| Full name: pyrimidinergic receptor P2Y6 | Alias Symbol: P2Y6 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 5031 | HGNC ID: HGNC:8543 | Ensembl Gene: ENSG00000171631 | OMIM ID: 602451 |
| Drug and gene relationship at DGIdb | |||
Expression of P2RY6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | P2RY6 | 5031 | 208373_s_at | 0.5034 | 0.0725 | |
| GSE20347 | P2RY6 | 5031 | 208373_s_at | 0.3181 | 0.0022 | |
| GSE23400 | P2RY6 | 5031 | 208373_s_at | 0.0705 | 0.0987 | |
| GSE26886 | P2RY6 | 5031 | 208373_s_at | 0.3539 | 0.4075 | |
| GSE29001 | P2RY6 | 5031 | 208373_s_at | 0.1471 | 0.3243 | |
| GSE38129 | P2RY6 | 5031 | 208373_s_at | 0.2848 | 0.0264 | |
| GSE45670 | P2RY6 | 5031 | 208373_s_at | 0.8698 | 0.0027 | |
| GSE53622 | P2RY6 | 5031 | 77008 | 1.3439 | 0.0000 | |
| GSE53624 | P2RY6 | 5031 | 77008 | 1.2433 | 0.0000 | |
| GSE63941 | P2RY6 | 5031 | 208373_s_at | 0.4869 | 0.2312 | |
| GSE77861 | P2RY6 | 5031 | 208373_s_at | 0.2061 | 0.1223 | |
| GSE97050 | P2RY6 | 5031 | A_23_P64611 | 0.7648 | 0.3083 | |
| SRP007169 | P2RY6 | 5031 | RNAseq | 2.1256 | 0.0277 | |
| SRP064894 | P2RY6 | 5031 | RNAseq | 2.4087 | 0.0000 | |
| SRP133303 | P2RY6 | 5031 | RNAseq | 0.9084 | 0.0080 | |
| SRP159526 | P2RY6 | 5031 | RNAseq | 1.9022 | 0.0020 | |
| SRP219564 | P2RY6 | 5031 | RNAseq | 1.8078 | 0.0007 | |
| TCGA | P2RY6 | 5031 | RNAseq | 0.9395 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by P2RY6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of P2RY6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | P2RY6 | 5031 | 8 | 7 | 15 | |
| GSE20123 | P2RY6 | 5031 | 8 | 7 | 15 | |
| GSE43470 | P2RY6 | 5031 | 9 | 2 | 32 | |
| GSE46452 | P2RY6 | 5031 | 10 | 19 | 30 | |
| GSE47630 | P2RY6 | 5031 | 7 | 13 | 20 | |
| GSE54993 | P2RY6 | 5031 | 8 | 2 | 60 | |
| GSE54994 | P2RY6 | 5031 | 8 | 15 | 30 | |
| GSE60625 | P2RY6 | 5031 | 0 | 7 | 4 | |
| GSE74703 | P2RY6 | 5031 | 7 | 2 | 27 | |
| GSE74704 | P2RY6 | 5031 | 6 | 3 | 11 | |
| TCGA | P2RY6 | 5031 | 28 | 27 | 41 |
Total number of gains: 99; Total number of losses: 104; Total Number of normals: 285.
Somatic mutations of P2RY6:
Generating mutation plots.
Highly correlated genes for P2RY6:
Showing top 20/858 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| P2RY6 | PREB | 0.745577 | 3 | 0 | 3 |
| P2RY6 | CXCL9 | 0.716521 | 3 | 0 | 3 |
| P2RY6 | CD300C | 0.710728 | 4 | 0 | 4 |
| P2RY6 | FCGR3A | 0.708429 | 3 | 0 | 3 |
| P2RY6 | FMNL3 | 0.691346 | 4 | 0 | 4 |
| P2RY6 | FAM169A | 0.689846 | 3 | 0 | 3 |
| P2RY6 | LRRC25 | 0.68897 | 3 | 0 | 3 |
| P2RY6 | COA6 | 0.684472 | 3 | 0 | 3 |
| P2RY6 | TNFRSF18 | 0.684226 | 3 | 0 | 3 |
| P2RY6 | SUCNR1 | 0.680611 | 3 | 0 | 3 |
| P2RY6 | A4GALT | 0.679282 | 3 | 0 | 3 |
| P2RY6 | PARL | 0.679162 | 3 | 0 | 3 |
| P2RY6 | MRPS12 | 0.673494 | 4 | 0 | 3 |
| P2RY6 | PSMD3 | 0.668171 | 4 | 0 | 4 |
| P2RY6 | LRRC8C | 0.666637 | 3 | 0 | 3 |
| P2RY6 | ORAI1 | 0.664022 | 4 | 0 | 3 |
| P2RY6 | ADAM8 | 0.663988 | 4 | 0 | 3 |
| P2RY6 | TTYH3 | 0.661458 | 6 | 0 | 6 |
| P2RY6 | DDX39A | 0.654553 | 6 | 0 | 4 |
| P2RY6 | TMPO-AS1 | 0.654015 | 4 | 0 | 4 |
For details and further investigation, click here
