| Full name: IKAROS family zinc finger 5 | Alias Symbol: Pegasus|FLJ22973 | ||
| Type: protein-coding gene | Cytoband: 10q26.13 | ||
| Entrez ID: 64376 | HGNC ID: HGNC:14283 | Ensembl Gene: ENSG00000095574 | OMIM ID: 606238 |
| Drug and gene relationship at DGIdb | |||
Expression of IKZF5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IKZF5 | 64376 | 220086_at | -0.1570 | 0.5955 | |
| GSE20347 | IKZF5 | 64376 | 220086_at | 0.0496 | 0.5879 | |
| GSE23400 | IKZF5 | 64376 | 220086_at | -0.0566 | 0.1641 | |
| GSE26886 | IKZF5 | 64376 | 220086_at | -0.9953 | 0.0000 | |
| GSE29001 | IKZF5 | 64376 | 220086_at | -0.0673 | 0.6778 | |
| GSE38129 | IKZF5 | 64376 | 220086_at | 0.0484 | 0.7007 | |
| GSE45670 | IKZF5 | 64376 | 226680_at | -0.5846 | 0.0014 | |
| GSE53622 | IKZF5 | 64376 | 89195 | -0.2776 | 0.0001 | |
| GSE53624 | IKZF5 | 64376 | 89195 | -0.0714 | 0.3735 | |
| GSE63941 | IKZF5 | 64376 | 220086_at | 1.4588 | 0.0002 | |
| GSE77861 | IKZF5 | 64376 | 220086_at | -0.1445 | 0.5392 | |
| GSE97050 | IKZF5 | 64376 | A_33_P3421520 | 0.1109 | 0.5899 | |
| SRP007169 | IKZF5 | 64376 | RNAseq | -0.2869 | 0.5172 | |
| SRP008496 | IKZF5 | 64376 | RNAseq | -0.2076 | 0.4309 | |
| SRP064894 | IKZF5 | 64376 | RNAseq | -0.5713 | 0.0073 | |
| SRP133303 | IKZF5 | 64376 | RNAseq | -0.1013 | 0.4765 | |
| SRP159526 | IKZF5 | 64376 | RNAseq | -0.6025 | 0.0373 | |
| SRP193095 | IKZF5 | 64376 | RNAseq | -0.3729 | 0.0001 | |
| SRP219564 | IKZF5 | 64376 | RNAseq | -0.4567 | 0.2025 | |
| TCGA | IKZF5 | 64376 | RNAseq | -0.1903 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by IKZF5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IKZF5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IKZF5 | 64376 | 1 | 6 | 23 | |
| GSE20123 | IKZF5 | 64376 | 1 | 6 | 23 | |
| GSE43470 | IKZF5 | 64376 | 0 | 9 | 34 | |
| GSE46452 | IKZF5 | 64376 | 0 | 11 | 48 | |
| GSE47630 | IKZF5 | 64376 | 2 | 14 | 24 | |
| GSE54993 | IKZF5 | 64376 | 8 | 1 | 61 | |
| GSE54994 | IKZF5 | 64376 | 1 | 9 | 43 | |
| GSE60625 | IKZF5 | 64376 | 0 | 0 | 11 | |
| GSE74703 | IKZF5 | 64376 | 0 | 6 | 30 | |
| GSE74704 | IKZF5 | 64376 | 1 | 2 | 17 | |
| TCGA | IKZF5 | 64376 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 92; Total Number of normals: 378.
Somatic mutations of IKZF5:
Generating mutation plots.
Highly correlated genes for IKZF5:
Showing top 20/317 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IKZF5 | ATP6V1B2 | 0.795176 | 3 | 0 | 3 |
| IKZF5 | C16orf72 | 0.759471 | 3 | 0 | 3 |
| IKZF5 | ZNF740 | 0.753986 | 3 | 0 | 3 |
| IKZF5 | GNAI3 | 0.74646 | 3 | 0 | 3 |
| IKZF5 | ARPC2 | 0.742851 | 3 | 0 | 3 |
| IKZF5 | UFC1 | 0.737943 | 3 | 0 | 3 |
| IKZF5 | SLC44A3 | 0.713821 | 3 | 0 | 3 |
| IKZF5 | FRMD4B | 0.709958 | 4 | 0 | 3 |
| IKZF5 | MLKL | 0.709088 | 3 | 0 | 3 |
| IKZF5 | RBM20 | 0.703896 | 4 | 0 | 4 |
| IKZF5 | UBE2D2 | 0.699328 | 4 | 0 | 4 |
| IKZF5 | MRRF | 0.695573 | 4 | 0 | 4 |
| IKZF5 | COBLL1 | 0.680695 | 3 | 0 | 3 |
| IKZF5 | TRMT2B | 0.679958 | 3 | 0 | 3 |
| IKZF5 | CASP10 | 0.679668 | 3 | 0 | 3 |
| IKZF5 | RAD23B | 0.676571 | 4 | 0 | 3 |
| IKZF5 | STK19 | 0.674852 | 4 | 0 | 3 |
| IKZF5 | RBM8A | 0.673379 | 4 | 0 | 3 |
| IKZF5 | DHX35 | 0.67297 | 4 | 0 | 3 |
| IKZF5 | UBE2G1 | 0.672146 | 5 | 0 | 4 |
For details and further investigation, click here
