| Full name: coiled-coil domain containing 134 | Alias Symbol: FLJ22349 | ||
| Type: protein-coding gene | Cytoband: 22q13.2 | ||
| Entrez ID: 79879 | HGNC ID: HGNC:26185 | Ensembl Gene: ENSG00000100147 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC134:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC134 | 79879 | 235434_at | 0.5854 | 0.1308 | |
| GSE20347 | CCDC134 | 79879 | 220077_at | 0.0585 | 0.4557 | |
| GSE23400 | CCDC134 | 79879 | 220077_at | -0.1763 | 0.0001 | |
| GSE26886 | CCDC134 | 79879 | 235434_at | 0.3871 | 0.1496 | |
| GSE29001 | CCDC134 | 79879 | 220077_at | -0.0416 | 0.7565 | |
| GSE38129 | CCDC134 | 79879 | 220077_at | 0.0481 | 0.4771 | |
| GSE45670 | CCDC134 | 79879 | 235434_at | 0.9289 | 0.0000 | |
| GSE53622 | CCDC134 | 79879 | 38298 | 0.7126 | 0.0000 | |
| GSE53624 | CCDC134 | 79879 | 38298 | 0.7388 | 0.0000 | |
| GSE63941 | CCDC134 | 79879 | 235434_at | 0.7583 | 0.1632 | |
| GSE77861 | CCDC134 | 79879 | 220077_at | -0.1941 | 0.2037 | |
| GSE97050 | CCDC134 | 79879 | A_24_P194420 | 0.3613 | 0.2624 | |
| SRP007169 | CCDC134 | 79879 | RNAseq | 0.1189 | 0.8040 | |
| SRP008496 | CCDC134 | 79879 | RNAseq | 0.2164 | 0.5283 | |
| SRP064894 | CCDC134 | 79879 | RNAseq | 1.1790 | 0.0000 | |
| SRP133303 | CCDC134 | 79879 | RNAseq | 0.5665 | 0.0099 | |
| SRP159526 | CCDC134 | 79879 | RNAseq | 0.5122 | 0.0236 | |
| SRP193095 | CCDC134 | 79879 | RNAseq | 0.2242 | 0.0972 | |
| SRP219564 | CCDC134 | 79879 | RNAseq | 0.8573 | 0.1341 | |
| TCGA | CCDC134 | 79879 | RNAseq | 0.0430 | 0.6526 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CCDC134 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC134:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC134 | 79879 | 6 | 5 | 19 | |
| GSE20123 | CCDC134 | 79879 | 6 | 4 | 20 | |
| GSE43470 | CCDC134 | 79879 | 5 | 6 | 32 | |
| GSE46452 | CCDC134 | 79879 | 31 | 2 | 26 | |
| GSE47630 | CCDC134 | 79879 | 9 | 4 | 27 | |
| GSE54993 | CCDC134 | 79879 | 3 | 6 | 61 | |
| GSE54994 | CCDC134 | 79879 | 11 | 8 | 34 | |
| GSE60625 | CCDC134 | 79879 | 5 | 0 | 6 | |
| GSE74703 | CCDC134 | 79879 | 5 | 4 | 27 | |
| GSE74704 | CCDC134 | 79879 | 3 | 2 | 15 | |
| TCGA | CCDC134 | 79879 | 27 | 14 | 55 |
Total number of gains: 111; Total number of losses: 55; Total Number of normals: 322.
Somatic mutations of CCDC134:
Generating mutation plots.
Highly correlated genes for CCDC134:
Showing top 20/344 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC134 | PAX5 | 0.684467 | 4 | 0 | 4 |
| CCDC134 | SLC19A1 | 0.680131 | 3 | 0 | 3 |
| CCDC134 | SNAP47 | 0.678767 | 3 | 0 | 3 |
| CCDC134 | POLR1A | 0.657132 | 3 | 0 | 3 |
| CCDC134 | FOXRED2 | 0.655598 | 6 | 0 | 5 |
| CCDC134 | STEAP1B | 0.654594 | 3 | 0 | 3 |
| CCDC134 | ZSCAN2 | 0.654324 | 7 | 0 | 7 |
| CCDC134 | CCDC137 | 0.654245 | 3 | 0 | 3 |
| CCDC134 | SLC26A6 | 0.651331 | 3 | 0 | 3 |
| CCDC134 | PRKDC | 0.649234 | 5 | 0 | 5 |
| CCDC134 | PTDSS1 | 0.649074 | 4 | 0 | 4 |
| CCDC134 | IBSP | 0.647973 | 3 | 0 | 3 |
| CCDC134 | DNAJB11 | 0.647816 | 5 | 0 | 4 |
| CCDC134 | FMNL3 | 0.647774 | 6 | 0 | 5 |
| CCDC134 | CCDC117 | 0.644998 | 4 | 0 | 3 |
| CCDC134 | LHX2 | 0.644009 | 5 | 0 | 4 |
| CCDC134 | TNFRSF18 | 0.641554 | 5 | 0 | 5 |
| CCDC134 | C16orf74 | 0.637321 | 5 | 0 | 4 |
| CCDC134 | PYCR2 | 0.634384 | 3 | 0 | 3 |
| CCDC134 | IL32 | 0.633803 | 4 | 0 | 3 |
For details and further investigation, click here
