| Full name: SPRY domain containing 3 | Alias Symbol: FLJ14800 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 84926 | HGNC ID: HGNC:25920 | Ensembl Gene: ENSG00000167778 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SPRYD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPRYD3 | 84926 | 225134_at | -0.3574 | 0.2687 | |
| GSE26886 | SPRYD3 | 84926 | 225134_at | -0.0746 | 0.6882 | |
| GSE45670 | SPRYD3 | 84926 | 225134_at | -0.0501 | 0.6492 | |
| GSE53622 | SPRYD3 | 84926 | 41634 | -0.2949 | 0.0000 | |
| GSE53624 | SPRYD3 | 84926 | 41634 | -0.0565 | 0.2806 | |
| GSE63941 | SPRYD3 | 84926 | 225134_at | 0.0774 | 0.8123 | |
| GSE77861 | SPRYD3 | 84926 | 225134_at | 0.0305 | 0.8666 | |
| GSE97050 | SPRYD3 | 84926 | A_23_P65129 | -0.4277 | 0.2682 | |
| SRP007169 | SPRYD3 | 84926 | RNAseq | -0.8899 | 0.0172 | |
| SRP008496 | SPRYD3 | 84926 | RNAseq | -0.6574 | 0.0051 | |
| SRP064894 | SPRYD3 | 84926 | RNAseq | -0.0723 | 0.6962 | |
| SRP133303 | SPRYD3 | 84926 | RNAseq | -0.0208 | 0.9082 | |
| SRP159526 | SPRYD3 | 84926 | RNAseq | -0.4228 | 0.1138 | |
| SRP193095 | SPRYD3 | 84926 | RNAseq | -0.0737 | 0.4737 | |
| SRP219564 | SPRYD3 | 84926 | RNAseq | -0.1081 | 0.8577 | |
| TCGA | SPRYD3 | 84926 | RNAseq | -0.2641 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPRYD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPRYD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPRYD3 | 84926 | 8 | 1 | 21 | |
| GSE20123 | SPRYD3 | 84926 | 8 | 1 | 21 | |
| GSE43470 | SPRYD3 | 84926 | 3 | 0 | 40 | |
| GSE46452 | SPRYD3 | 84926 | 7 | 1 | 51 | |
| GSE47630 | SPRYD3 | 84926 | 10 | 2 | 28 | |
| GSE54993 | SPRYD3 | 84926 | 0 | 5 | 65 | |
| GSE54994 | SPRYD3 | 84926 | 4 | 1 | 48 | |
| GSE60625 | SPRYD3 | 84926 | 0 | 0 | 11 | |
| GSE74703 | SPRYD3 | 84926 | 3 | 0 | 33 | |
| GSE74704 | SPRYD3 | 84926 | 5 | 1 | 14 | |
| TCGA | SPRYD3 | 84926 | 13 | 11 | 72 |
Total number of gains: 61; Total number of losses: 23; Total Number of normals: 404.
Somatic mutations of SPRYD3:
Generating mutation plots.
Highly correlated genes for SPRYD3:
Showing top 20/249 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPRYD3 | PTH1R | 0.787977 | 3 | 0 | 3 |
| SPRYD3 | PNKD | 0.773383 | 3 | 0 | 3 |
| SPRYD3 | CUEDC1 | 0.758422 | 3 | 0 | 3 |
| SPRYD3 | RYR3 | 0.750672 | 3 | 0 | 3 |
| SPRYD3 | ITGA7 | 0.741764 | 3 | 0 | 3 |
| SPRYD3 | RGN | 0.740088 | 3 | 0 | 3 |
| SPRYD3 | LRFN5 | 0.736847 | 3 | 0 | 3 |
| SPRYD3 | NME5 | 0.733272 | 3 | 0 | 3 |
| SPRYD3 | PRKG2 | 0.724724 | 3 | 0 | 3 |
| SPRYD3 | PDZRN4 | 0.721353 | 3 | 0 | 3 |
| SPRYD3 | GAB1 | 0.718159 | 3 | 0 | 3 |
| SPRYD3 | PYGM | 0.712683 | 3 | 0 | 3 |
| SPRYD3 | KCND3 | 0.709833 | 4 | 0 | 4 |
| SPRYD3 | CCDC69 | 0.708236 | 3 | 0 | 3 |
| SPRYD3 | ADRB3 | 0.703824 | 3 | 0 | 3 |
| SPRYD3 | CDH19 | 0.70156 | 3 | 0 | 3 |
| SPRYD3 | PPP1R14A | 0.701328 | 3 | 0 | 3 |
| SPRYD3 | ITGA9 | 0.699384 | 3 | 0 | 3 |
| SPRYD3 | CKB | 0.698598 | 3 | 0 | 3 |
| SPRYD3 | CALM1 | 0.698031 | 3 | 0 | 3 |
For details and further investigation, click here
