| Full name: coiled-coil domain containing 137 | Alias Symbol: MGC16597 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 339230 | HGNC ID: HGNC:33451 | Ensembl Gene: ENSG00000185298 | OMIM ID: 614271 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CCDC137:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC137 | 339230 | 225933_at | 0.5687 | 0.2129 | |
| GSE26886 | CCDC137 | 339230 | 225933_at | 0.2710 | 0.2160 | |
| GSE45670 | CCDC137 | 339230 | 225933_at | 0.5697 | 0.0004 | |
| GSE53622 | CCDC137 | 339230 | 13032 | 0.4258 | 0.0000 | |
| GSE53624 | CCDC137 | 339230 | 13032 | 0.3221 | 0.0000 | |
| GSE63941 | CCDC137 | 339230 | 225933_at | 0.2172 | 0.5821 | |
| GSE77861 | CCDC137 | 339230 | 225933_at | 0.0362 | 0.8564 | |
| GSE97050 | CCDC137 | 339230 | A_24_P230176 | 0.3463 | 0.2420 | |
| SRP007169 | CCDC137 | 339230 | RNAseq | 0.2300 | 0.6644 | |
| SRP008496 | CCDC137 | 339230 | RNAseq | 0.4744 | 0.1882 | |
| SRP064894 | CCDC137 | 339230 | RNAseq | 0.8298 | 0.0001 | |
| SRP133303 | CCDC137 | 339230 | RNAseq | 0.4066 | 0.0119 | |
| SRP159526 | CCDC137 | 339230 | RNAseq | 0.0535 | 0.8497 | |
| SRP193095 | CCDC137 | 339230 | RNAseq | 0.0551 | 0.6399 | |
| SRP219564 | CCDC137 | 339230 | RNAseq | 0.0479 | 0.9030 | |
| TCGA | CCDC137 | 339230 | RNAseq | 0.2468 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCDC137 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC137:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC137 | 339230 | 4 | 4 | 22 | |
| GSE20123 | CCDC137 | 339230 | 4 | 4 | 22 | |
| GSE43470 | CCDC137 | 339230 | 3 | 5 | 35 | |
| GSE46452 | CCDC137 | 339230 | 34 | 0 | 25 | |
| GSE47630 | CCDC137 | 339230 | 9 | 2 | 29 | |
| GSE54993 | CCDC137 | 339230 | 2 | 5 | 63 | |
| GSE54994 | CCDC137 | 339230 | 10 | 6 | 37 | |
| GSE60625 | CCDC137 | 339230 | 6 | 0 | 5 | |
| GSE74703 | CCDC137 | 339230 | 3 | 3 | 30 | |
| GSE74704 | CCDC137 | 339230 | 4 | 3 | 13 | |
| TCGA | CCDC137 | 339230 | 25 | 12 | 59 |
Total number of gains: 104; Total number of losses: 44; Total Number of normals: 340.
Somatic mutations of CCDC137:
Generating mutation plots.
Highly correlated genes for CCDC137:
Showing top 20/499 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC137 | CEBPA | 0.731785 | 3 | 0 | 3 |
| CCDC137 | LSM4 | 0.71779 | 3 | 0 | 3 |
| CCDC137 | TSEN54 | 0.692662 | 4 | 0 | 3 |
| CCDC137 | STK11 | 0.692631 | 3 | 0 | 3 |
| CCDC137 | DSCC1 | 0.690255 | 3 | 0 | 3 |
| CCDC137 | MRPL12 | 0.688738 | 5 | 0 | 4 |
| CCDC137 | HGS | 0.685864 | 5 | 0 | 5 |
| CCDC137 | FASN | 0.685436 | 4 | 0 | 4 |
| CCDC137 | FNBP1L | 0.683845 | 3 | 0 | 3 |
| CCDC137 | DPP3 | 0.680674 | 4 | 0 | 4 |
| CCDC137 | CDK2AP2 | 0.678044 | 3 | 0 | 3 |
| CCDC137 | APEX2 | 0.676563 | 4 | 0 | 4 |
| CCDC137 | GNB2 | 0.675808 | 4 | 0 | 4 |
| CCDC137 | BNC1 | 0.670154 | 3 | 0 | 3 |
| CCDC137 | NACC1 | 0.668654 | 3 | 0 | 3 |
| CCDC137 | RCC1 | 0.666468 | 5 | 0 | 4 |
| CCDC137 | CCDC134 | 0.654245 | 3 | 0 | 3 |
| CCDC137 | B4GALNT3 | 0.653672 | 3 | 0 | 3 |
| CCDC137 | MKI67 | 0.653284 | 5 | 0 | 4 |
| CCDC137 | DNAJC9 | 0.652916 | 3 | 0 | 3 |
For details and further investigation, click here
