| Full name: fucosyltransferase 4 | Alias Symbol: FUC-TIV | ||
| Type: protein-coding gene | Cytoband: 11q21 | ||
| Entrez ID: 2526 | HGNC ID: HGNC:4015 | Ensembl Gene: ENSG00000196371 | OMIM ID: 104230 |
| Drug and gene relationship at DGIdb | |||
Expression of FUT4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FUT4 | 2526 | 209892_at | -0.5633 | 0.2169 | |
| GSE20347 | FUT4 | 2526 | 209893_s_at | 0.2249 | 0.0631 | |
| GSE23400 | FUT4 | 2526 | 209893_s_at | 0.0783 | 0.0366 | |
| GSE26886 | FUT4 | 2526 | 209893_s_at | 0.4972 | 0.0004 | |
| GSE29001 | FUT4 | 2526 | 209892_at | 0.0878 | 0.6758 | |
| GSE38129 | FUT4 | 2526 | 209893_s_at | 0.1387 | 0.1781 | |
| GSE45670 | FUT4 | 2526 | 209892_at | -0.4784 | 0.0240 | |
| GSE53622 | FUT4 | 2526 | 81727 | -0.1848 | 0.1267 | |
| GSE53624 | FUT4 | 2526 | 81727 | -0.2089 | 0.1493 | |
| GSE63941 | FUT4 | 2526 | 209893_s_at | -1.5394 | 0.0090 | |
| GSE77861 | FUT4 | 2526 | 209893_s_at | -0.0491 | 0.6659 | |
| GSE97050 | FUT4 | 2526 | A_33_P3286536 | 0.1576 | 0.6154 | |
| SRP007169 | FUT4 | 2526 | RNAseq | 0.7516 | 0.1508 | |
| SRP008496 | FUT4 | 2526 | RNAseq | 0.8462 | 0.0517 | |
| SRP064894 | FUT4 | 2526 | RNAseq | 0.1782 | 0.4873 | |
| SRP133303 | FUT4 | 2526 | RNAseq | -0.0255 | 0.8765 | |
| SRP159526 | FUT4 | 2526 | RNAseq | 0.1267 | 0.7016 | |
| SRP193095 | FUT4 | 2526 | RNAseq | -0.7173 | 0.0893 | |
| SRP219564 | FUT4 | 2526 | RNAseq | -0.1772 | 0.6934 | |
| TCGA | FUT4 | 2526 | RNAseq | -0.6540 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FUT4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FUT4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FUT4 | 2526 | 3 | 9 | 18 | |
| GSE20123 | FUT4 | 2526 | 3 | 9 | 18 | |
| GSE43470 | FUT4 | 2526 | 2 | 5 | 36 | |
| GSE46452 | FUT4 | 2526 | 5 | 24 | 30 | |
| GSE47630 | FUT4 | 2526 | 2 | 19 | 19 | |
| GSE54993 | FUT4 | 2526 | 8 | 2 | 60 | |
| GSE54994 | FUT4 | 2526 | 6 | 18 | 29 | |
| GSE60625 | FUT4 | 2526 | 0 | 3 | 8 | |
| GSE74703 | FUT4 | 2526 | 1 | 4 | 31 | |
| GSE74704 | FUT4 | 2526 | 3 | 5 | 12 | |
| TCGA | FUT4 | 2526 | 11 | 43 | 42 |
Total number of gains: 44; Total number of losses: 141; Total Number of normals: 303.
Somatic mutations of FUT4:
Generating mutation plots.
Highly correlated genes for FUT4:
Showing top 20/171 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FUT4 | MAP1A | 0.697746 | 3 | 0 | 3 |
| FUT4 | ZNF469 | 0.687111 | 3 | 0 | 3 |
| FUT4 | MICAL1 | 0.677169 | 3 | 0 | 3 |
| FUT4 | PXDN | 0.653418 | 3 | 0 | 3 |
| FUT4 | VGLL3 | 0.639875 | 4 | 0 | 4 |
| FUT4 | GRIK2 | 0.63638 | 3 | 0 | 3 |
| FUT4 | UHRF1BP1L | 0.623331 | 5 | 0 | 4 |
| FUT4 | NBPF20 | 0.618114 | 3 | 0 | 3 |
| FUT4 | PAMR1 | 0.612614 | 4 | 0 | 3 |
| FUT4 | FDXACB1 | 0.610073 | 3 | 0 | 3 |
| FUT4 | DMRTA1 | 0.605943 | 3 | 0 | 3 |
| FUT4 | PEAK1 | 0.604888 | 5 | 0 | 3 |
| FUT4 | HOXB5 | 0.604215 | 3 | 0 | 3 |
| FUT4 | GFRA1 | 0.602995 | 4 | 0 | 3 |
| FUT4 | CLEC11A | 0.602309 | 5 | 0 | 3 |
| FUT4 | MSRB3 | 0.602129 | 4 | 0 | 3 |
| FUT4 | ADAMTS3 | 0.601144 | 4 | 0 | 3 |
| FUT4 | PRICKLE2 | 0.598988 | 4 | 0 | 3 |
| FUT4 | AMPH | 0.597657 | 4 | 0 | 4 |
| FUT4 | ARHGAP20 | 0.589507 | 4 | 0 | 3 |
For details and further investigation, click here
