| Full name: DNA cross-link repair 1B | Alias Symbol: SNM1B|FLJ12810|FLJ13998|APOLLO | ||
| Type: protein-coding gene | Cytoband: 1p13.2 | ||
| Entrez ID: 64858 | HGNC ID: HGNC:17641 | Ensembl Gene: ENSG00000118655 | OMIM ID: 609683 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of DCLRE1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCLRE1B | 64858 | 222889_at | 0.5858 | 0.4476 | |
| GSE20347 | DCLRE1B | 64858 | 219490_s_at | 0.2040 | 0.0534 | |
| GSE23400 | DCLRE1B | 64858 | 219490_s_at | 0.0180 | 0.7059 | |
| GSE26886 | DCLRE1B | 64858 | 222889_at | 0.0987 | 0.8037 | |
| GSE29001 | DCLRE1B | 64858 | 219490_s_at | 0.1412 | 0.5264 | |
| GSE38129 | DCLRE1B | 64858 | 219490_s_at | 0.2398 | 0.0067 | |
| GSE45670 | DCLRE1B | 64858 | 222889_at | 0.2357 | 0.4158 | |
| GSE53622 | DCLRE1B | 64858 | 98070 | 0.3132 | 0.0076 | |
| GSE53624 | DCLRE1B | 64858 | 98070 | 0.6172 | 0.0000 | |
| GSE63941 | DCLRE1B | 64858 | 222889_at | 0.1219 | 0.8662 | |
| GSE77861 | DCLRE1B | 64858 | 219490_s_at | -0.0231 | 0.8651 | |
| GSE97050 | DCLRE1B | 64858 | A_24_P54131 | 0.2476 | 0.3332 | |
| SRP007169 | DCLRE1B | 64858 | RNAseq | 0.3217 | 0.5993 | |
| SRP008496 | DCLRE1B | 64858 | RNAseq | 0.0057 | 0.9889 | |
| SRP064894 | DCLRE1B | 64858 | RNAseq | 0.2852 | 0.2244 | |
| SRP133303 | DCLRE1B | 64858 | RNAseq | 0.6225 | 0.0007 | |
| SRP159526 | DCLRE1B | 64858 | RNAseq | 0.0936 | 0.7401 | |
| SRP193095 | DCLRE1B | 64858 | RNAseq | 0.4097 | 0.0113 | |
| SRP219564 | DCLRE1B | 64858 | RNAseq | 0.5794 | 0.2944 | |
| TCGA | DCLRE1B | 64858 | RNAseq | 0.4799 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DCLRE1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCLRE1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCLRE1B | 64858 | 0 | 9 | 21 | |
| GSE20123 | DCLRE1B | 64858 | 0 | 9 | 21 | |
| GSE43470 | DCLRE1B | 64858 | 0 | 8 | 35 | |
| GSE46452 | DCLRE1B | 64858 | 2 | 1 | 56 | |
| GSE47630 | DCLRE1B | 64858 | 9 | 5 | 26 | |
| GSE54993 | DCLRE1B | 64858 | 0 | 1 | 69 | |
| GSE54994 | DCLRE1B | 64858 | 7 | 3 | 43 | |
| GSE60625 | DCLRE1B | 64858 | 0 | 0 | 11 | |
| GSE74703 | DCLRE1B | 64858 | 0 | 7 | 29 | |
| GSE74704 | DCLRE1B | 64858 | 0 | 5 | 15 | |
| TCGA | DCLRE1B | 64858 | 11 | 30 | 55 |
Total number of gains: 29; Total number of losses: 78; Total Number of normals: 381.
Somatic mutations of DCLRE1B:
Generating mutation plots.
Highly correlated genes for DCLRE1B:
Showing top 20/304 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCLRE1B | SNRPB2 | 0.736324 | 3 | 0 | 3 |
| DCLRE1B | TRIM59 | 0.730648 | 3 | 0 | 3 |
| DCLRE1B | C21orf91 | 0.713998 | 3 | 0 | 3 |
| DCLRE1B | ZFPL1 | 0.703778 | 3 | 0 | 3 |
| DCLRE1B | ANKRD13C | 0.700395 | 3 | 0 | 3 |
| DCLRE1B | TOMM22 | 0.695523 | 3 | 0 | 3 |
| DCLRE1B | ZNF227 | 0.694454 | 3 | 0 | 3 |
| DCLRE1B | TRMT12 | 0.689947 | 4 | 0 | 4 |
| DCLRE1B | IL1RAP | 0.688699 | 3 | 0 | 3 |
| DCLRE1B | ANKRD50 | 0.680153 | 3 | 0 | 3 |
| DCLRE1B | NIF3L1 | 0.671475 | 3 | 0 | 3 |
| DCLRE1B | CINP | 0.670166 | 3 | 0 | 3 |
| DCLRE1B | UBE3C | 0.66625 | 4 | 0 | 3 |
| DCLRE1B | HRH1 | 0.660821 | 4 | 0 | 3 |
| DCLRE1B | C18orf54 | 0.660619 | 3 | 0 | 3 |
| DCLRE1B | WDR89 | 0.65693 | 4 | 0 | 3 |
| DCLRE1B | USP13 | 0.656062 | 3 | 0 | 3 |
| DCLRE1B | ZNF22 | 0.654889 | 3 | 0 | 3 |
| DCLRE1B | ZBTB34 | 0.652395 | 4 | 0 | 4 |
| DCLRE1B | PIGM | 0.651914 | 3 | 0 | 3 |
For details and further investigation, click here
