ARMC8

 

Full name: armadillo repeat containing 8 Alias Symbol: HSPC056|DKFZP434A043|GID5|VID28
Type: protein-coding gene Cytoband: 3q22.3
Entrez ID: 25852 HGNC ID: HGNC:24999 Ensembl Gene: ENSG00000114098 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ARMC8:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ARMC8 25852 203486_s_at 0.4116 0.2593
GSE20347 ARMC8 25852 203486_s_at 0.2663 0.1141
GSE23400 ARMC8 25852 203486_s_at 0.2787 0.0004
GSE26886 ARMC8 25852 203486_s_at -1.1763 0.0000
GSE29001 ARMC8 25852 203487_s_at 0.3876 0.3230
GSE38129 ARMC8 25852 203486_s_at 0.1248 0.3502
GSE45670 ARMC8 25852 203486_s_at -0.0465 0.7693
GSE53622 ARMC8 25852 42299 -0.0143 0.9001
GSE53624 ARMC8 25852 42299 0.1206 0.1015
GSE63941 ARMC8 25852 203486_s_at 0.3697 0.2948
GSE77861 ARMC8 25852 203486_s_at 0.3460 0.2958
GSE97050 ARMC8 25852 A_23_P18384 0.0593 0.7607
SRP007169 ARMC8 25852 RNAseq 0.6442 0.0689
SRP008496 ARMC8 25852 RNAseq 0.8161 0.0001
SRP064894 ARMC8 25852 RNAseq 0.1081 0.4809
SRP133303 ARMC8 25852 RNAseq 0.3565 0.0174
SRP159526 ARMC8 25852 RNAseq 0.3358 0.2148
SRP193095 ARMC8 25852 RNAseq 0.2245 0.0262
SRP219564 ARMC8 25852 RNAseq -0.0484 0.8664
TCGA ARMC8 25852 RNAseq 0.0189 0.7091

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by ARMC8 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ARMC8:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ARMC8 25852 17 0 13
GSE20123 ARMC8 25852 17 0 13
GSE43470 ARMC8 25852 22 0 21
GSE46452 ARMC8 25852 15 4 40
GSE47630 ARMC8 25852 18 3 19
GSE54993 ARMC8 25852 2 8 60
GSE54994 ARMC8 25852 32 1 20
GSE60625 ARMC8 25852 0 6 5
GSE74703 ARMC8 25852 19 0 17
GSE74704 ARMC8 25852 11 0 9
TCGA ARMC8 25852 62 4 30

Total number of gains: 215; Total number of losses: 26; Total Number of normals: 247.  


 

Somatic mutations of ARMC8:

 

Generating mutation plots.

 

Highly correlated genes for ARMC8:

 

Showing top 20/215 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ARMC8FASTKD10.802248303
ARMC8PARP140.800046303
ARMC8SETX0.797083303
ARMC8CCDC180.771053303
ARMC8HS6ST10.753501303
ARMC8WDR770.73343303
ARMC8SHISA50.732976303
ARMC8ZNF518B0.711101303
ARMC8RBM450.71021404
ARMC8TMEM1380.708134303
ARMC8UTP230.70519303
ARMC8EBPL0.702512303
ARMC8VANGL20.700637303
ARMC8TMEM1170.700611303
ARMC8PAN20.699248303
ARMC8TOMM40L0.693119303
ARMC8CRNKL10.692157403
ARMC8CD530.686309303
ARMC8FUCA20.683769303
ARMC8DTX3L0.679205303

For details and further investigation, click here