| Full name: calbindin 2 | Alias Symbol: CAL2 | ||
| Type: protein-coding gene | Cytoband: 16q22.2 | ||
| Entrez ID: 794 | HGNC ID: HGNC:1435 | Ensembl Gene: ENSG00000172137 | OMIM ID: 114051 |
| Drug and gene relationship at DGIdb | |||
Expression of CALB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CALB2 | 794 | 205428_s_at | -0.7995 | 0.5548 | |
| GSE20347 | CALB2 | 794 | 205428_s_at | -0.9624 | 0.0005 | |
| GSE23400 | CALB2 | 794 | 205428_s_at | -0.5343 | 0.0000 | |
| GSE26886 | CALB2 | 794 | 205428_s_at | -0.5928 | 0.1328 | |
| GSE29001 | CALB2 | 794 | 205428_s_at | -0.6338 | 0.1137 | |
| GSE38129 | CALB2 | 794 | 205428_s_at | -0.7193 | 0.0074 | |
| GSE45670 | CALB2 | 794 | 205428_s_at | -0.4392 | 0.1237 | |
| GSE53622 | CALB2 | 794 | 68271 | -1.0805 | 0.0008 | |
| GSE53624 | CALB2 | 794 | 79025 | -1.8738 | 0.0000 | |
| GSE63941 | CALB2 | 794 | 205428_s_at | 0.8966 | 0.4156 | |
| GSE77861 | CALB2 | 794 | 205428_s_at | -0.3550 | 0.4869 | |
| GSE97050 | CALB2 | 794 | A_23_P21092 | 0.5322 | 0.1413 | |
| SRP007169 | CALB2 | 794 | RNAseq | -3.9548 | 0.0000 | |
| SRP008496 | CALB2 | 794 | RNAseq | -2.5421 | 0.0000 | |
| SRP064894 | CALB2 | 794 | RNAseq | -2.4835 | 0.0000 | |
| SRP133303 | CALB2 | 794 | RNAseq | -1.5169 | 0.0029 | |
| SRP219564 | CALB2 | 794 | RNAseq | -0.9987 | 0.3475 | |
| TCGA | CALB2 | 794 | RNAseq | 0.8086 | 0.0594 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by CALB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CALB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CALB2 | 794 | 4 | 0 | 26 | |
| GSE20123 | CALB2 | 794 | 4 | 0 | 26 | |
| GSE43470 | CALB2 | 794 | 2 | 8 | 33 | |
| GSE46452 | CALB2 | 794 | 38 | 2 | 19 | |
| GSE47630 | CALB2 | 794 | 11 | 8 | 21 | |
| GSE54993 | CALB2 | 794 | 2 | 4 | 64 | |
| GSE54994 | CALB2 | 794 | 8 | 10 | 35 | |
| GSE60625 | CALB2 | 794 | 4 | 0 | 7 | |
| GSE74703 | CALB2 | 794 | 2 | 5 | 29 | |
| GSE74704 | CALB2 | 794 | 2 | 0 | 18 | |
| TCGA | CALB2 | 794 | 28 | 12 | 56 |
Total number of gains: 105; Total number of losses: 49; Total Number of normals: 334.
Somatic mutations of CALB2:
Generating mutation plots.
Highly correlated genes for CALB2:
Showing top 20/533 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CALB2 | PGLYRP3 | 0.669093 | 4 | 0 | 4 |
| CALB2 | KRT80 | 0.667581 | 5 | 0 | 5 |
| CALB2 | DMKN | 0.65358 | 5 | 0 | 5 |
| CALB2 | SPRR2B | 0.647394 | 3 | 0 | 3 |
| CALB2 | TREX2 | 0.645048 | 3 | 0 | 3 |
| CALB2 | TINCR | 0.642156 | 3 | 0 | 3 |
| CALB2 | CST6 | 0.641986 | 10 | 0 | 9 |
| CALB2 | TOM1 | 0.641984 | 11 | 0 | 10 |
| CALB2 | BAIAP2 | 0.639624 | 9 | 0 | 9 |
| CALB2 | CYP4F22 | 0.638211 | 4 | 0 | 3 |
| CALB2 | CDA | 0.637556 | 11 | 0 | 10 |
| CALB2 | NIPAL1 | 0.635037 | 3 | 0 | 3 |
| CALB2 | ELOVL1 | 0.63224 | 3 | 0 | 3 |
| CALB2 | ARHGAP5-AS1 | 0.628278 | 4 | 0 | 4 |
| CALB2 | RDH12 | 0.62783 | 7 | 0 | 6 |
| CALB2 | NUAK2 | 0.627244 | 3 | 0 | 3 |
| CALB2 | FBXL16 | 0.626504 | 7 | 0 | 6 |
| CALB2 | RABEP2 | 0.620132 | 3 | 0 | 3 |
| CALB2 | SPRR2D | 0.619152 | 3 | 0 | 3 |
| CALB2 | FAM83G | 0.617661 | 5 | 0 | 4 |
For details and further investigation, click here
