| Full name: calnexin | Alias Symbol: CNX|IP90|P90 | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 821 | HGNC ID: HGNC:1473 | Ensembl Gene: ENSG00000127022 | OMIM ID: 114217 |
| Drug and gene relationship at DGIdb | |||
CANX involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05166 | HTLV-I infection |
Expression of CANX:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CANX | 821 | 200068_s_at | 0.2506 | 0.1854 | |
| GSE20347 | CANX | 821 | 200068_s_at | 0.0913 | 0.4696 | |
| GSE23400 | CANX | 821 | 200068_s_at | 0.2460 | 0.0000 | |
| GSE26886 | CANX | 821 | 200068_s_at | 0.0483 | 0.6564 | |
| GSE29001 | CANX | 821 | 200068_s_at | 0.0340 | 0.8640 | |
| GSE38129 | CANX | 821 | 200068_s_at | 0.1802 | 0.0844 | |
| GSE45670 | CANX | 821 | 200068_s_at | 0.1094 | 0.4697 | |
| GSE53622 | CANX | 821 | 22307 | 1.0622 | 0.0000 | |
| GSE53624 | CANX | 821 | 22307 | 0.7240 | 0.0000 | |
| GSE63941 | CANX | 821 | 200068_s_at | -0.2547 | 0.5191 | |
| GSE77861 | CANX | 821 | 200068_s_at | 0.0928 | 0.5468 | |
| GSE97050 | CANX | 821 | A_33_P3325131 | 0.9845 | 0.0555 | |
| SRP007169 | CANX | 821 | RNAseq | 0.5093 | 0.2244 | |
| SRP008496 | CANX | 821 | RNAseq | 0.4674 | 0.0413 | |
| SRP064894 | CANX | 821 | RNAseq | 0.2770 | 0.0703 | |
| SRP133303 | CANX | 821 | RNAseq | 0.5413 | 0.0014 | |
| SRP159526 | CANX | 821 | RNAseq | 0.4095 | 0.2503 | |
| SRP193095 | CANX | 821 | RNAseq | 0.0286 | 0.8245 | |
| SRP219564 | CANX | 821 | RNAseq | 0.5974 | 0.0928 | |
| TCGA | CANX | 821 | RNAseq | -0.0408 | 0.2526 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CANX expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CANX:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CANX | 821 | 2 | 12 | 16 | |
| GSE20123 | CANX | 821 | 2 | 12 | 16 | |
| GSE43470 | CANX | 821 | 1 | 11 | 31 | |
| GSE46452 | CANX | 821 | 0 | 27 | 32 | |
| GSE47630 | CANX | 821 | 1 | 20 | 19 | |
| GSE54993 | CANX | 821 | 10 | 2 | 58 | |
| GSE54994 | CANX | 821 | 2 | 17 | 34 | |
| GSE60625 | CANX | 821 | 1 | 0 | 10 | |
| GSE74703 | CANX | 821 | 1 | 7 | 28 | |
| GSE74704 | CANX | 821 | 1 | 6 | 13 | |
| TCGA | CANX | 821 | 11 | 34 | 51 |
Total number of gains: 32; Total number of losses: 148; Total Number of normals: 308.
Somatic mutations of CANX:
Generating mutation plots.
Highly correlated genes for CANX:
Showing top 20/379 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CANX | NOMO1 | 0.748578 | 3 | 0 | 3 |
| CANX | CMSS1 | 0.730671 | 3 | 0 | 3 |
| CANX | KIF26B | 0.670647 | 4 | 0 | 4 |
| CANX | BBS5 | 0.647772 | 3 | 0 | 3 |
| CANX | KBTBD7 | 0.641351 | 3 | 0 | 3 |
| CANX | PLEKHG4B | 0.639435 | 5 | 0 | 5 |
| CANX | CDCA5 | 0.638242 | 3 | 0 | 3 |
| CANX | MRPL47 | 0.633004 | 3 | 0 | 3 |
| CANX | PPIA | 0.632339 | 3 | 0 | 3 |
| CANX | COL10A1 | 0.632129 | 6 | 0 | 5 |
| CANX | APOC1 | 0.628821 | 5 | 0 | 3 |
| CANX | CTHRC1 | 0.626456 | 6 | 0 | 4 |
| CANX | FTL | 0.62333 | 5 | 0 | 5 |
| CANX | TANGO2 | 0.622517 | 3 | 0 | 3 |
| CANX | DYRK2 | 0.6196 | 5 | 0 | 3 |
| CANX | MFAP2 | 0.616942 | 7 | 0 | 5 |
| CANX | TMEM123 | 0.612514 | 3 | 0 | 3 |
| CANX | C1orf43 | 0.612221 | 4 | 0 | 3 |
| CANX | TUBB | 0.611131 | 8 | 0 | 6 |
| CANX | HOXC13 | 0.606581 | 4 | 0 | 3 |
For details and further investigation, click here
