| Full name: chromosome 1 open reading frame 109 | Alias Symbol: FLJ20508 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 54955 | HGNC ID: HGNC:26039 | Ensembl Gene: ENSG00000116922 | OMIM ID: 614799 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of C1orf109:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1orf109 | 54955 | 218712_at | 0.7177 | 0.1225 | |
| GSE20347 | C1orf109 | 54955 | 218712_at | 0.5986 | 0.0010 | |
| GSE23400 | C1orf109 | 54955 | 218712_at | 0.3613 | 0.0000 | |
| GSE26886 | C1orf109 | 54955 | 218712_at | 0.6527 | 0.0198 | |
| GSE29001 | C1orf109 | 54955 | 218712_at | 0.6332 | 0.0251 | |
| GSE38129 | C1orf109 | 54955 | 218712_at | 0.5638 | 0.0000 | |
| GSE45670 | C1orf109 | 54955 | 218712_at | 0.2283 | 0.1244 | |
| GSE53622 | C1orf109 | 54955 | 47893 | 0.6527 | 0.0000 | |
| GSE53624 | C1orf109 | 54955 | 47893 | 0.6560 | 0.0000 | |
| GSE63941 | C1orf109 | 54955 | 218712_at | 0.0442 | 0.9236 | |
| GSE77861 | C1orf109 | 54955 | 218712_at | 0.0804 | 0.7253 | |
| GSE97050 | C1orf109 | 54955 | A_23_P45970 | 0.3295 | 0.2485 | |
| SRP007169 | C1orf109 | 54955 | RNAseq | 1.1599 | 0.0328 | |
| SRP008496 | C1orf109 | 54955 | RNAseq | 0.7001 | 0.0482 | |
| SRP064894 | C1orf109 | 54955 | RNAseq | 0.3190 | 0.1863 | |
| SRP133303 | C1orf109 | 54955 | RNAseq | 0.6329 | 0.0000 | |
| SRP159526 | C1orf109 | 54955 | RNAseq | 0.4730 | 0.0851 | |
| SRP193095 | C1orf109 | 54955 | RNAseq | 0.3484 | 0.0007 | |
| SRP219564 | C1orf109 | 54955 | RNAseq | 0.5585 | 0.1974 | |
| TCGA | C1orf109 | 54955 | RNAseq | 0.1374 | 0.0262 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by C1orf109 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1orf109:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1orf109 | 54955 | 2 | 4 | 24 | |
| GSE20123 | C1orf109 | 54955 | 2 | 3 | 25 | |
| GSE43470 | C1orf109 | 54955 | 7 | 3 | 33 | |
| GSE46452 | C1orf109 | 54955 | 4 | 1 | 54 | |
| GSE47630 | C1orf109 | 54955 | 8 | 3 | 29 | |
| GSE54993 | C1orf109 | 54955 | 1 | 1 | 68 | |
| GSE54994 | C1orf109 | 54955 | 12 | 2 | 39 | |
| GSE60625 | C1orf109 | 54955 | 0 | 0 | 11 | |
| GSE74703 | C1orf109 | 54955 | 6 | 2 | 28 | |
| GSE74704 | C1orf109 | 54955 | 1 | 0 | 19 | |
| TCGA | C1orf109 | 54955 | 12 | 16 | 68 |
Total number of gains: 55; Total number of losses: 35; Total Number of normals: 398.
Somatic mutations of C1orf109:
Generating mutation plots.
Highly correlated genes for C1orf109:
Showing top 20/757 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1orf109 | COL27A1 | 0.715646 | 3 | 0 | 3 |
| C1orf109 | MIB2 | 0.708937 | 3 | 0 | 3 |
| C1orf109 | CDCA8 | 0.706517 | 9 | 0 | 9 |
| C1orf109 | ZFP69 | 0.687872 | 5 | 0 | 4 |
| C1orf109 | HNRNPR | 0.683079 | 9 | 0 | 9 |
| C1orf109 | CTPS1 | 0.677846 | 10 | 0 | 10 |
| C1orf109 | NDC1 | 0.672328 | 10 | 0 | 9 |
| C1orf109 | CDC20 | 0.667087 | 9 | 0 | 9 |
| C1orf109 | YBX1 | 0.666036 | 9 | 0 | 8 |
| C1orf109 | KDM1A | 0.652528 | 8 | 0 | 7 |
| C1orf109 | COA7 | 0.651799 | 9 | 0 | 6 |
| C1orf109 | ERCC6L | 0.651395 | 7 | 0 | 6 |
| C1orf109 | ARHGAP21 | 0.649219 | 4 | 0 | 3 |
| C1orf109 | G2E3 | 0.647968 | 4 | 0 | 4 |
| C1orf109 | F11R | 0.64787 | 3 | 0 | 3 |
| C1orf109 | TXNDC12 | 0.643698 | 7 | 0 | 6 |
| C1orf109 | MCM6 | 0.643054 | 8 | 0 | 7 |
| C1orf109 | EMC1 | 0.64261 | 8 | 0 | 6 |
| C1orf109 | HOXC13 | 0.642033 | 4 | 0 | 3 |
| C1orf109 | ORC1 | 0.641576 | 8 | 0 | 5 |
For details and further investigation, click here
