| Full name: zinc finger NFX1-type containing 1 | Alias Symbol: KIAA1404|FLJ11277 | ||
| Type: protein-coding gene | Cytoband: 20q13.13 | ||
| Entrez ID: 57169 | HGNC ID: HGNC:29271 | Ensembl Gene: ENSG00000124201 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZNFX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNFX1 | 57169 | 225076_s_at | 0.7386 | 0.0402 | |
| GSE26886 | ZNFX1 | 57169 | 225076_s_at | 0.6197 | 0.0157 | |
| GSE45670 | ZNFX1 | 57169 | 225076_s_at | 0.6944 | 0.0020 | |
| GSE53622 | ZNFX1 | 57169 | 57827 | 0.8283 | 0.0000 | |
| GSE53624 | ZNFX1 | 57169 | 57827 | 0.8799 | 0.0000 | |
| GSE63941 | ZNFX1 | 57169 | 225076_s_at | -0.6172 | 0.4011 | |
| GSE77861 | ZNFX1 | 57169 | 225076_s_at | 0.3344 | 0.0701 | |
| GSE97050 | ZNFX1 | 57169 | A_24_P23034 | 0.6952 | 0.0781 | |
| SRP007169 | ZNFX1 | 57169 | RNAseq | 1.3715 | 0.0015 | |
| SRP008496 | ZNFX1 | 57169 | RNAseq | 1.0774 | 0.0000 | |
| SRP064894 | ZNFX1 | 57169 | RNAseq | 0.7658 | 0.0001 | |
| SRP133303 | ZNFX1 | 57169 | RNAseq | 0.7583 | 0.0000 | |
| SRP159526 | ZNFX1 | 57169 | RNAseq | 0.0104 | 0.9710 | |
| SRP193095 | ZNFX1 | 57169 | RNAseq | 0.7293 | 0.0000 | |
| SRP219564 | ZNFX1 | 57169 | RNAseq | 0.5888 | 0.1817 | |
| TCGA | ZNFX1 | 57169 | RNAseq | 0.0015 | 0.9777 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ZNFX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNFX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNFX1 | 57169 | 16 | 2 | 12 | |
| GSE20123 | ZNFX1 | 57169 | 16 | 2 | 12 | |
| GSE43470 | ZNFX1 | 57169 | 12 | 0 | 31 | |
| GSE46452 | ZNFX1 | 57169 | 29 | 0 | 30 | |
| GSE47630 | ZNFX1 | 57169 | 24 | 1 | 15 | |
| GSE54993 | ZNFX1 | 57169 | 0 | 17 | 53 | |
| GSE54994 | ZNFX1 | 57169 | 27 | 0 | 26 | |
| GSE60625 | ZNFX1 | 57169 | 0 | 0 | 11 | |
| GSE74703 | ZNFX1 | 57169 | 10 | 0 | 26 | |
| GSE74704 | ZNFX1 | 57169 | 12 | 0 | 8 | |
| TCGA | ZNFX1 | 57169 | 46 | 3 | 47 |
Total number of gains: 192; Total number of losses: 25; Total Number of normals: 271.
Somatic mutations of ZNFX1:
Generating mutation plots.
Highly correlated genes for ZNFX1:
Showing top 20/1242 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNFX1 | CD80 | 0.776096 | 3 | 0 | 3 |
| ZNFX1 | LRRC8C | 0.768571 | 3 | 0 | 3 |
| ZNFX1 | NCOR2 | 0.768024 | 3 | 0 | 3 |
| ZNFX1 | GBP1 | 0.733068 | 8 | 0 | 8 |
| ZNFX1 | IFITM3 | 0.727044 | 9 | 0 | 9 |
| ZNFX1 | EIF2AK2 | 0.726813 | 7 | 0 | 7 |
| ZNFX1 | NOTCH1 | 0.725969 | 3 | 0 | 3 |
| ZNFX1 | HELZ2 | 0.718972 | 6 | 0 | 6 |
| ZNFX1 | DDX60 | 0.716481 | 9 | 0 | 8 |
| ZNFX1 | IFI6 | 0.714102 | 9 | 0 | 9 |
| ZNFX1 | USP41 | 0.712428 | 3 | 0 | 3 |
| ZNFX1 | PARP14 | 0.711576 | 9 | 0 | 8 |
| ZNFX1 | CASK | 0.709603 | 3 | 0 | 3 |
| ZNFX1 | PLOD1 | 0.709579 | 6 | 0 | 6 |
| ZNFX1 | FCGR3A | 0.706809 | 3 | 0 | 3 |
| ZNFX1 | PARP12 | 0.706367 | 9 | 0 | 9 |
| ZNFX1 | DDX60L | 0.705877 | 7 | 0 | 7 |
| ZNFX1 | IFI35 | 0.699793 | 9 | 0 | 8 |
| ZNFX1 | DTX3L | 0.696598 | 9 | 0 | 7 |
| ZNFX1 | STAT2 | 0.696104 | 6 | 0 | 6 |
For details and further investigation, click here
