| Full name: chromosome 1 open reading frame 74 | Alias Symbol: FLJ25078|URLC4 | ||
| Type: protein-coding gene | Cytoband: 1q32.2 | ||
| Entrez ID: 148304 | HGNC ID: HGNC:26319 | Ensembl Gene: ENSG00000162757 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C1orf74:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1orf74 | 148304 | 229933_at | 0.3993 | 0.4518 | |
| GSE26886 | C1orf74 | 148304 | 229933_at | 0.4802 | 0.0349 | |
| GSE45670 | C1orf74 | 148304 | 231932_at | 0.5274 | 0.0901 | |
| GSE53622 | C1orf74 | 148304 | 43443 | 0.4902 | 0.0016 | |
| GSE53624 | C1orf74 | 148304 | 43443 | 0.4752 | 0.0000 | |
| GSE63941 | C1orf74 | 148304 | 229933_at | 0.7777 | 0.0204 | |
| GSE77861 | C1orf74 | 148304 | 229933_at | 0.1223 | 0.5237 | |
| GSE97050 | C1orf74 | 148304 | A_23_P12147 | 1.0618 | 0.3005 | |
| SRP007169 | C1orf74 | 148304 | RNAseq | -0.6420 | 0.2189 | |
| SRP064894 | C1orf74 | 148304 | RNAseq | 0.6500 | 0.0458 | |
| SRP133303 | C1orf74 | 148304 | RNAseq | 0.5394 | 0.1133 | |
| SRP159526 | C1orf74 | 148304 | RNAseq | 0.5356 | 0.3242 | |
| SRP193095 | C1orf74 | 148304 | RNAseq | 0.4583 | 0.0932 | |
| SRP219564 | C1orf74 | 148304 | RNAseq | 1.2418 | 0.1331 | |
| TCGA | C1orf74 | 148304 | RNAseq | 0.5752 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C1orf74 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1orf74:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1orf74 | 148304 | 11 | 0 | 19 | |
| GSE20123 | C1orf74 | 148304 | 10 | 0 | 20 | |
| GSE43470 | C1orf74 | 148304 | 7 | 0 | 36 | |
| GSE46452 | C1orf74 | 148304 | 3 | 1 | 55 | |
| GSE47630 | C1orf74 | 148304 | 15 | 0 | 25 | |
| GSE54993 | C1orf74 | 148304 | 0 | 6 | 64 | |
| GSE54994 | C1orf74 | 148304 | 14 | 0 | 39 | |
| GSE60625 | C1orf74 | 148304 | 0 | 0 | 11 | |
| GSE74703 | C1orf74 | 148304 | 7 | 0 | 29 | |
| GSE74704 | C1orf74 | 148304 | 4 | 0 | 16 | |
| TCGA | C1orf74 | 148304 | 44 | 3 | 49 |
Total number of gains: 115; Total number of losses: 10; Total Number of normals: 363.
Somatic mutations of C1orf74:
Generating mutation plots.
Highly correlated genes for C1orf74:
Showing top 20/332 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1orf74 | WIPI2 | 0.706603 | 3 | 0 | 3 |
| C1orf74 | TOP1 | 0.685691 | 3 | 0 | 3 |
| C1orf74 | MAPK8 | 0.681795 | 3 | 0 | 3 |
| C1orf74 | PRKCZ | 0.681149 | 3 | 0 | 3 |
| C1orf74 | NCKIPSD | 0.675438 | 3 | 0 | 3 |
| C1orf74 | IL32 | 0.674593 | 3 | 0 | 3 |
| C1orf74 | KPNA2 | 0.67323 | 3 | 0 | 3 |
| C1orf74 | GTSE1 | 0.667845 | 4 | 0 | 4 |
| C1orf74 | UTP18 | 0.662609 | 3 | 0 | 3 |
| C1orf74 | LSR | 0.662044 | 3 | 0 | 3 |
| C1orf74 | EFHD2 | 0.65937 | 4 | 0 | 4 |
| C1orf74 | RSRC1 | 0.653099 | 3 | 0 | 3 |
| C1orf74 | NUP43 | 0.651915 | 3 | 0 | 3 |
| C1orf74 | GTSF1 | 0.65018 | 3 | 0 | 3 |
| C1orf74 | LMNB2 | 0.647212 | 3 | 0 | 3 |
| C1orf74 | GNL2 | 0.642718 | 6 | 0 | 5 |
| C1orf74 | NAGPA | 0.642207 | 3 | 0 | 3 |
| C1orf74 | PLCG1 | 0.641665 | 3 | 0 | 3 |
| C1orf74 | TBX15 | 0.639648 | 4 | 0 | 3 |
| C1orf74 | FANCD2 | 0.633443 | 4 | 0 | 3 |
For details and further investigation, click here
