Full name: ERCC excision repair 6 like, spindle assembly checkpoint helicase	Alias Symbol: FLJ20105|PICH|RAD26L
Type: protein-coding gene	Cytoband: Xq13.1
Entrez ID: 54821	HGNC ID: HGNC:20794	Ensembl Gene: ENSG00000186871	OMIM ID: 300687
Drug and gene relationship at DGIdb
Screen Evidence: Knocking out of this gene by CRIPR/Cas9 screen found 45/325 cell lines had fitness change in Project Score. Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

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Expression of ERCC6L:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	ERCC6L	54821	219650_at	0.8730	0.0339	Show
GSE20347	ERCC6L	54821	219650_at	0.6318	0.0000	Show
GSE23400	ERCC6L	54821	219650_at	0.2924	0.0000	Show
GSE26886	ERCC6L	54821	219650_at	0.1711	0.4587	Show
GSE29001	ERCC6L	54821	219650_at	0.8420	0.0017	Show
GSE38129	ERCC6L	54821	219650_at	0.9377	0.0000	Show
GSE45670	ERCC6L	54821	219650_at	0.8098	0.0000	Show
GSE53622	ERCC6L	54821	91293	1.5149	0.0000	Show
GSE53624	ERCC6L	54821	91293	1.6702	0.0000	Show
GSE63941	ERCC6L	54821	219650_at	1.6025	0.0129	Show
GSE77861	ERCC6L	54821	219650_at	0.2503	0.1504	Show
GSE97050	ERCC6L	54821	A_23_P96325	0.1410	0.8758	Show
SRP007169	ERCC6L	54821	RNAseq	1.7577	0.0019	Show
SRP008496	ERCC6L	54821	RNAseq	1.2397	0.0101	Show
SRP064894	ERCC6L	54821	RNAseq	1.4268	0.0000	Show
SRP133303	ERCC6L	54821	RNAseq	1.0751	0.0000	Show
SRP159526	ERCC6L	54821	RNAseq	0.7972	0.0103	Show
SRP193095	ERCC6L	54821	RNAseq	0.7466	0.0000	Show
SRP219564	ERCC6L	54821	RNAseq	1.0020	0.1071	Show
TCGA	ERCC6L	54821	RNAseq	1.0942	0.0000	Show

Upregulated datasets: 8; Downregulated datasets: 0.  Download Data

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Survival by ERCC6L expression:

 

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Copy number change of ERCC6L:

 

No record found for this gene.

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Somatic mutations of ERCC6L:

 

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Highly correlated genes for ERCC6L:

 

Showing top 20/1572 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
ERCC6L	CDC6	0.791632	9	0	9
ERCC6L	DEPDC1B	0.78799	6	0	6
ERCC6L	STIL	0.786208	10	0	10
ERCC6L	CDC20	0.781765	10	0	10
ERCC6L	KIF4A	0.781364	11	0	10
ERCC6L	CDCA3	0.780319	11	0	10
ERCC6L	C1orf112	0.776448	9	0	8
ERCC6L	GINS1	0.774763	10	0	10
ERCC6L	EXO1	0.773308	11	0	11
ERCC6L	MCM6	0.771985	10	0	10
ERCC6L	RFC4	0.767624	10	0	10
ERCC6L	CEP55	0.766572	11	0	10
ERCC6L	GMNN	0.76495	11	0	10
ERCC6L	KIF18A	0.763188	11	0	10
ERCC6L	BUB1	0.762897	9	0	8
ERCC6L	MCM10	0.760572	10	0	10
ERCC6L	TOP2A	0.758621	10	0	10
ERCC6L	MELK	0.756628	11	0	10
ERCC6L	FBXO5	0.756586	10	0	10
ERCC6L	RAD51	0.756132	11	0	10

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