| Full name: C2 calcium dependent domain containing 4C | Alias Symbol: NLF3 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 126567 | HGNC ID: HGNC:29417 | Ensembl Gene: ENSG00000183186 | OMIM ID: 610336 |
| Drug and gene relationship at DGIdb | |||
Expression of C2CD4C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C2CD4C | 126567 | 230819_at | -0.0071 | 0.9864 | |
| GSE26886 | C2CD4C | 126567 | 230819_at | 0.3108 | 0.0658 | |
| GSE45670 | C2CD4C | 126567 | 230819_at | 0.0867 | 0.3196 | |
| GSE53622 | C2CD4C | 126567 | 10637 | 0.3389 | 0.0004 | |
| GSE53624 | C2CD4C | 126567 | 10637 | 0.5757 | 0.0000 | |
| GSE63941 | C2CD4C | 126567 | 230819_at | 0.3032 | 0.1357 | |
| GSE77861 | C2CD4C | 126567 | 230819_at | -0.0564 | 0.6472 | |
| GSE97050 | C2CD4C | 126567 | A_33_P3215412 | 0.1732 | 0.4639 | |
| SRP133303 | C2CD4C | 126567 | RNAseq | 1.6195 | 0.0001 | |
| SRP159526 | C2CD4C | 126567 | RNAseq | 1.2466 | 0.0533 | |
| SRP219564 | C2CD4C | 126567 | RNAseq | 0.7602 | 0.3381 | |
| TCGA | C2CD4C | 126567 | RNAseq | 0.2853 | 0.3639 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by C2CD4C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C2CD4C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C2CD4C | 126567 | 8 | 6 | 16 | |
| GSE20123 | C2CD4C | 126567 | 8 | 5 | 17 | |
| GSE43470 | C2CD4C | 126567 | 1 | 10 | 32 | |
| GSE46452 | C2CD4C | 126567 | 47 | 1 | 11 | |
| GSE47630 | C2CD4C | 126567 | 5 | 7 | 28 | |
| GSE54993 | C2CD4C | 126567 | 13 | 4 | 53 | |
| GSE54994 | C2CD4C | 126567 | 8 | 15 | 30 | |
| GSE60625 | C2CD4C | 126567 | 9 | 0 | 2 | |
| GSE74703 | C2CD4C | 126567 | 1 | 7 | 28 | |
| GSE74704 | C2CD4C | 126567 | 7 | 3 | 10 | |
| TCGA | C2CD4C | 126567 | 8 | 25 | 63 |
Total number of gains: 115; Total number of losses: 83; Total Number of normals: 290.
Somatic mutations of C2CD4C:
Generating mutation plots.
Highly correlated genes for C2CD4C:
Showing top 20/151 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C2CD4C | FOXA2 | 0.669638 | 3 | 0 | 3 |
| C2CD4C | CLDN14 | 0.669605 | 4 | 0 | 4 |
| C2CD4C | OR3A3 | 0.667919 | 3 | 0 | 3 |
| C2CD4C | CCL27 | 0.655038 | 3 | 0 | 3 |
| C2CD4C | CRYAA | 0.648642 | 4 | 0 | 4 |
| C2CD4C | GBX2 | 0.648288 | 3 | 0 | 3 |
| C2CD4C | TSPAN32 | 0.641417 | 5 | 0 | 4 |
| C2CD4C | HMCN2 | 0.6392 | 3 | 0 | 3 |
| C2CD4C | CHRNA4 | 0.638773 | 3 | 0 | 3 |
| C2CD4C | CRYGN | 0.638327 | 4 | 0 | 3 |
| C2CD4C | CACNA1H | 0.634769 | 3 | 0 | 3 |
| C2CD4C | CHGA | 0.631856 | 3 | 0 | 3 |
| C2CD4C | KRT20 | 0.631783 | 3 | 0 | 3 |
| C2CD4C | NXNL1 | 0.629907 | 3 | 0 | 3 |
| C2CD4C | BPIFB4 | 0.627128 | 3 | 0 | 3 |
| C2CD4C | KCNN2 | 0.621497 | 3 | 0 | 3 |
| C2CD4C | SLC5A11 | 0.620283 | 4 | 0 | 4 |
| C2CD4C | TBXA2R | 0.61569 | 3 | 0 | 3 |
| C2CD4C | MOGAT3 | 0.613968 | 3 | 0 | 3 |
| C2CD4C | CACNA1A | 0.613638 | 5 | 0 | 4 |
For details and further investigation, click here
