| Full name: solute carrier family 26 member 6 | Alias Symbol: DKFZp586E1422 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 65010 | HGNC ID: HGNC:14472 | Ensembl Gene: ENSG00000225697 | OMIM ID: 610068 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC26A6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC26A6 | 65010 | 232551_at | 0.1495 | 0.8294 | |
| GSE26886 | SLC26A6 | 65010 | 232551_at | -0.5916 | 0.0032 | |
| GSE45670 | SLC26A6 | 65010 | 232551_at | 0.1582 | 0.2910 | |
| GSE53622 | SLC26A6 | 65010 | 121509 | 1.2007 | 0.0000 | |
| GSE53624 | SLC26A6 | 65010 | 121509 | 1.2526 | 0.0000 | |
| GSE63941 | SLC26A6 | 65010 | 232551_at | 0.7200 | 0.1628 | |
| GSE77861 | SLC26A6 | 65010 | 232551_at | 0.1108 | 0.5135 | |
| GSE97050 | SLC26A6 | 65010 | A_23_P109895 | 0.7548 | 0.1048 | |
| SRP007169 | SLC26A6 | 65010 | RNAseq | 2.2389 | 0.0001 | |
| SRP008496 | SLC26A6 | 65010 | RNAseq | 1.7185 | 0.0000 | |
| SRP064894 | SLC26A6 | 65010 | RNAseq | 1.9741 | 0.0000 | |
| SRP133303 | SLC26A6 | 65010 | RNAseq | 0.9840 | 0.0000 | |
| SRP159526 | SLC26A6 | 65010 | RNAseq | 1.3900 | 0.0002 | |
| SRP193095 | SLC26A6 | 65010 | RNAseq | 1.0655 | 0.0000 | |
| SRP219564 | SLC26A6 | 65010 | RNAseq | 0.8965 | 0.0421 | |
| TCGA | SLC26A6 | 65010 | RNAseq | -0.1227 | 0.0970 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by SLC26A6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC26A6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC26A6 | 65010 | 0 | 18 | 12 | |
| GSE20123 | SLC26A6 | 65010 | 0 | 19 | 11 | |
| GSE43470 | SLC26A6 | 65010 | 0 | 19 | 24 | |
| GSE46452 | SLC26A6 | 65010 | 3 | 16 | 40 | |
| GSE47630 | SLC26A6 | 65010 | 1 | 24 | 15 | |
| GSE54993 | SLC26A6 | 65010 | 6 | 2 | 62 | |
| GSE54994 | SLC26A6 | 65010 | 0 | 36 | 17 | |
| GSE60625 | SLC26A6 | 65010 | 5 | 0 | 6 | |
| GSE74703 | SLC26A6 | 65010 | 0 | 15 | 21 | |
| GSE74704 | SLC26A6 | 65010 | 0 | 12 | 8 | |
| TCGA | SLC26A6 | 65010 | 0 | 78 | 18 |
Total number of gains: 15; Total number of losses: 239; Total Number of normals: 234.
Somatic mutations of SLC26A6:
Generating mutation plots.
Highly correlated genes for SLC26A6:
Showing top 20/269 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC26A6 | SLC19A1 | 0.794778 | 3 | 0 | 3 |
| SLC26A6 | FAM89A | 0.777943 | 3 | 0 | 3 |
| SLC26A6 | MOGS | 0.777819 | 3 | 0 | 3 |
| SLC26A6 | EML4 | 0.750132 | 3 | 0 | 3 |
| SLC26A6 | CEP55 | 0.747209 | 3 | 0 | 3 |
| SLC26A6 | KIF20A | 0.739898 | 3 | 0 | 3 |
| SLC26A6 | AATF | 0.737579 | 3 | 0 | 3 |
| SLC26A6 | STIL | 0.73362 | 3 | 0 | 3 |
| SLC26A6 | PLK1 | 0.726568 | 3 | 0 | 3 |
| SLC26A6 | NME1 | 0.720721 | 3 | 0 | 3 |
| SLC26A6 | THOC6 | 0.720425 | 3 | 0 | 3 |
| SLC26A6 | PRR14L | 0.709259 | 4 | 0 | 3 |
| SLC26A6 | CLSPN | 0.709179 | 3 | 0 | 3 |
| SLC26A6 | ANLN | 0.705753 | 3 | 0 | 3 |
| SLC26A6 | PYCR2 | 0.702743 | 3 | 0 | 3 |
| SLC26A6 | CDCA3 | 0.699401 | 3 | 0 | 3 |
| SLC26A6 | LMNB2 | 0.69838 | 3 | 0 | 3 |
| SLC26A6 | MASTL | 0.697111 | 3 | 0 | 3 |
| SLC26A6 | DNAJB11 | 0.695098 | 4 | 0 | 3 |
| SLC26A6 | NDC80 | 0.694203 | 3 | 0 | 3 |
For details and further investigation, click here
