| Full name: drebrin like | Alias Symbol: SH3P7|HIP-55|ABP1 | ||
| Type: protein-coding gene | Cytoband: 7p13 | ||
| Entrez ID: 28988 | HGNC ID: HGNC:2696 | Ensembl Gene: ENSG00000136279 | OMIM ID: 610106 |
| Drug and gene relationship at DGIdb | |||
Expression of DBNL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | DBNL | 28988 | 62666 | -0.9614 | 0.0000 | |
| GSE53624 | DBNL | 28988 | 62666 | -1.3116 | 0.0000 | |
| GSE97050 | DBNL | 28988 | A_33_P3211260 | -0.3770 | 0.1880 | |
| SRP007169 | DBNL | 28988 | RNAseq | -2.4621 | 0.0000 | |
| SRP008496 | DBNL | 28988 | RNAseq | -2.4036 | 0.0000 | |
| SRP064894 | DBNL | 28988 | RNAseq | -0.9620 | 0.0002 | |
| SRP133303 | DBNL | 28988 | RNAseq | -0.8302 | 0.0000 | |
| SRP159526 | DBNL | 28988 | RNAseq | -1.1790 | 0.0000 | |
| SRP193095 | DBNL | 28988 | RNAseq | -1.0398 | 0.0000 | |
| SRP219564 | DBNL | 28988 | RNAseq | -1.1388 | 0.0011 | |
| TCGA | DBNL | 28988 | RNAseq | 0.0154 | 0.7752 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by DBNL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DBNL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DBNL | 28988 | 14 | 0 | 16 | |
| GSE20123 | DBNL | 28988 | 13 | 0 | 17 | |
| GSE43470 | DBNL | 28988 | 4 | 0 | 39 | |
| GSE46452 | DBNL | 28988 | 11 | 1 | 47 | |
| GSE47630 | DBNL | 28988 | 8 | 1 | 31 | |
| GSE54993 | DBNL | 28988 | 0 | 8 | 62 | |
| GSE54994 | DBNL | 28988 | 17 | 3 | 33 | |
| GSE60625 | DBNL | 28988 | 0 | 0 | 11 | |
| GSE74703 | DBNL | 28988 | 4 | 0 | 32 | |
| GSE74704 | DBNL | 28988 | 7 | 0 | 13 | |
| TCGA | DBNL | 28988 | 51 | 7 | 38 |
Total number of gains: 129; Total number of losses: 20; Total Number of normals: 339.
Somatic mutations of DBNL:
Generating mutation plots.
Highly correlated genes for DBNL:
Showing top 20/230 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DBNL | CXCR2 | 0.806064 | 3 | 0 | 3 |
| DBNL | MGLL | 0.734271 | 3 | 0 | 3 |
| DBNL | SLC46A2 | 0.732033 | 3 | 0 | 3 |
| DBNL | SH3GLB2 | 0.728507 | 3 | 0 | 3 |
| DBNL | LMNA | 0.725823 | 3 | 0 | 3 |
| DBNL | KIF1C | 0.725813 | 3 | 0 | 3 |
| DBNL | TRIP10 | 0.720944 | 3 | 0 | 3 |
| DBNL | PPP1R7 | 0.718013 | 3 | 0 | 3 |
| DBNL | TRNP1 | 0.714198 | 3 | 0 | 3 |
| DBNL | KANK1 | 0.712808 | 3 | 0 | 3 |
| DBNL | RMND5B | 0.711338 | 3 | 0 | 3 |
| DBNL | BLVRA | 0.711137 | 3 | 0 | 3 |
| DBNL | PLCD1 | 0.71006 | 3 | 0 | 3 |
| DBNL | ACADVL | 0.706882 | 3 | 0 | 3 |
| DBNL | PMVK | 0.706859 | 3 | 0 | 3 |
| DBNL | CMAS | 0.703901 | 3 | 0 | 3 |
| DBNL | CAPN5 | 0.702539 | 3 | 0 | 3 |
| DBNL | CDK19 | 0.699916 | 3 | 0 | 3 |
| DBNL | SLC24A3 | 0.698209 | 3 | 0 | 3 |
| DBNL | MYZAP | 0.697752 | 3 | 0 | 3 |
For details and further investigation, click here
