| Full name: cyclin dependent kinase 19 | Alias Symbol: KIAA1028|bA346C16.3 | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 23097 | HGNC ID: HGNC:19338 | Ensembl Gene: ENSG00000155111 | OMIM ID: 614720 |
| Drug and gene relationship at DGIdb | |||
Expression of CDK19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDK19 | 23097 | 212899_at | -0.7905 | 0.0331 | |
| GSE20347 | CDK19 | 23097 | 212899_at | -1.1667 | 0.0000 | |
| GSE23400 | CDK19 | 23097 | 212897_at | -0.1927 | 0.0000 | |
| GSE26886 | CDK19 | 23097 | 212899_at | -0.9866 | 0.0004 | |
| GSE29001 | CDK19 | 23097 | 212899_at | -0.7496 | 0.0030 | |
| GSE38129 | CDK19 | 23097 | 212899_at | -0.8398 | 0.0000 | |
| GSE45670 | CDK19 | 23097 | 212899_at | -0.4075 | 0.0291 | |
| GSE53622 | CDK19 | 23097 | 86528 | -0.8819 | 0.0000 | |
| GSE53624 | CDK19 | 23097 | 86528 | -0.8825 | 0.0000 | |
| GSE63941 | CDK19 | 23097 | 212899_at | -0.9480 | 0.1864 | |
| GSE77861 | CDK19 | 23097 | 212897_at | -0.1589 | 0.3065 | |
| GSE97050 | CDK19 | 23097 | A_33_P3328026 | -0.3890 | 0.2144 | |
| SRP007169 | CDK19 | 23097 | RNAseq | -0.8811 | 0.0031 | |
| SRP008496 | CDK19 | 23097 | RNAseq | -0.8693 | 0.0000 | |
| SRP064894 | CDK19 | 23097 | RNAseq | -0.6119 | 0.0051 | |
| SRP133303 | CDK19 | 23097 | RNAseq | -0.5676 | 0.0003 | |
| SRP159526 | CDK19 | 23097 | RNAseq | -0.7443 | 0.0164 | |
| SRP193095 | CDK19 | 23097 | RNAseq | -0.8858 | 0.0000 | |
| SRP219564 | CDK19 | 23097 | RNAseq | -0.9234 | 0.0165 | |
| TCGA | CDK19 | 23097 | RNAseq | -0.0782 | 0.1693 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CDK19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDK19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDK19 | 23097 | 2 | 3 | 25 | |
| GSE20123 | CDK19 | 23097 | 2 | 3 | 25 | |
| GSE43470 | CDK19 | 23097 | 3 | 1 | 39 | |
| GSE46452 | CDK19 | 23097 | 2 | 11 | 46 | |
| GSE47630 | CDK19 | 23097 | 9 | 4 | 27 | |
| GSE54993 | CDK19 | 23097 | 3 | 2 | 65 | |
| GSE54994 | CDK19 | 23097 | 8 | 8 | 37 | |
| GSE60625 | CDK19 | 23097 | 0 | 2 | 9 | |
| GSE74703 | CDK19 | 23097 | 2 | 1 | 33 | |
| GSE74704 | CDK19 | 23097 | 0 | 1 | 19 | |
| TCGA | CDK19 | 23097 | 6 | 23 | 67 |
Total number of gains: 37; Total number of losses: 59; Total Number of normals: 392.
Somatic mutations of CDK19:
Generating mutation plots.
Highly correlated genes for CDK19:
Showing top 20/1259 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDK19 | ZNF554 | 0.734138 | 3 | 0 | 3 |
| CDK19 | SPNS2 | 0.719306 | 3 | 0 | 3 |
| CDK19 | RRAGD | 0.717845 | 11 | 0 | 10 |
| CDK19 | ZNF431 | 0.713533 | 4 | 0 | 4 |
| CDK19 | UBL3 | 0.712517 | 10 | 0 | 10 |
| CDK19 | YPEL3 | 0.711904 | 6 | 0 | 5 |
| CDK19 | SAMD5 | 0.711393 | 6 | 0 | 6 |
| CDK19 | SCNN1B | 0.703937 | 9 | 0 | 8 |
| CDK19 | SMIM5 | 0.703265 | 5 | 0 | 5 |
| CDK19 | DLG2 | 0.702302 | 9 | 0 | 9 |
| CDK19 | SH3BGRL2 | 0.700402 | 7 | 0 | 6 |
| CDK19 | DBNL | 0.699916 | 3 | 0 | 3 |
| CDK19 | PLEKHG6 | 0.699175 | 9 | 0 | 8 |
| CDK19 | HACE1 | 0.699153 | 6 | 0 | 6 |
| CDK19 | SORT1 | 0.699 | 11 | 0 | 10 |
| CDK19 | PLEKHA7 | 0.695859 | 6 | 0 | 6 |
| CDK19 | KLHDC7A | 0.695678 | 3 | 0 | 3 |
| CDK19 | GYS2 | 0.693287 | 9 | 0 | 8 |
| CDK19 | HBP1 | 0.691835 | 9 | 0 | 9 |
| CDK19 | CGNL1 | 0.691719 | 7 | 0 | 6 |
For details and further investigation, click here
