 0 | 3 |
| LAIR2 | MMP23B | 0.659979 | 3 | 0 | 3 |
| LAIR2 | KCNIP2-AS1 | 0.657061 | 3 | 0 | 3 |
| LAIR2 | LILRB1 | 0.645282 | 8 | 0 | 7 |
| LAIR2 | CCDC34 | 0.637256 | 3 | 0 | 3 |
| LAIR2 | CBX8 | 0.634485 | 5 | 0 | 4 |
| LAIR2 | SCGN | 0.634058 | 3 | 0 | 3 |
| LAIR2 | METTL7B | 0.632372 | 3 | 0 | 3 |
| LAIR2 | SIGLEC10 | 0.632225 | 6 | 0 | 5 |
| LAIR2 | FIZ1 | 0.631666 | 3 | 0 | 3 |
| LAIR2 | CCNO | 0.628679 | 3 | 0 | 3 |
| LAIR2 | LAIR1 | 0.626671 | 7 | 0 | 5 |
| LAIR2 | NXPH3 | 0.62622 | 3 | 0 | 3 |
For details and further investigation, click here
