| Full name: coiled-coil domain containing 121 | Alias Symbol: FLJ43364|FLJ13646 | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 79635 | HGNC ID: HGNC:25833 | Ensembl Gene: ENSG00000176714 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC121:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC121 | 79635 | 220321_s_at | -0.2708 | 0.4665 | |
| GSE20347 | CCDC121 | 79635 | 220321_s_at | -0.0622 | 0.4148 | |
| GSE23400 | CCDC121 | 79635 | 220321_s_at | -0.0357 | 0.0489 | |
| GSE26886 | CCDC121 | 79635 | 220321_s_at | 0.0479 | 0.6642 | |
| GSE29001 | CCDC121 | 79635 | 220321_s_at | -0.1319 | 0.4285 | |
| GSE38129 | CCDC121 | 79635 | 220321_s_at | -0.1574 | 0.0727 | |
| GSE45670 | CCDC121 | 79635 | 220321_s_at | -0.2897 | 0.0903 | |
| GSE53622 | CCDC121 | 79635 | 12216 | 0.1713 | 0.2070 | |
| GSE53624 | CCDC121 | 79635 | 12216 | -0.1280 | 0.2031 | |
| GSE63941 | CCDC121 | 79635 | 220321_s_at | 0.4113 | 0.3384 | |
| GSE77861 | CCDC121 | 79635 | 220321_s_at | -0.0077 | 0.9318 | |
| GSE97050 | CCDC121 | 79635 | A_24_P319684 | -0.3852 | 0.3612 | |
| SRP007169 | CCDC121 | 79635 | RNAseq | 0.0634 | 0.9188 | |
| SRP064894 | CCDC121 | 79635 | RNAseq | -0.3098 | 0.2232 | |
| SRP133303 | CCDC121 | 79635 | RNAseq | -0.2528 | 0.2951 | |
| SRP159526 | CCDC121 | 79635 | RNAseq | 0.1613 | 0.6786 | |
| SRP193095 | CCDC121 | 79635 | RNAseq | -0.1357 | 0.4158 | |
| SRP219564 | CCDC121 | 79635 | RNAseq | -0.4031 | 0.3169 | |
| TCGA | CCDC121 | 79635 | RNAseq | -0.3234 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCDC121 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC121:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC121 | 79635 | 11 | 2 | 17 | |
| GSE20123 | CCDC121 | 79635 | 11 | 2 | 17 | |
| GSE43470 | CCDC121 | 79635 | 3 | 1 | 39 | |
| GSE46452 | CCDC121 | 79635 | 2 | 4 | 53 | |
| GSE47630 | CCDC121 | 79635 | 8 | 0 | 32 | |
| GSE54993 | CCDC121 | 79635 | 0 | 6 | 64 | |
| GSE54994 | CCDC121 | 79635 | 10 | 0 | 43 | |
| GSE60625 | CCDC121 | 79635 | 0 | 3 | 8 | |
| GSE74703 | CCDC121 | 79635 | 3 | 0 | 33 | |
| GSE74704 | CCDC121 | 79635 | 9 | 1 | 10 | |
| TCGA | CCDC121 | 79635 | 36 | 2 | 58 |
Total number of gains: 93; Total number of losses: 21; Total Number of normals: 374.
Somatic mutations of CCDC121:
Generating mutation plots.
Highly correlated genes for CCDC121:
Showing top 20/259 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC121 | PRKCA | 0.754034 | 3 | 0 | 3 |
| CCDC121 | RNF14 | 0.720115 | 4 | 0 | 3 |
| CCDC121 | CSDE1 | 0.714843 | 3 | 0 | 3 |
| CCDC121 | COG8 | 0.701336 | 3 | 0 | 3 |
| CCDC121 | PRKAG2 | 0.700364 | 3 | 0 | 3 |
| CCDC121 | TBCK | 0.694485 | 4 | 0 | 3 |
| CCDC121 | ANKRA2 | 0.691708 | 4 | 0 | 4 |
| CCDC121 | TSTD2 | 0.690596 | 3 | 0 | 3 |
| CCDC121 | PCBD2 | 0.690162 | 3 | 0 | 3 |
| CCDC121 | SUPT7L | 0.688161 | 3 | 0 | 3 |
| CCDC121 | STARD13 | 0.68551 | 3 | 0 | 3 |
| CCDC121 | ARIH2 | 0.683296 | 3 | 0 | 3 |
| CCDC121 | TTC21B | 0.679162 | 3 | 0 | 3 |
| CCDC121 | RNASE4 | 0.677413 | 5 | 0 | 4 |
| CCDC121 | LRRC20 | 0.671623 | 3 | 0 | 3 |
| CCDC121 | CASC4 | 0.670135 | 4 | 0 | 3 |
| CCDC121 | ANG | 0.669676 | 4 | 0 | 3 |
| CCDC121 | SOCS2 | 0.669306 | 3 | 0 | 3 |
| CCDC121 | GLCE | 0.669294 | 3 | 0 | 3 |
| CCDC121 | UGP2 | 0.666022 | 6 | 0 | 6 |
For details and further investigation, click here
