| Full name: component of oligomeric golgi complex 8 | Alias Symbol: FLJ22315|DOR1 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 84342 | HGNC ID: HGNC:18623 | Ensembl Gene: ENSG00000213380 | OMIM ID: 606979 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COG8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COG8 | 84342 | 227770_at | -0.0079 | 0.9875 | |
| GSE26886 | COG8 | 84342 | 227770_at | -0.1350 | 0.4544 | |
| GSE45670 | COG8 | 84342 | 227770_at | -0.1299 | 0.3082 | |
| GSE53622 | COG8 | 84342 | 12283 | 0.1516 | 0.0023 | |
| GSE53624 | COG8 | 84342 | 12283 | 0.4483 | 0.0000 | |
| GSE63941 | COG8 | 84342 | 227770_at | 0.1444 | 0.6715 | |
| GSE77861 | COG8 | 84342 | 227770_at | 0.1002 | 0.4387 | |
| GSE97050 | COG8 | 84342 | A_32_P92399 | 0.1663 | 0.4572 | |
| SRP007169 | COG8 | 84342 | RNAseq | -0.0089 | 0.9825 | |
| SRP008496 | COG8 | 84342 | RNAseq | 0.0930 | 0.7497 | |
| SRP064894 | COG8 | 84342 | RNAseq | -0.0137 | 0.9361 | |
| SRP133303 | COG8 | 84342 | RNAseq | -0.0129 | 0.9315 | |
| SRP159526 | COG8 | 84342 | RNAseq | 0.2534 | 0.1508 | |
| SRP193095 | COG8 | 84342 | RNAseq | 0.1354 | 0.1710 | |
| SRP219564 | COG8 | 84342 | RNAseq | 0.0487 | 0.8709 | |
| TCGA | COG8 | 84342 | RNAseq | -0.0859 | 0.1080 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COG8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COG8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COG8 | 84342 | 8 | 1 | 21 | |
| GSE20123 | COG8 | 84342 | 8 | 1 | 21 | |
| GSE43470 | COG8 | 84342 | 2 | 7 | 34 | |
| GSE46452 | COG8 | 84342 | 38 | 1 | 20 | |
| GSE47630 | COG8 | 84342 | 11 | 8 | 21 | |
| GSE54993 | COG8 | 84342 | 2 | 4 | 64 | |
| GSE54994 | COG8 | 84342 | 8 | 10 | 35 | |
| GSE60625 | COG8 | 84342 | 4 | 0 | 7 | |
| GSE74703 | COG8 | 84342 | 2 | 4 | 30 | |
| GSE74704 | COG8 | 84342 | 4 | 0 | 16 | |
| TCGA | COG8 | 84342 | 29 | 12 | 55 |
Total number of gains: 116; Total number of losses: 48; Total Number of normals: 324.
Somatic mutations of COG8:
Generating mutation plots.
Highly correlated genes for COG8:
Showing top 20/41 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COG8 | C16orf58 | 0.785338 | 3 | 0 | 3 |
| COG8 | CCDC121 | 0.701336 | 3 | 0 | 3 |
| COG8 | PAN2 | 0.70131 | 3 | 0 | 3 |
| COG8 | ZFC3H1 | 0.693694 | 3 | 0 | 3 |
| COG8 | WDR20 | 0.692116 | 3 | 0 | 3 |
| COG8 | CIAO1 | 0.690272 | 3 | 0 | 3 |
| COG8 | ERG | 0.685746 | 3 | 0 | 3 |
| COG8 | DEF8 | 0.675554 | 3 | 0 | 3 |
| COG8 | DDB1 | 0.669481 | 3 | 0 | 3 |
| COG8 | EFTUD2 | 0.665402 | 3 | 0 | 3 |
| COG8 | JAG1 | 0.658702 | 3 | 0 | 3 |
| COG8 | SLC7A6OS | 0.657209 | 4 | 0 | 3 |
| COG8 | TERF2 | 0.654879 | 4 | 0 | 3 |
| COG8 | BANF1 | 0.648259 | 3 | 0 | 3 |
| COG8 | DNMT1 | 0.64626 | 3 | 0 | 3 |
| COG8 | SERTAD4 | 0.645468 | 3 | 0 | 3 |
| COG8 | PLOD3 | 0.623844 | 3 | 0 | 3 |
| COG8 | MGAT3 | 0.621999 | 3 | 0 | 3 |
| COG8 | ARIH1 | 0.619655 | 4 | 0 | 3 |
| COG8 | MAVS | 0.608194 | 3 | 0 | 3 |
For details and further investigation, click here
