| Full name: chromosome 12 open reading frame 76 | Alias Symbol: FLJ40142 | ||
| Type: protein-coding gene | Cytoband: 12q24.11 | ||
| Entrez ID: 400073 | HGNC ID: HGNC:33790 | Ensembl Gene: ENSG00000174456 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C12orf76:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C12orf76 | 400073 | 226583_at | 0.1866 | 0.6051 | |
| GSE26886 | C12orf76 | 400073 | 226583_at | 0.6509 | 0.0017 | |
| GSE45670 | C12orf76 | 400073 | 226583_at | 0.2881 | 0.0098 | |
| GSE53622 | C12orf76 | 400073 | 42568 | 0.4788 | 0.0000 | |
| GSE53624 | C12orf76 | 400073 | 42568 | 0.5889 | 0.0000 | |
| GSE63941 | C12orf76 | 400073 | 226583_at | 0.3716 | 0.3296 | |
| GSE77861 | C12orf76 | 400073 | 226583_at | 0.2972 | 0.0426 | |
| GSE97050 | C12orf76 | 400073 | A_23_P410312 | 0.0197 | 0.9395 | |
| SRP007169 | C12orf76 | 400073 | RNAseq | 1.7147 | 0.0089 | |
| SRP008496 | C12orf76 | 400073 | RNAseq | 1.5679 | 0.0001 | |
| SRP064894 | C12orf76 | 400073 | RNAseq | 0.7232 | 0.0000 | |
| SRP133303 | C12orf76 | 400073 | RNAseq | 0.2420 | 0.1763 | |
| SRP159526 | C12orf76 | 400073 | RNAseq | 0.8109 | 0.0020 | |
| SRP193095 | C12orf76 | 400073 | RNAseq | 0.3207 | 0.0035 | |
| SRP219564 | C12orf76 | 400073 | RNAseq | 0.4921 | 0.0771 | |
| TCGA | C12orf76 | 400073 | RNAseq | 0.3256 | 0.0005 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by C12orf76 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C12orf76:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C12orf76 | 400073 | 5 | 3 | 22 | |
| GSE20123 | C12orf76 | 400073 | 5 | 3 | 22 | |
| GSE43470 | C12orf76 | 400073 | 2 | 1 | 40 | |
| GSE46452 | C12orf76 | 400073 | 9 | 1 | 49 | |
| GSE47630 | C12orf76 | 400073 | 9 | 1 | 30 | |
| GSE54993 | C12orf76 | 400073 | 0 | 5 | 65 | |
| GSE54994 | C12orf76 | 400073 | 4 | 3 | 46 | |
| GSE60625 | C12orf76 | 400073 | 0 | 0 | 11 | |
| GSE74703 | C12orf76 | 400073 | 2 | 0 | 34 | |
| GSE74704 | C12orf76 | 400073 | 2 | 2 | 16 | |
| TCGA | C12orf76 | 400073 | 22 | 10 | 64 |
Total number of gains: 60; Total number of losses: 29; Total Number of normals: 399.
Somatic mutations of C12orf76:
Generating mutation plots.
Highly correlated genes for C12orf76:
Showing top 20/478 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C12orf76 | U2SURP | 0.722039 | 3 | 0 | 3 |
| C12orf76 | FBRSL1 | 0.710629 | 3 | 0 | 3 |
| C12orf76 | P4HA1 | 0.694089 | 3 | 0 | 3 |
| C12orf76 | GNA13 | 0.678835 | 3 | 0 | 3 |
| C12orf76 | CDC42EP4 | 0.675817 | 3 | 0 | 3 |
| C12orf76 | UXS1 | 0.669901 | 3 | 0 | 3 |
| C12orf76 | DGUOK | 0.669494 | 4 | 0 | 4 |
| C12orf76 | ANKRD23 | 0.660025 | 3 | 0 | 3 |
| C12orf76 | TRAF5 | 0.655966 | 3 | 0 | 3 |
| C12orf76 | SNRPG | 0.652672 | 4 | 0 | 4 |
| C12orf76 | POLR3F | 0.651748 | 3 | 0 | 3 |
| C12orf76 | APMAP | 0.648759 | 5 | 0 | 5 |
| C12orf76 | DSCC1 | 0.642483 | 3 | 0 | 3 |
| C12orf76 | EIF2B5 | 0.642457 | 3 | 0 | 3 |
| C12orf76 | BOD1 | 0.641814 | 3 | 0 | 3 |
| C12orf76 | ATR | 0.636864 | 4 | 0 | 4 |
| C12orf76 | C11orf49 | 0.6364 | 4 | 0 | 3 |
| C12orf76 | KNSTRN | 0.635677 | 5 | 0 | 5 |
| C12orf76 | SOX4 | 0.63496 | 5 | 0 | 5 |
| C12orf76 | PELI2 | 0.632282 | 4 | 0 | 3 |
For details and further investigation, click here
